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Furry Family Pre
Furry Family Pre

... 6) In dogs, assume that black fur is dominant and brown fur is recessive. A male black dog and a female brown dog have a puppy, which is brown. Which most likely describes the genes of the parent dogs? a. Both parents carry the recessive genes b. The male parent carries the recessive gene, while the ...
origins debate intro
origins debate intro

... can encode information, and its structure makes it easy to pass on this information to descendants. Unfortunately, DNA does not have catalytic ability and so cannot replicate on its own. It needs proteins. Next, let’s assume that proteins arose first. Proteins are very versatile and can carry out a ...
Does Activation of the TALl Gene Occur in a Majority
Does Activation of the TALl Gene Occur in a Majority

... locus.’-” Although this translocation is only observed in approximately 3% of T-ALL patients,” an additional 25% of patients harbor a tumor-specific rearrangement of TALI that is not detected cyt~genetically.’~”~ This rearrangement arises from a local DNA deletion (the tald recombination) that remov ...
SNP Array Activity Learning Objectives Introduction
SNP Array Activity Learning Objectives Introduction

... have entered widespread use in the wake of the Human Genome Project and improvements in sequencing technology. DNA Microarrays DNA microarrays (also called DNA arrays and gene chips) are manufactured by placing many singlestranded DNA molecules with a single known sequence in a single spot on a glas ...
1 - MPEG
1 - MPEG

... characteristics are called “variants” because they are expressed as differences between the organism under study and a reference genome. Variant annotation is the process of assigning functional information to the DNA variants identified in step 3. This implies the classification of variants accordi ...
Albinism - xy-zoo
Albinism - xy-zoo

DNA notes 2015 - OG
DNA notes 2015 - OG

... An insertion mutation is when a nitrogen base is added to the existing DNA A deletion mutation is when a nitrogen base is subtracted from the DNA A substitution mutation is when one nitrogen base is put in place of another. If our DNA was AATTGGCC An insertion would be AATTAGGCC A deletion would be ...
CHAPTER 12
CHAPTER 12

... during telophase, vesicles derived from the Golgi apparatus move along microtubules to the middle of the cell where they coalesce, producing a cell plate ...
File
File

... (a) The lac operon would always be turned on because the repressor cannot turn it off by binding to the operator. (b) Same as (a). (c) The operon would be uninducible. The repressor would remain bound to the operator even in the presence of the inducer. (d) The operon would be transcribed only weakl ...
Early Detection of Cancer Using Circulating Tumour DNA: Feasibility
Early Detection of Cancer Using Circulating Tumour DNA: Feasibility

... lineage will be shared by all or most DFTD tumours (Figure B); ctDNA assays to detect these mutations would thus be universal to DFTD. Early diagnosis of DFTD would not only assist with Tasmanian devil quarantine and conservation management, but would also provide tools to estimate the DFTD incubati ...
Standardization of pedigree collection
Standardization of pedigree collection

... identified whose alleles can either increase or decrease the risk of AD  There are certainly other genes which are to be identified ...
Phylogenetics Topic 2: Phylogenetic and genealogical homology
Phylogenetics Topic 2: Phylogenetic and genealogical homology

... two DNA sequences. In such cases they are referring to the percentage of nucleotide sites that are the same between the two sequences. There is considerable potential for misunderstanding because they are usually willing to assume that the entire set of DNA sequences have a single evolutionary origi ...
Lab 9: Regulation of lactose metabolism
Lab 9: Regulation of lactose metabolism

... The lac operon system thus far described shows negative control that is inducible by the substrate, lactose. There is also a positive control system operating in the lac operon. Maximal induction of the lac operon also requires the CAP- cAMP (catabolite activator protein complexed with cyclic adeno ...
Study Guide
Study Guide

... trisomic; those that have received just one copy of a chromosome are said to be monosomic for the chromosome.  Fig 15.12 shows non-disjunction. This leads to trisomy of which the most common example is Down’s syndrome (an aneuploid condition-chromosome 21). You should understand how this happens.  ...
Chance and Necessity in the Selection of Nucleic Acid Catalysts
Chance and Necessity in the Selection of Nucleic Acid Catalysts

... ter- and intramolecular pericyclic reactions22,24 have been isolated, but none have exhibited catalytic activity. In the one successful application of this approach, Prudent et al.25 selected for aptamers to a planar phenanthrene derivative designed as a transition state analogue for the slow isomer ...
No Slide Title
No Slide Title

... [1] Entrez Gene with RefSeq Entrez Gene is a great starting point: it collects key information on each gene/protein from major databases. It covers all major organisms. RefSeq provides a curated, optimal accession number for each DNA (NM_006744) or protein (NP_007635) ...
Document
Document

... The globin gene family = two clusters of loci coding for component subunits of hemoglobin: α-like cluster on chromosome 16 includes 3 functional loci β-like cluster on chromosome 11 includes 5 functional loci • Each locus codes for a polypeptide (protein subunit) of hemoglobin. • Two of the protein ...
Structure, expression and chromosomal localization of human p80
Structure, expression and chromosomal localization of human p80

... pseudogene for p80-coilin (2,224nt, lower case) shown here were submined to GenBank/EMBL under accession numbers U06632 and L06522 respectively. For the full-length mRNA, an in-frame stop codon TGA in the 5' noncoding sequence is underlined. The short arrow (nucleotide 535) shows the 5 ' end of the ...
ExtendToOtherGenes - The Breast Cancer Surgeon
ExtendToOtherGenes - The Breast Cancer Surgeon

... are possible the patient might only see 20 or 30 of those questions. For example, if a patient denies heart disease in the family, several questions about which relatives have heart disease will not be seen by the patient. Or if a patient has never taken hormone replacement therapy, questions about ...
function Complex genomic rearrangements lead to novel primate gene
function Complex genomic rearrangements lead to novel primate gene

... distinctiveness is difficult to quantify, here we mean functional divergence beyond differences in tissue expression or substrate specificity. Identification of such lineage-specific duplications would imply a simple strategy to identify recently evolved functions. In order to apply this strategy to ...
Genetics test vocabulary Review Name: Class: ______ 1. Gregor
Genetics test vocabulary Review Name: Class: ______ 1. Gregor

... 7. The study of heredity: _____genetics____________ 8. An alternate form of a gene: ____allele__________ 9. Having non identical alleles (not pure; ex. Aa): __heterozygous___ 10. Having identical alleles (pure, ex. AA): _homozygous_________ 11. Square used to determine probability and results of cro ...
Linked___Genes
Linked___Genes

... If crossing over occurs in maternal meiosis, there is no change, as the alleles are the same on each. HOWEVER, if there is crossing over in the paternal chromosomes, and the G/g alleles swap places, there will be ...
Screening for the Lynch Syndrome
Screening for the Lynch Syndrome

... : expansion or contraction of short repeated DNA sequences that are caused by the insertion or deletion of repeated unit : the presence of MSI -> defect in a DNA mismatch repair gene : hallmark of the Lynch syndrome (>90 % of tumors) ...
Primer on Comparative Genomics in PLoS
Primer on Comparative Genomics in PLoS

... and D the most distantly related pairs. Examples of the types of questions that can be addressed by comparisons between genomes at the different distances are given in the boxes. ...
Catastrophic Epilepsy of Infancy
Catastrophic Epilepsy of Infancy

... that happened by chance in the single generation • (less than, because some of those “chance” mutations will still be deleterious, and therefore should be subtracted from the total) • If the clinical symptoms are compatible, such a result is accepted as sufficient evidence of causality • (compare wi ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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