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Mitochondrial genes in the colourless alga Prototheca wickerhamii
Mitochondrial genes in the colourless alga Prototheca wickerhamii

... indicated by its bootstrap values (all above 93%). Consistent results were obtained by using informative positions varying in numbers between 453 and 98 or by applying further algorithms like a maximum likelihood approach and a neighbour-joining method (35). Two main aspects of the presented tree ca ...
No Slide Title
No Slide Title

... transcribed chromatin – Increasing histone acetylation can turn on some genes. – Immunoprecipitation of DNA cross-linked to chromatin with antibodies against Ac-histones enriches for actively transcribed genes. ...
gabi - beet: the german sugar beet genome - assbt
gabi - beet: the german sugar beet genome - assbt

Genetic Testing Guide - Clinpath Laboratories
Genetic Testing Guide - Clinpath Laboratories

... Cost of genetic tests Genetic testing is a highly specialised field of medicine. Most genetic tests are extremely comprehensive and require significant involvement and interpretation from pathologists and scientists. They also rely on expensive new technology. The costs for genetic tests are frequen ...
Microarrays and Cancer - URMC
Microarrays and Cancer - URMC

... expressed (turned on) in different cells under different conditions. When a gene is expressed, the genetic instructions coded in its DNA are transcribed (copied) to make messenger RNA (mRNA) molecules; then the coded instructions in messenger RNA are translated by the ribosome to make a specific pro ...
IBD Estimation in Pedigrees - Institute for Behavioral Genetics
IBD Estimation in Pedigrees - Institute for Behavioral Genetics

... shared Genes (G = A + D) ...
Module 4: The Role of Genes in Cancer
Module 4: The Role of Genes in Cancer

... broken chromosomes. It is also crucial that reproductive cells, such as eggs and sperm, contain the right number of chromosomes and that those chromosomes have the correct structure. If not, the offspring may not develop properly, such as people with Down Syndrome. People with Down syndrome have thr ...
Genesis and the Genome: Genomics Evidence for Human
Genesis and the Genome: Genomics Evidence for Human

... that the spatial organization of those genes is also similar. In short, organisms thought to be close evolutionary relatives have their genes in essentially the same order, with small differences arising from known mechanisms such as sequence inversions, translocations, and chromosome fusion events. ...
Gene mapping today: applications to farm animals
Gene mapping today: applications to farm animals

... loop as a whole may be in a potentially active or repressed transcriptional state. There may be one or several transcription units in a loop. The organizer (ORG) is a DNA sequence that binds a transcription factor whose presence is required for assembly of active chromatin. The hypothesis has been a ...
Entry PTX4 Evolution of the Pentraxin Family
Entry PTX4 Evolution of the Pentraxin Family

... Biosystems). The following primers were designed with Primer Express software (Applied Biosystems): mouse pentraxin (mPTX)3 (sense, 59-ACGAAATAGACAATGGACTTCATCC-39, antisense, 59-AGTCGCATGGCGTGGG-39); mPTX4 (sense, 59-TCATCAAGCAGCCCCACC39, antisense, 59-TTGCAAATGTTTCCTGGTCCT-39); b-actin (sense, 59T ...
gene addition
gene addition

... • Genes are the basic physical and functional units of heredity. • Genes are specific sequences of bases that encode instructions on how to make proteins. • It’s these proteins that perform most life functions and even make up the majority of cellular structures, not the genes ...
Mesoderm induction
Mesoderm induction

JNK1 plays an important part in this process provides an
JNK1 plays an important part in this process provides an

... Update ...
The UCSC Known Genes
The UCSC Known Genes

... proteins were not available. Hence we decided to develop an automated process to construct the UCSC Known Genes dataset based on the latest protein data from Swiss-Prot/TrEMBL (Bairoch et al., 2005), now also known as UniProt, and the associated mRNA data from GenBank (Benson et al., 2005). While th ...
The Nucleotide and Derived Amino Acid
The Nucleotide and Derived Amino Acid

... analysis, and examination by agarose gel electrophoresis (14) indicated that the insertsizes ranged from -300 to 1100 base pairs in length. The DNAs from six of these candidates were examined further by hybridization selection and translation (19) of human intestine mRNA. In each case, the hybridiza ...
(PSTVd) Infection
(PSTVd) Infection

... which show increased (2 fold) or decreased (0.5 fold) expression levels were identified (pvalue 0.05) and can be found in S1 Table. As expected, upon viroid infection many genes (1226 genes) showed altered expression. In early leaf samples the majority of genes (268 genes) which show differential ...
The connection between transcription and genomic instability
The connection between transcription and genomic instability

... region more susceptible to attack by internal metabolites that are reactive with ssDNA, leading to both mutagenic and recombinogenic lesions. This hypothesis has the advantage that it can also explain TAM, even though more quantitative data are lacking on TAM to strengthen this possibility. In addit ...
DNA Microarrays (Gene Chips) and Cancer - URMC
DNA Microarrays (Gene Chips) and Cancer - URMC

... expressed (turned on) in different cells under different conditions. When a gene is expressed, the genetic instructions coded in its DNA are transcribed (copied) to make messenger RNA (mRNA) molecules; then the coded instructions in messenger RNA are translated by the ribosome to make a specific pro ...
study
study

... complex modes of expression we used an additional analysis approach, which is more sensitive to such cases. This analysis uncovered 241 additional genes in nonmammary gland tissues that were clearly not detected in the first approach (see “Methods” and Additional file 10: Table S3, supplementary res ...
Reductive evolution of resident genomes
Reductive evolution of resident genomes

... appearing entirely from the eukaryotic cells2. On the other hand, the bacterium may become an compensatory back-mutations is low7. obligate parasite that offers no benefits to the host. Because of their obligate intracellular lifestyles, Thus, the fates of the host cell and the parasite are not ther ...
New Phytologist Supporting Information Notes S1  Populus trichocarpa
New Phytologist Supporting Information Notes S1 Populus trichocarpa

... and 831 million young leaf reads aligned to the reference transcriptome (Table A). Gene expression values were estimated using the latest publically available genome sequences and annotated ...
A new genetic screening test for Marfan syndrome
A new genetic screening test for Marfan syndrome

... Diagnosis and Indication Individuals affected with MFS are usually tall and slender with elongated fingers and toes and other skeletal abnormalities. The most common cardiovascular complication in MFS patients is progressive aortic root dilatation. Ascending aortic aneurysm can precipitate acute typ ...
11-3 - Cloudfront.net
11-3 - Cloudfront.net

... and distributed to gametes independently of one another ...
primer on genetic epidemiology
primer on genetic epidemiology

... developed for quantitative traits may be applied [29, 30] Although the assumptions underlying the twin and adoption studies are not always met in practice, many important findings have been discovered from such designs [31]. Structural equation models have been used to estimate heritability with con ...
Novel recessive BFSP2 and PITX3 mutations: Insights into
Novel recessive BFSP2 and PITX3 mutations: Insights into

... Similarly, PITX3, which is known for its pivotal role in the normal formation of the lens vesicle and separation from the lens ectoderm, is only known to cause ASD dominantly in humans. Three mutations have been reported to date in this transcription factor, but the pathogenic mechanism of the mutat ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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