Solid Tumour Section Liver: Intrahepatic cholangiocarcinoma Atlas of Genetics and Cytogenetics
... anatomical location and growth pattern. Biliary obstructive symptoms are rare. Generally, early stages of intrahepatic cholangiocarcinoma do not produce specific clinical symptoms that are recognized by affected persons, and there is no specific or practical laboratory method for the diagnosis in ea ...
... anatomical location and growth pattern. Biliary obstructive symptoms are rare. Generally, early stages of intrahepatic cholangiocarcinoma do not produce specific clinical symptoms that are recognized by affected persons, and there is no specific or practical laboratory method for the diagnosis in ea ...
The biased nucleotide composition of the HIV genome: a constant
... O (35%, Table 1). Group N and P viruses appear to contain slightly higher (group N) or lower (group P) levels of A-nucleotides, but only one (group P) or no (group N) full-length genomes with long terminal repeats (LTRs) are available for these groups (Table 1). As the LTR is relatively A-poor [5], ...
... O (35%, Table 1). Group N and P viruses appear to contain slightly higher (group N) or lower (group P) levels of A-nucleotides, but only one (group P) or no (group N) full-length genomes with long terminal repeats (LTRs) are available for these groups (Table 1). As the LTR is relatively A-poor [5], ...
The Process of How COMT Genetic Variants Provide the
... programming units of DNA like the 1s and 0s in computer binary code. These base pairs are almost exactly the same in all humans; however, there is one single base pair in the COMT gene that commonly differs among individuals. This single base pair out of the 20 million base pairs in the gene may det ...
... programming units of DNA like the 1s and 0s in computer binary code. These base pairs are almost exactly the same in all humans; however, there is one single base pair in the COMT gene that commonly differs among individuals. This single base pair out of the 20 million base pairs in the gene may det ...
Medical Genetics
... considered to have the same HLA types and the allele they represented would be given a number, such as B27 in the class I HLA-B locus or DR3 in the class II DR locus. As the genes responsible for encoding the class I and class II MHC chains were identified and sequenced, single HLA alleles initial ...
... considered to have the same HLA types and the allele they represented would be given a number, such as B27 in the class I HLA-B locus or DR3 in the class II DR locus. As the genes responsible for encoding the class I and class II MHC chains were identified and sequenced, single HLA alleles initial ...
Survey of Conserved Alternative Splicing Events
... The serine/arginine-rich (SR) protein family plays an important role in constitutive and alternative splicing (AS). These proteins regulate AS in a tissue-specific and stress-responsive manner. Pre-mRNAs encoding SR proteins are often alternatively spliced, and these AS events may be important for t ...
... The serine/arginine-rich (SR) protein family plays an important role in constitutive and alternative splicing (AS). These proteins regulate AS in a tissue-specific and stress-responsive manner. Pre-mRNAs encoding SR proteins are often alternatively spliced, and these AS events may be important for t ...
Leukaemia Section t(2;3)(p21;q26) THADA/MECOM Atlas of Genetics and Cytogenetics in Oncology and Haematology
... domain between the two sets of zinc fingers, and an acidic domain at its C-term. ...
... domain between the two sets of zinc fingers, and an acidic domain at its C-term. ...
Genomic and Proteomic Analysis of Mitochondrial Carrier Proteins
... and animal counterparts, but it is unclear which genes are expressed and which gene products are targeted to mitochondria. We (Millar et al., 2001) and others (Kruft et al., 2001) have recently presented proteomes of Arabidopsis mitochondria based on two-dimensional gel separations, but mitochondria ...
... and animal counterparts, but it is unclear which genes are expressed and which gene products are targeted to mitochondria. We (Millar et al., 2001) and others (Kruft et al., 2001) have recently presented proteomes of Arabidopsis mitochondria based on two-dimensional gel separations, but mitochondria ...
apgenetics1206 - cloudfront.net
... alleles black (B) and white (B’) for feather color show partial dominance, B/B’ individuals having “blue” feathers. If birds heterozygous for both alleles are mated, what proportion of the offspring is expected to white-feathered and pea-combed? 10) In a P cross, an A/A B/B C/C individual is paired ...
... alleles black (B) and white (B’) for feather color show partial dominance, B/B’ individuals having “blue” feathers. If birds heterozygous for both alleles are mated, what proportion of the offspring is expected to white-feathered and pea-combed? 10) In a P cross, an A/A B/B C/C individual is paired ...
Epigenetics in mood disorders
... defeated mice, the observed histone and HDAC modifications with imipramine treatment occurred only in the context of social defeat stress. The data provide a new explanation for the delayed onset of action of antidepressants in the treatment of depression. It should be noted that an observed increas ...
... defeated mice, the observed histone and HDAC modifications with imipramine treatment occurred only in the context of social defeat stress. The data provide a new explanation for the delayed onset of action of antidepressants in the treatment of depression. It should be noted that an observed increas ...
"sample" problems
... 1. Dwarfism is dominant, so a person only needs one gene to be a dwarf. We are told the person is homozygous so their genotype is DD. A normally-heighted person would be dd. The resultant offspring would all receive one D gene from one parent and a d gene from the other and, thus, would all be heter ...
... 1. Dwarfism is dominant, so a person only needs one gene to be a dwarf. We are told the person is homozygous so their genotype is DD. A normally-heighted person would be dd. The resultant offspring would all receive one D gene from one parent and a d gene from the other and, thus, would all be heter ...
development and mature motor function The splicing
... The Rbfox proteins (Rbfox1, Rbfox2, and Rbfox3) regulate the alternative splicing of many important neuronal transcripts and have been implicated in a variety of neurological disorders. However, their roles in brain development and function are not well understood, in part due to redundancy in their ...
... The Rbfox proteins (Rbfox1, Rbfox2, and Rbfox3) regulate the alternative splicing of many important neuronal transcripts and have been implicated in a variety of neurological disorders. However, their roles in brain development and function are not well understood, in part due to redundancy in their ...
HL7 V2.5.1 Genetic Test Result Message
... genomic and healthcare IT data standards may use this guide to extend these standards for support of clinical sequencing. Users of this guide must be familiar with the details of HL7 message construction and processing. This guide is not intended to be a tutorial on that subject. ...
... genomic and healthcare IT data standards may use this guide to extend these standards for support of clinical sequencing. Users of this guide must be familiar with the details of HL7 message construction and processing. This guide is not intended to be a tutorial on that subject. ...
B-catenin
... insulin (green) and anti-sFRP (red in (f) and (g)) detects sFRP on islet cells only when sFRP has been added to the culture media. • sFRP exposure led to inhibition of β-catenin ((h) versus (i), quantitated in (j)) and c-myc ((k) versus (l), quantitated in (m)). • Error bars = mean +/−s.e.m. ∗P < .0 ...
... insulin (green) and anti-sFRP (red in (f) and (g)) detects sFRP on islet cells only when sFRP has been added to the culture media. • sFRP exposure led to inhibition of β-catenin ((h) versus (i), quantitated in (j)) and c-myc ((k) versus (l), quantitated in (m)). • Error bars = mean +/−s.e.m. ∗P < .0 ...
Ch 15
... If a sex-linked trait is due to a recessive allele, a female will express this phenotype only if she is homozygous. Heterozygous females are carriers for the recessive trait. Because males have only one X chromosome (hemizygous), any male receiving the recessive allele from his mother will expre ...
... If a sex-linked trait is due to a recessive allele, a female will express this phenotype only if she is homozygous. Heterozygous females are carriers for the recessive trait. Because males have only one X chromosome (hemizygous), any male receiving the recessive allele from his mother will expre ...
Chronodisruption, cell cycle checkpoints and DNA repair
... meta-analyses and evidence showing that night work does play a role in breast cancer42,43. However, there are no clear indications for the exact pathway linking shift-work, chronodisruption and malignancy. Nocturnal light pulses entrain and synchronize the circadian clock and are long known to affec ...
... meta-analyses and evidence showing that night work does play a role in breast cancer42,43. However, there are no clear indications for the exact pathway linking shift-work, chronodisruption and malignancy. Nocturnal light pulses entrain and synchronize the circadian clock and are long known to affec ...
Altered cellular proliferation and mesoderm
... It has been suggested that the normal boundaries of Hox gene expression might normally be regulated by retinoic acid and that ectopic expression of the Hox genes induced by RA administration leads to morphological transformations (Kessel and Gruss, 1991; Conlon and Rossant, 1994). The recent identif ...
... It has been suggested that the normal boundaries of Hox gene expression might normally be regulated by retinoic acid and that ectopic expression of the Hox genes induced by RA administration leads to morphological transformations (Kessel and Gruss, 1991; Conlon and Rossant, 1994). The recent identif ...
Development of novel computational tools based on
... Two strains of bacteria of the same species can differ by as much as 30% of the accessory parts of their genomes (Sueoka, 1962). These differences mostly result from mechanisms such as: insertions, deletions, transpositions, duplications, recombinations and rearrangements of residues of mobile DNA s ...
... Two strains of bacteria of the same species can differ by as much as 30% of the accessory parts of their genomes (Sueoka, 1962). These differences mostly result from mechanisms such as: insertions, deletions, transpositions, duplications, recombinations and rearrangements of residues of mobile DNA s ...
TBK1 Gene Duplication and Normal
... NTG patients (0.62%) were found to carry TBK1 gene duplications, whereas no such mutations were identified in 1116 controls. TBK1 duplications have been detected in African American, white, and Asian NTG patients, suggesting that although these mutations are rare, they may be found worldwide. Moreov ...
... NTG patients (0.62%) were found to carry TBK1 gene duplications, whereas no such mutations were identified in 1116 controls. TBK1 duplications have been detected in African American, white, and Asian NTG patients, suggesting that although these mutations are rare, they may be found worldwide. Moreov ...
Robust gene silencing mediated by antisense small RNAs in the
... extensive transcriptome data sets are available and used to find genes that lacked expression under oxidative or nitrosative stress (32), heat shock (33), histone acetylation (34), DNA methylation (35) or tissue invasion (25,36). EHI_197520 had abundant sRNAs and low gene expression in the HM-1:IMSS ...
... extensive transcriptome data sets are available and used to find genes that lacked expression under oxidative or nitrosative stress (32), heat shock (33), histone acetylation (34), DNA methylation (35) or tissue invasion (25,36). EHI_197520 had abundant sRNAs and low gene expression in the HM-1:IMSS ...
Hypothesis testing at the extremes: fast and
... Over permutations, r is one-to-one with most standard trend statistics, which are described in terms of distributional assumptions for X and Y . A list of such standard statistics is given below, and Appendix B (see supplementary material available at Biostatistics online) provides citations and der ...
... Over permutations, r is one-to-one with most standard trend statistics, which are described in terms of distributional assumptions for X and Y . A list of such standard statistics is given below, and Appendix B (see supplementary material available at Biostatistics online) provides citations and der ...
Schizophrenia genetics: emerging themes for a complex disorder
... loci, we refer to regions of the genome that contains one or more allele that is associated with disorder at a level corresponding to genome-wide significance. However, because of linkage disequilibrium, typically, a region contains many strongly or partially correlated alleles, any of which might be ...
... loci, we refer to regions of the genome that contains one or more allele that is associated with disorder at a level corresponding to genome-wide significance. However, because of linkage disequilibrium, typically, a region contains many strongly or partially correlated alleles, any of which might be ...
Practice Questions, Lectures 6-13 (259 KB pdf file)
... c and c result in colored (c ) versus colorless (c) seeds, ...
... c and c result in colored (c ) versus colorless (c) seeds, ...
PPTX - Tandy Warnow
... • MetaPhyler, MetaPhlAn, and mOTU are marker-based techniques (but use different marker genes). ...
... • MetaPhyler, MetaPhlAn, and mOTU are marker-based techniques (but use different marker genes). ...
(a) (b)
... Scientific Inquiry • The first solid evidence associating a specific gene with a specific chromosome came from Thomas Hunt Morgan, an embryologist • Morgan’s experiments with fruit flies provided convincing evidence that chromosomes are the location of Mendel’s heritable factors ...
... Scientific Inquiry • The first solid evidence associating a specific gene with a specific chromosome came from Thomas Hunt Morgan, an embryologist • Morgan’s experiments with fruit flies provided convincing evidence that chromosomes are the location of Mendel’s heritable factors ...
Fungal cell wall chitinases and glucanases
... the 1,3-b-glucan chain is elongated and the gene encoding this enzyme is described as GEL1 for glucan elongating glucanosyltransferase (Mouyna et al., 2000a). GEL1 encodes a GPI-anchored protein homologous to the GAS1 and PHR gene products of S. cerevisiae and Ca. albicans, respectively. S. cerevisi ...
... the 1,3-b-glucan chain is elongated and the gene encoding this enzyme is described as GEL1 for glucan elongating glucanosyltransferase (Mouyna et al., 2000a). GEL1 encodes a GPI-anchored protein homologous to the GAS1 and PHR gene products of S. cerevisiae and Ca. albicans, respectively. S. cerevisi ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.