
Mapping the histone code at hMLH1. - JScholarship
... 2002). More recently, it was shown that induction of a heat shock gene displaces both H3.3 and H3, followed by selective deposition of H3.3 (Wirbelauer et al., 2005). When comparing histone tail modification profiles of H3 and H3.3, although none of the modifications examined were exclusive to eithe ...
... 2002). More recently, it was shown that induction of a heat shock gene displaces both H3.3 and H3, followed by selective deposition of H3.3 (Wirbelauer et al., 2005). When comparing histone tail modification profiles of H3 and H3.3, although none of the modifications examined were exclusive to eithe ...
Predicting_tRNA_and_tmRNA_genes_12-2-16
... In Summary: The phages that contain more than 1 tRNA within their genomes tend to localize the tRNAs to certain regions of the genomes (also called “tRNA clusters” in the phage tRNA literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from ...
... In Summary: The phages that contain more than 1 tRNA within their genomes tend to localize the tRNAs to certain regions of the genomes (also called “tRNA clusters” in the phage tRNA literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from ...
Chapter 4 PPT-VIEW
... Enzymes are biological, protein catalysts that increase the rate of a chemical reaction without being consumed by the reaction. • (They lower activation energy needed to start reactions). • Enzymes are globular proteins with specific shapes • Enzymes are specific for their substrate (i.e. the substa ...
... Enzymes are biological, protein catalysts that increase the rate of a chemical reaction without being consumed by the reaction. • (They lower activation energy needed to start reactions). • Enzymes are globular proteins with specific shapes • Enzymes are specific for their substrate (i.e. the substa ...
Predicting tRNA and tmRNA genes Aragorn - SEA
... In Summary: The phages that contain more than 1 tRNA within their genomes tend to localize the tRNAs to certain regions of the genomes (also called “tRNA clusters” in the phage tRNA literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from ...
... In Summary: The phages that contain more than 1 tRNA within their genomes tend to localize the tRNAs to certain regions of the genomes (also called “tRNA clusters” in the phage tRNA literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from ...
A Genome Scan for Eye Color in 502 Twin Families: Most Variation
... 199 pairs of adult twins and confirmed high correlations of .87 and .86 in male and female monozygotic (MZ) pairs respectively, with corresponding dizygotic (DZ) correlations of .26 and .43. However, they estimated the DZ opposite sex correlation at .69, which seems anomalously high, and therefore d ...
... 199 pairs of adult twins and confirmed high correlations of .87 and .86 in male and female monozygotic (MZ) pairs respectively, with corresponding dizygotic (DZ) correlations of .26 and .43. However, they estimated the DZ opposite sex correlation at .69, which seems anomalously high, and therefore d ...
Detection and identification of bacteria in clinical samples by 16S
... ethanol precipitation method to remove unincorporated reagents and ensure a neutral charge. Briefly, sequencing products were washed in 80 ml ethanol precipitation mix (3 ml NaAc, 62.5 ml 95 % ethanol and 14.5 ml water) and the DNA was pelleted by centrifugation (13 000 g, 15 min). The pellet was ag ...
... ethanol precipitation method to remove unincorporated reagents and ensure a neutral charge. Briefly, sequencing products were washed in 80 ml ethanol precipitation mix (3 ml NaAc, 62.5 ml 95 % ethanol and 14.5 ml water) and the DNA was pelleted by centrifugation (13 000 g, 15 min). The pellet was ag ...
Chromosomal
... Recombination Data: Scientific Inquiry • Alfred Sturtevant, one of Morgan’s students, constructed a genetic map, an ordered list of the genetic loci along a particular chromosome • Sturtevant predicted that the farther apart two genes are, the higher the probability that a crossover will occur betwe ...
... Recombination Data: Scientific Inquiry • Alfred Sturtevant, one of Morgan’s students, constructed a genetic map, an ordered list of the genetic loci along a particular chromosome • Sturtevant predicted that the farther apart two genes are, the higher the probability that a crossover will occur betwe ...
Regulation of transcript encoding the 43K
... Materials and methods). The sequence of the cDNA was determined and both the nucleic acid and deduced amino acid sequences were compared to that for the Torpedo 43K protein (Figs 1 and 2). Xen 43.1 cDNA is 1403 bp long, contains 205 bp of the 5' untranslated region and 1198 bp of protein-coding regi ...
... Materials and methods). The sequence of the cDNA was determined and both the nucleic acid and deduced amino acid sequences were compared to that for the Torpedo 43K protein (Figs 1 and 2). Xen 43.1 cDNA is 1403 bp long, contains 205 bp of the 5' untranslated region and 1198 bp of protein-coding regi ...
CTSC and PapillonLefvre syndrome: detection of recurrent
... or with the PLS phenotype (Hart et al. 2000b). Therefore, PLS, HMS, and AP1 are not different entities; they represent the phenotypic spectrum of a single disease. ...
... or with the PLS phenotype (Hart et al. 2000b). Therefore, PLS, HMS, and AP1 are not different entities; they represent the phenotypic spectrum of a single disease. ...
channel 1 gene dosage
... In mature mammalian muscle, the muscular chloride channel ClC-1 contributes about 75% of the sarcolemmal resting conductance (Gm). In mice carrying two defective alleles of the corresponding CIcl gene, chloride conductance (Gci) is reduced to less than 10 % of that of wild-type, and this causes hype ...
... In mature mammalian muscle, the muscular chloride channel ClC-1 contributes about 75% of the sarcolemmal resting conductance (Gm). In mice carrying two defective alleles of the corresponding CIcl gene, chloride conductance (Gci) is reduced to less than 10 % of that of wild-type, and this causes hype ...
papaya X-specific BACs monoica corresponding
... The papaya X-specific region showed marked expansion compared to the ancestral autosome in monoica. The monoica autosome expanded compared to the corresponding autosomal BAC in papaya, consistent with genome size differences. The expansion of the papaya X-specific region is largely due to the in ...
... The papaya X-specific region showed marked expansion compared to the ancestral autosome in monoica. The monoica autosome expanded compared to the corresponding autosomal BAC in papaya, consistent with genome size differences. The expansion of the papaya X-specific region is largely due to the in ...
Misidentification of a genomovar of Burkholderia cepacia by recA
... patterns with most of bands—for example, being concentrated in the 300–500 bp range in the case of the HaeIII digestion pattern. In addition, not all bands are of equal intensity, so that weaker bands may be missed, leading to the identification of the wrong genomovar type. It may be argued that the ...
... patterns with most of bands—for example, being concentrated in the 300–500 bp range in the case of the HaeIII digestion pattern. In addition, not all bands are of equal intensity, so that weaker bands may be missed, leading to the identification of the wrong genomovar type. It may be argued that the ...
Plant roots: new challenges in a changing world
... barley seedlings exposed to drought and after recovery using Methylation Sensitive Amplification Polymorphism Sequencing. The results showed evidence of methylation and demethylation in response to drought which was balanced in leaves but was dominated by methylation in roots where recovery to the p ...
... barley seedlings exposed to drought and after recovery using Methylation Sensitive Amplification Polymorphism Sequencing. The results showed evidence of methylation and demethylation in response to drought which was balanced in leaves but was dominated by methylation in roots where recovery to the p ...
Genetic Testing for Inherited Susceptibility to Colorectal Cancer
... papillary thyroid cancer, or multifocal/bilateral CHRPE, or between 10-20 adenomas; or 3. In first-degree relatives (e.g., siblings, parents, offspring) of patients diagnosed with FAP or AFAP. 4. Individuals with a known deleterious APC mutation in the family. E. Juvenile polyposis syndrome (JPS) 1. ...
... papillary thyroid cancer, or multifocal/bilateral CHRPE, or between 10-20 adenomas; or 3. In first-degree relatives (e.g., siblings, parents, offspring) of patients diagnosed with FAP or AFAP. 4. Individuals with a known deleterious APC mutation in the family. E. Juvenile polyposis syndrome (JPS) 1. ...
Genetic analysis of genes on the 4th chromosome of
... shows both the strength and weakness of old time genetics trying to disclose the nature of chromosome 4. To be able to see that chromosome 4 is acrocentric from the polytene chromosomes demands an enormous endurance, due to the small size of the left arm that almost always becomes embedded in the ch ...
... shows both the strength and weakness of old time genetics trying to disclose the nature of chromosome 4. To be able to see that chromosome 4 is acrocentric from the polytene chromosomes demands an enormous endurance, due to the small size of the left arm that almost always becomes embedded in the ch ...
Article Positive and Purifying Selection on the Drosophila Y
... male limited. These differences between the Y and the rest of the genome are likely to have profound consequences for the molecular evolution of Y-linked sequences as compared with the molecular evolution of sequences on the X and autosomes. In particular, the reduction in effective size of the Y re ...
... male limited. These differences between the Y and the rest of the genome are likely to have profound consequences for the molecular evolution of Y-linked sequences as compared with the molecular evolution of sequences on the X and autosomes. In particular, the reduction in effective size of the Y re ...
Quasispecies evolution of a hypervariable region of the feline
... Following inoculation of cat Oscar with FCV, virus was isolated from the oropharynx up to 39 days p.i. Comparison of the 2 day p.i. virus (Fig. 1 b) with the infecting isolate (5th passage LS015, Fig. 1 a) showed they were very similar, the 2 day p.i. virus containing one synonymous nucleotide subst ...
... Following inoculation of cat Oscar with FCV, virus was isolated from the oropharynx up to 39 days p.i. Comparison of the 2 day p.i. virus (Fig. 1 b) with the infecting isolate (5th passage LS015, Fig. 1 a) showed they were very similar, the 2 day p.i. virus containing one synonymous nucleotide subst ...
Neuroendocrine Gene Regulation in Hypothalamic Cell Lines
... have focused on immortalized cell models. One of the first fully differentiated immortalized hypothalamic cell lines is the gonadotropin-releasing hormone (GnRH)-secreting GT1 cells [12]. This cell line was created by directing tumorigenesis in GnRH-expressing neurons in transgenic mice using the 5’ ...
... have focused on immortalized cell models. One of the first fully differentiated immortalized hypothalamic cell lines is the gonadotropin-releasing hormone (GnRH)-secreting GT1 cells [12]. This cell line was created by directing tumorigenesis in GnRH-expressing neurons in transgenic mice using the 5’ ...
Fetal Hemoglobin Levels in Sickle Cell Disease and
... cannot distinguish females who were heterozygous for H and L alleles from females who were homozygous for the H allele. We can only deduce from this analysis that nonanemic individuals with greater than 3.3% F cells have at least one H allele. Phenotypes and genotypes of SS subjects. Due to preferen ...
... cannot distinguish females who were heterozygous for H and L alleles from females who were homozygous for the H allele. We can only deduce from this analysis that nonanemic individuals with greater than 3.3% F cells have at least one H allele. Phenotypes and genotypes of SS subjects. Due to preferen ...
Molecular insights into the causes of male infertility
... meaning that copy numbers of DAZ genes decide germcell number and acquisition of morphology and mobility (Reijo et al 1996a, b; Ruggiu et al 1997). Men lacking DAZ gene(s) may present with no germ cells, meiotic arrest, or simply fewer sperm (Reijo et al 1996a, b). Flies and mice, however, have auto ...
... meaning that copy numbers of DAZ genes decide germcell number and acquisition of morphology and mobility (Reijo et al 1996a, b; Ruggiu et al 1997). Men lacking DAZ gene(s) may present with no germ cells, meiotic arrest, or simply fewer sperm (Reijo et al 1996a, b). Flies and mice, however, have auto ...
Genetics Tutorial
... avoid doubling the number of chromosomes in each generation, cells must be created that carry only one set of chromosomes (haploid or 1n). ...
... avoid doubling the number of chromosomes in each generation, cells must be created that carry only one set of chromosomes (haploid or 1n). ...
Pairing of homologous regions in the mouse genome is associated
... translocations involving chromosome ends [10]. The likelihood of homologous pairing is also affected by the radial position of the chromosome which is in turn dependent of chromosome size, gene density, transcriptional activity and presence of nucleolus organiser regions (NORs) [11–14]. As an altern ...
... translocations involving chromosome ends [10]. The likelihood of homologous pairing is also affected by the radial position of the chromosome which is in turn dependent of chromosome size, gene density, transcriptional activity and presence of nucleolus organiser regions (NORs) [11–14]. As an altern ...
Lesson 1: Do you have good taste?
... Boreal Labs – Protein synthesis chalkboard model ‐ are a great (op onal) resource. To maintain the connec on to taste, gene, mRNA, and protein sequences of actual taste receptors can be used for student prac ce (Appendix II). 4) End by revisi ng the class discussion ques ons from the taste la ...
... Boreal Labs – Protein synthesis chalkboard model ‐ are a great (op onal) resource. To maintain the connec on to taste, gene, mRNA, and protein sequences of actual taste receptors can be used for student prac ce (Appendix II). 4) End by revisi ng the class discussion ques ons from the taste la ...
Genetics 7D
... copies of each gene. This is due to the fact that both mother and father contribute a copy at the time of conception. This original genetic material is copied each time a cell divides so that all cells contain the same DNA. Genes store the information needed for the cell to assemble proteins, which ...
... copies of each gene. This is due to the fact that both mother and father contribute a copy at the time of conception. This original genetic material is copied each time a cell divides so that all cells contain the same DNA. Genes store the information needed for the cell to assemble proteins, which ...
Name Class Date
... copies of each gene. This is due to the fact that both mother and father contribute a copy at the time of conception. This original genetic material is copied each time a cell divides so that all cells contain the same DNA. Genes store the information needed for the cell to assemble proteins, which ...
... copies of each gene. This is due to the fact that both mother and father contribute a copy at the time of conception. This original genetic material is copied each time a cell divides so that all cells contain the same DNA. Genes store the information needed for the cell to assemble proteins, which ...
RNA-Seq

RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.