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Gilbert - Blumberg Lab
Gilbert - Blumberg Lab

... -Cells can be good at accidentally fixing the damage due to errorprone DNA repair, limiting the ability to knock out all alleles ...
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... 2. Define transcription. 3. What is the full name of RNA? 4. What nucleotides are found in RNA? 5. Where in the eukaryotic cell does transcription take place? 6. What are the differences between DNA and RNA (include at least 3 differences)? 7. What are the differences between replication and transcr ...
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... a molecule on the cell surface or in the cell interior that has an affinity for a specific molecule (the ligand). ...
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... data as opposed to HOW to normalize data. I am including Background correction along with Normalizing here. • The pros and Cons of normalizing vs not. • What theoretically Normalizing is supposed to do and WHAT it actually does. ...
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(part of a “developmental reprogramming”). The roots of evolutionary

... Selector genes encode transcription factors. Ultrabithorax encodes a transcription factor that is normally expressed at high levels in T3 (as well as in the first abdominal segment) of Drosophila. Most selector genes, including Antp and Ubx, are homeobox genes Antp, Ubx, and a number of other select ...
Ch2. Genome Organization and Evolution
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... interactions on the hEx1 cDNA array. ...
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... sing at this point • If they do not hear the song of their species during the critical developmental period after birth they typically do not acquire the song * If they acquire a song it is usually abnormal ...
DNA Damage - Columbus Labs
DNA Damage - Columbus Labs

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High-dimensional Prognosis: Developing a gene signature from a
High-dimensional Prognosis: Developing a gene signature from a

The control of complexity in the human genome
The control of complexity in the human genome

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Slides - Celebrating the 20th anniversary of Swiss-Prot

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MicroRNA-330 acts as tumor suppressor and induces apoptosis of

... MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation Micro RNAs (miRNAs) are a class of small (B19–25nt), non coding regulatory RNAs that regulate gene expression by complementary base pairing with the 30-untran ...
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Szerkezetvizsgálati módszerek a biofizikában_2016_opt_mikr_1

... components. The plasmid must contain prokaryotic nucleotide sequences coding for a bacterial replication origin for DNA and an antibiotic resistance gene. These elements, often termed shuttle sequences, allow propagation and selection of the plasmid within a bacterial host to generate sufficient qua ...
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10DNAtoProt
10DNAtoProt

... B. splicing out of damaged DNA by DNA repair enzymes. C. joining of RNA from two different genes to form a new mRNA. D. the use of alternative reading frames when translating an mRNA. E. a new dance for people with alternative life styles. 9. During transcription of DNA to RNA: A. an RNA polymerase ...
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... 5. Much of the process of making an amino acid chain will be explained more fully in the next link, so we’ll leave the details of where and how an amino acid chain is built for later. How many amino acids are there, and what about them determines the nature of the protein being built? 6. If there ar ...
DNA Transcription / Translation
DNA Transcription / Translation

...  B. unwinds a strand of DNA.  C. binds to a strand of RNA.  D. attaches to the promoter sequence of a gene. ...
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Data Integration, Gene Ontology, and the Mouse*
Data Integration, Gene Ontology, and the Mouse*

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Chapter 14 2015 - Franklin College
Chapter 14 2015 - Franklin College

... B. Splicing out introns is a risky business (what if it’s done incorrectly) C. With these disadvantages, there must be an advantage or natural selection would not favor this arrangement ...
hinv1
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... • Addition of disease-summary type wet data (e.g. exp profiling on pooled samples) • Link with disease-specific DBs – Disease-originated/ oriented research • Tools for: Dis→Genes →Best annotation in the world (strength/mission of main body) • Tools for: Dis→Genes →Relationship with other phenotypes ...
Molecular Diagnosis Of Infectious Diseases
Molecular Diagnosis Of Infectious Diseases

...  For a positive result, repeat it again or repeat it with a different genomic locus  False-positive specimens can occur with poorly designed primers  A negative result from an infected patient could be due to the presence of PCR inhibitors that co-purify with RNA, a poor quality specimen, or a sp ...
A method for paralogy trees reconstruction
A method for paralogy trees reconstruction

... Genes belonging to the same organism are called paralogs when they show a significant similarity in the sequences, even if they have a different biological function. It is an emergent biological paradigm that the families of paralogs derive from a mechanism of gene duplication with modification, rep ...
Cloning of the mouse BTG3 gene and definition of a new
Cloning of the mouse BTG3 gene and definition of a new

... evolutionarily conserved and zoo-blot analysis using a mouse probe shows that sequences homologous to BTG3 could be detected in human using normal stringency condition (data not shown). Northern blot analysis revealed that BTG3 expression is ubiquitous, a specific 1.6 kb transcript (size in accordan ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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