Albinism, at (Mueller and Hutt, ii). This is an imperfect
... albinos, particularly in the double-recessive (cross-over) class, but not more than could have occurred by chance. (ii) Wit/i K. The four males found in 1953 to carry s/i also proved to be heterozygous for K and /c. As these matings were made on only a limited scale, comparatively few female offspri ...
... albinos, particularly in the double-recessive (cross-over) class, but not more than could have occurred by chance. (ii) Wit/i K. The four males found in 1953 to carry s/i also proved to be heterozygous for K and /c. As these matings were made on only a limited scale, comparatively few female offspri ...
Genomics Reveal Ancient Forms of Stanniocalcin in Amphioxus and
... Synopsis Stanniocalcin (STC) is present throughout vertebrates, including humans, but a structure for STC has not been identified in animals that evolved before bony fish. The origin of this pleiotropic hormone known to regulate calcium is not clear. In the present study, we have cloned three stanni ...
... Synopsis Stanniocalcin (STC) is present throughout vertebrates, including humans, but a structure for STC has not been identified in animals that evolved before bony fish. The origin of this pleiotropic hormone known to regulate calcium is not clear. In the present study, we have cloned three stanni ...
Full text - PAHdb - McGill University
... www.pahdb.mcgill.ca). It records and annotates both pathogenic alleles (n = 439, putative diseasecausing) and benign alleles (n = 41, putative untranslated polymorphisms) at the human phenylalanine hydroxylase locus (symbol PAH). Human alleles named by nucleotide number (systematic names) and their ...
... www.pahdb.mcgill.ca). It records and annotates both pathogenic alleles (n = 439, putative diseasecausing) and benign alleles (n = 41, putative untranslated polymorphisms) at the human phenylalanine hydroxylase locus (symbol PAH). Human alleles named by nucleotide number (systematic names) and their ...
Chapter 8
... Transcription in Prokaryotes • Synthesis of a complementary mRNA strand from a DNA template • Transcription begins when RNA polymerase binds to the promoter sequence on DNA • Transcription proceeds in the 5' 3' direction; only one of the two DNA strands is transcribed • Transcription stops when i ...
... Transcription in Prokaryotes • Synthesis of a complementary mRNA strand from a DNA template • Transcription begins when RNA polymerase binds to the promoter sequence on DNA • Transcription proceeds in the 5' 3' direction; only one of the two DNA strands is transcribed • Transcription stops when i ...
Bethesda Guidelines and MSI Testing
... Raised possibility that DNA MMR deficient cells might be relatively resistant to some types of cytotoxic chemotherapy. *Carethers et al. J Clin Invest 98:199-206, 1996. Ribic et al. N Engl J Med 349:247-257, 2003. ...
... Raised possibility that DNA MMR deficient cells might be relatively resistant to some types of cytotoxic chemotherapy. *Carethers et al. J Clin Invest 98:199-206, 1996. Ribic et al. N Engl J Med 349:247-257, 2003. ...
Identification of Human Polymorphisms in the Phenylthio
... includes doing a blind taste test using the control and PTC strips (make sure the volunteers rinse their mouths out with water if they have just eaten anything). The success of the PCR reactions will be determined by gel electrophoresis on Day 2 of the project, and DNA from successful PCR reaction ...
... includes doing a blind taste test using the control and PTC strips (make sure the volunteers rinse their mouths out with water if they have just eaten anything). The success of the PCR reactions will be determined by gel electrophoresis on Day 2 of the project, and DNA from successful PCR reaction ...
Article Lateral Gene Transfer and Gene
... was 1) irreversibly inactivated during the preparation of cellular fractions and/or 2) it catalyzes a different reaction. Although we were not able to demonstrate this activity, all critical residues for substrate and cofactor binding are conserved in all four Mastigamoeba CIIs. Furthermore, homolog ...
... was 1) irreversibly inactivated during the preparation of cellular fractions and/or 2) it catalyzes a different reaction. Although we were not able to demonstrate this activity, all critical residues for substrate and cofactor binding are conserved in all four Mastigamoeba CIIs. Furthermore, homolog ...
1 X chromosome crossover formation and genome stability in
... xnd-1(ok709); LG IV, ced-3(n717); LG V, mys-1(n3681), him-5(ok1896). Some strains were provided by the Caenorhabditis Genetics Center. xnd-1(ok709) was outcrossed multiple times for these studies due to long-term maintenance problems of the strain. Double and triple mutants were generated using sta ...
... xnd-1(ok709); LG IV, ced-3(n717); LG V, mys-1(n3681), him-5(ok1896). Some strains were provided by the Caenorhabditis Genetics Center. xnd-1(ok709) was outcrossed multiple times for these studies due to long-term maintenance problems of the strain. Double and triple mutants were generated using sta ...
Antigenic diversity of Theileria major piroplasm surface protein gene
... isolates were type I, and the cattle exhibited severe symptoms [5]. In our study, type I was rare (6 of 35); most of the isolates were types C (20 of 35) and B (17 of 35), and all cattle were normal clinically and on hematological examination. In this study, we used PCR-RLFP to subclassify type B, a ...
... isolates were type I, and the cattle exhibited severe symptoms [5]. In our study, type I was rare (6 of 35); most of the isolates were types C (20 of 35) and B (17 of 35), and all cattle were normal clinically and on hematological examination. In this study, we used PCR-RLFP to subclassify type B, a ...
Leukaemia Section t(1;11)(p32;q23) Atlas of Genetics and Cytogenetics
... There was 12 male and 23 female patients (non significant: epsilon = 1.86, 0.07 < p < 0.06). However, while there was 8 male and 10 female patients in myeloid cases, there was only 3 male patients and 13 female patients with ALL (chi2 = 6.25 p < 0.02). Patients median age was 4 years (range 0-76 yea ...
... There was 12 male and 23 female patients (non significant: epsilon = 1.86, 0.07 < p < 0.06). However, while there was 8 male and 10 female patients in myeloid cases, there was only 3 male patients and 13 female patients with ALL (chi2 = 6.25 p < 0.02). Patients median age was 4 years (range 0-76 yea ...
Spatial restriction of AChR gene expression to
... examined the distribution of hGH in denervated muscle. Fig. 3 shows that hGH is concentrated at synaptic sites in muscle that was denervated for 4 days. Like hGH at normal synaptic sites, hGH at denervated synaptic sites is perinuclear and is apparently associated with the golgi apparatus. Because h ...
... examined the distribution of hGH in denervated muscle. Fig. 3 shows that hGH is concentrated at synaptic sites in muscle that was denervated for 4 days. Like hGH at normal synaptic sites, hGH at denervated synaptic sites is perinuclear and is apparently associated with the golgi apparatus. Because h ...
The Drosophila Tissue Polarity Gene inturned Functions Prior to
... Isolation of a collectionof in alleles: A collection of in euparal as described previously (ADLER et al. 1987) and examined under bright field optics. Unlessnoted otherwise, all 18 new in alleles was isolated (Table 1 ) . Ten of our new data reported in detail are from in hemizygotes, where the alle ...
... Isolation of a collectionof in alleles: A collection of in euparal as described previously (ADLER et al. 1987) and examined under bright field optics. Unlessnoted otherwise, all 18 new in alleles was isolated (Table 1 ) . Ten of our new data reported in detail are from in hemizygotes, where the alle ...
0 1 0 1 1 1 0 0 1 0
... – The entropy of a data set is given by - p log2(p) - (1 - p) log2(1 - p) where p is the fraction of examples that belong to class predisposed. – The information gain of the split is given by the entropy of the original data set minus the weighted sum of entropies of the two data sets resulting from ...
... – The entropy of a data set is given by - p log2(p) - (1 - p) log2(1 - p) where p is the fraction of examples that belong to class predisposed. – The information gain of the split is given by the entropy of the original data set minus the weighted sum of entropies of the two data sets resulting from ...
Quantifying the Slightly Deleterious Mutation Model of Molecular
... (plus short adjoining lengths of exon) sequences from two X-linked genes surveyed in Mus domesticus, with M. caroli used as an out-group for the divergence data (Nachman 1997). We only included two of the four genes surveyed because there is a correlation between nucleotide diversity and recombinati ...
... (plus short adjoining lengths of exon) sequences from two X-linked genes surveyed in Mus domesticus, with M. caroli used as an out-group for the divergence data (Nachman 1997). We only included two of the four genes surveyed because there is a correlation between nucleotide diversity and recombinati ...
Exclusion of PAX9 and MSX1 mutation in six families affected by
... and MSX1 have been associated with cancer development but have not been described the relation between this phenomenon and dental agenesis (51,52). Another study showed evidence that low levels of PAX9 expression, has effects on tooth morphogenesis and generates non-syndromic form of oligodontia in ...
... and MSX1 have been associated with cancer development but have not been described the relation between this phenomenon and dental agenesis (51,52). Another study showed evidence that low levels of PAX9 expression, has effects on tooth morphogenesis and generates non-syndromic form of oligodontia in ...
Gene Section JUND (proto-oncogene) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... JUND is a member of the JUN family of basic region leucine zipper (bZIP) DNA-binding proteins. Analysis of the protein expression levels demonstrated an opposite expression pattern between JUN and JUND. When cells entry into the G0 phase of the cell cycle by serum starvation, JUN level decreases and ...
... JUND is a member of the JUN family of basic region leucine zipper (bZIP) DNA-binding proteins. Analysis of the protein expression levels demonstrated an opposite expression pattern between JUN and JUND. When cells entry into the G0 phase of the cell cycle by serum starvation, JUN level decreases and ...
Gene Section E2F1 (E2F transcription factor 1) Atlas of Genetics and Cytogenetics
... various in vitro cellular systems and in vivo animal models that have been employed in order to study E2F1 function in cancer. Excess of E2F1 may promote proliferation, but at the same time it may also enhance apoptosis, and there are examples where overexpression or lack of E2F1 has both positive a ...
... various in vitro cellular systems and in vivo animal models that have been employed in order to study E2F1 function in cancer. Excess of E2F1 may promote proliferation, but at the same time it may also enhance apoptosis, and there are examples where overexpression or lack of E2F1 has both positive a ...
Mating-Type Genes From the Homothallic Fungus Sordaria
... macrospora genomic DNA and cosmid DNAs revealed that the cloned DNAs are not rearranged with respect to their true genomic organization and that the S. macrospora mating-type genes all have a single copy in the genome (data not shown). The deduced physical map of the genome in the mating-type region ...
... macrospora genomic DNA and cosmid DNAs revealed that the cloned DNAs are not rearranged with respect to their true genomic organization and that the S. macrospora mating-type genes all have a single copy in the genome (data not shown). The deduced physical map of the genome in the mating-type region ...
Identification and analysis of functional elements in 1% of the human
... • Considerable knowledge on NRSF has been accumulated from previous studies, which provides a set of true positives and negatives. • Yet there is still room to make new discoveries, as illustrated in the paper. • The DNA motif bound by NRSF (called NRSE) is long and well-specified. • There is a high ...
... • Considerable knowledge on NRSF has been accumulated from previous studies, which provides a set of true positives and negatives. • Yet there is still room to make new discoveries, as illustrated in the paper. • The DNA motif bound by NRSF (called NRSE) is long and well-specified. • There is a high ...
Genomic Research to Identify Novel Pathways in the Development
... time [14, 30]. As of June 2011, 951 GWASs have now been published in a wide range of disorders and traits (http://www .genome.gov/gwastudies/). 2.2. GWASs and AAA. In 2007, the field of genomic research was ignited by simultaneous publication of three GWASs of cardiovascular disease [31–33]. Each of ...
... time [14, 30]. As of June 2011, 951 GWASs have now been published in a wide range of disorders and traits (http://www .genome.gov/gwastudies/). 2.2. GWASs and AAA. In 2007, the field of genomic research was ignited by simultaneous publication of three GWASs of cardiovascular disease [31–33]. Each of ...
Chapter 10 - People Server at UNCW
... • DNA of the human genome which encodes protein is called the exome • However, this represents only a small part of the genome ...
... • DNA of the human genome which encodes protein is called the exome • However, this represents only a small part of the genome ...
Regulation of Bacterial Conjugation in Microaerobiosis by
... produce strict anaerobiosis; for this reason, the term ‘‘microaerobiosis’’ is used. Diethyl sulfate mutagenesis: Fifty microliters of diethyl sulfate (DES) were dissolved in 5 ml of liquid E medium without carbon source and kept at 37° during 10 min in a screw-capped tube. One hundred microliters of ...
... produce strict anaerobiosis; for this reason, the term ‘‘microaerobiosis’’ is used. Diethyl sulfate mutagenesis: Fifty microliters of diethyl sulfate (DES) were dissolved in 5 ml of liquid E medium without carbon source and kept at 37° during 10 min in a screw-capped tube. One hundred microliters of ...
Changes in DNA-binding activity of transcription factors in the
... prolactin and glucocorticoids, while repressed by progesterone. These features make mammary gland a good model for studying mechanisms of tissue- and stage-specific gene expression. The main step on which regulation of gene expression occurs is the initiation of transcription. Minimum requirement fo ...
... prolactin and glucocorticoids, while repressed by progesterone. These features make mammary gland a good model for studying mechanisms of tissue- and stage-specific gene expression. The main step on which regulation of gene expression occurs is the initiation of transcription. Minimum requirement fo ...
Time-Resolved Transcriptome Analysis of Bacillus subtilis
... subtilis gene expression patterns in response to amino acid mixtures availability have been performed by proteomics and transcriptomics [15]. In these studies, Casamino Acid (CAA), a mixture of amino acids and oligopeptides and constitutes a rich nitrogen source, were used. The products of CAA-regul ...
... subtilis gene expression patterns in response to amino acid mixtures availability have been performed by proteomics and transcriptomics [15]. In these studies, Casamino Acid (CAA), a mixture of amino acids and oligopeptides and constitutes a rich nitrogen source, were used. The products of CAA-regul ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.