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Winter 2015 Newsletter
Winter 2015 Newsletter

... system (via our white blood cells) will attack and eliminate 95-99% of many foreign invaders (i.e. toxins, parasites, viruses, pollutants, bacteria, etc.) that it comes into contact with each and every day. Our endocrine system (thyroid, adrenals, hypothalamus, pineal and pituitary glands) must deal ...
Epigenetic Regulation
Epigenetic Regulation

... *6). You find hypomethylation in a set of colon cancer samples. Currently, the chemotherapeutic regimens used to treat colon cancer are not tolerated well with numerous non-specific side effects. ...
ECU Burroughs Wellcome Lecturer to Discuss Genome Editing for Disease Treatment
ECU Burroughs Wellcome Lecturer to Discuss Genome Editing for Disease Treatment

... East Carolina University’s Department of Biology will host the Burroughs Wellcome Lecture on Oct. 17. Associate Chief of Pathology for Research at Massachusetts General Hospital and Associate Professor at Harvard Medical School Dr. J. Keith Joung will present, “Editing Genes to Understand and Treat ...
fJ3fi3 ‘g-~I)JG12 ~ . ~ JAN 61997
fJ3fi3 ‘g-~I)JG12 ~ . ~ JAN 61997

... Dear Dr. Whiting: This is in response to your letter of December 3, 1996 making a submission to the Food and Drug Administration (FDA) pursuant to section 403(r)(6) of the Federal Food, Drug, and Cosmetic Act (the act). Your label shows that you are making the following statement for your product, P ...
Details - EuFishBioMed
Details - EuFishBioMed

... Despite intensive research efforts, the genetic and molecular basis of myocardial disease, arrhythmias and congenital heart defects are still largely unknown. Therefore, we seek enthusiastic, highly motivated Researchers, who will join our research team working on the identification and characteriza ...
Molecular genetic testing
Molecular genetic testing

... – Secondary targets of 25 diseases – Total of 54 diseases should be included in NBS test panels Watson et al. Genet. Med. 2006; 8:1S-11S ...
Degnan_10032014
Degnan_10032014

... which regulate not only the core enzymes involved in synthesizing thiamine, but also its import. We are also using directional RNAseq to empirically identify novel RNAs in B. thetaiotaomicron and possible RNA binding proteins. In addition we are leveraging recent advances in sequencing and automatio ...
Genomics and museum specimens - Integrative Biology
Genomics and museum specimens - Integrative Biology

... the new director of this institution. The MVZ and many other natural history museums collectively offer a rich source of preserved material that is now amenable to genomic studies. We should remember that these samples are finite, that extraction of DNA from them is destructive and that they were co ...
2- Tropical Course Biochemistry
2- Tropical Course Biochemistry

... A1- Review importance, chemical structure and classification of carbohydrates, lipids, and proteins A2- Describe nucleotides, nucleic acids, genetic code and protein synthesis A3- Summarize DNA replication, transcription and post transcriptional modification of RNA. A4- Describe regulation of gene e ...
RESEARCH GROUP: Inflammatory Diseases Group, Northern
RESEARCH GROUP: Inflammatory Diseases Group, Northern

... Decision Trees and their ensemble will be used to develop a computational model for predicting patient outcomes. c. An independent treatment and response blinded cohort of rheumatoid arthritis patients, will have DNA (n=152*) genotyped by targeted sequencing/methylation assay for the presence/absenc ...
When humans first ventured out of Africa some 60000 years ago
When humans first ventured out of Africa some 60000 years ago

... When humans first ventured out of Africa some 60,000 years ago, they left genetic footprints still visible today. By mapping the appearance and frequency of genetic markers in modern peoples, we create a picture of when and where ancient humans moved around the world. These great migrations eventual ...
common disease
common disease

... Ng SB et al. Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nat Genet. 2010. PMID: 20711175 ...
full release - University Hospitals Newsroom
full release - University Hospitals Newsroom

... Senior faculty collaborators on the research team included Dr. Chak, Dr. Markowitz and Joseph Willis, MD, Vice-Chair of the Department of Pathology at UH and the School of Medicine. First author on the report is Helena Moinova, PhD, instructor in the Department of Medicine at the School of Medicine, ...
DNA Message Conversion Activity
DNA Message Conversion Activity

... What is all of that gibberish? That jumble of letters actually represents a secret message encoded by DNA. A message that you as a student will definitely be pleased to decode! This will teach you how to use the genetic code, gaining "hands-on" experience and seeing how a sequence of DNA bases trans ...
Genome variation informatics: SNP discovery, demographic
Genome variation informatics: SNP discovery, demographic

... determined a reference sequence of the human genome ...
ORLANDO BIOLOGY ~ LESSON PLANS Competencies for 21st
ORLANDO BIOLOGY ~ LESSON PLANS Competencies for 21st

...  That the processes of transcription and translation use the information from the DNA to make specific proteins.  That control of transcription is on the gene level and is affected by many factors such as the environment and the stage of life.  That a change (mutation) in the DNA sequence (such a ...
ParScore Scantrons for Lecture Tests Introduction to Microbiology Use Your Textbook Wisely
ParScore Scantrons for Lecture Tests Introduction to Microbiology Use Your Textbook Wisely

... ❚  Prokaryotes have DNA spread throughout cytoplasm ❚  Eukaryotes have DNA within a membrane bounded nucleus ...
What Is Biotechnology
What Is Biotechnology

... microorganisms used in the fermentation of beer to the most sophisticated application of gene therapy. The term covers applications that are old and new, familiar and strange, sophisticated and simple. Defined in this way, the term is almost too broad to be useful. One way of thinking about biotechn ...
Chapter 15
Chapter 15

... 1. It is thought that soon a pharmacist will take a patient’s genetic screening tests into account when prescribing a drug 2. DNA microarrays (DNA chips or gene chips), in which thousands of DNA molecules are placed on a small chip, can be scanned; genes found with a cDNA strand are amplified using ...
the right order of things: peeling the onion of
the right order of things: peeling the onion of

... which we can understand the whole story of a patient’s illnesses without discarding facts or findings that seem unrelated. The inevitable conclusion of systems medicine is that everything is related, and we ignore any detail at our peril. Functional medicine is an evolved clinical map that uses scien ...
Evolving Insights into the Laws of Nature for Biological Evolution
Evolving Insights into the Laws of Nature for Biological Evolution

... generations. Whereas the phage P1 genome is quite densely packed with essential genes for the production of infective P1 particles, the sites of insertion of individual bacterial IS elements showed a drastically nonrandom distribution. The most often encountered IS2 element obviously preferred to in ...
FALL 2015 SEMINAR SERIES
FALL 2015 SEMINAR SERIES

... SEMINAR SERIES Fridays at 4:10 p.m. (unless otherwise noted) in 1414 Molecular Biology Building ...
Genetic Screening for Alzheimer`s Disease
Genetic Screening for Alzheimer`s Disease

...  SNP = Single-Nucleotide Polymorphism  nsSNP = nonsynonymous SNP  Several SNPs present in the APOE gene that serve as biomarkers in exploring the genetic basis of AD  Research Goal: Identify deleterious nsSNPs associated with the APOE gene ...
Linkage Map Construction and Genetic Diversity Analysis based on
Linkage Map Construction and Genetic Diversity Analysis based on

... used for transcriptome sequencing. A total of 92,255 and 127,522 reads were generated, and clustered into 34,688 and 40,947 unigenes, respectively. 27 ESTs were found to have different expression between parental lines, and the most differentially expressed EST were known as Ankyrin repeat domain an ...
Genetic Engineering
Genetic Engineering

... inserted into a bacteria’s plasmid (a single ringed chromosome). This plasmid with the human insulin gene can then be used to produce insulin to treat certain forms of diabetes. This is one example of how genetic engineering techniques can be used to create pharmaceuticals or medicines. ...
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Personalized medicine

Personalized medicine or PM is a medical model that proposes the customization of healthcare - with medical decisions, practices, and/or products being tailored to the individual patient. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient’s genetic content or other molecular or cellular analysis. The use of genetic information has played a major role in certain aspects of personalized medicine (e.g. pharmacogenomics), and the term was first coined in the context of genetics, though it has since broadened to encompass all sorts of personalization measures.
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