• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Decreased
Decreased

... windshield washer fluid, etc.) is metabolized by alcohol dehydrogenase to formaldehyde and formic acid. Leads to metabolic acidosis and optic neuritis (from formate) that can cause blindness. • Treatment: Infuse EtOH to keep blood concentration at 100-200 mg/dL (legally intoxicated) for long enough ...
Efficient Phosphodiester Hydrolysis by
Efficient Phosphodiester Hydrolysis by

... model substrate BDNPP were monitored spectrophotometrically for the absorbance increase at 400 nm due to the formation of 2,4-dinitrophenolate over time, under conditions of excess complex at 25 °C, and the reaction mixtures were monitored until saturation was reached. In these experiments, all of t ...
Enzymes 1. All cells in multicellular organisms contain thousands of
Enzymes 1. All cells in multicellular organisms contain thousands of

... Enzymes help catalyze, or speed up, these chemical reactions by lowering the amount of activation energy needed for the reactions to proceed. Reactions that do not use an enzyme require more energy. 12. According to the chemical equation, water and oxygen are produced when hydrogen peroxide is broke ...
1 - Testbank Byte
1 - Testbank Byte

... 22. NAD+ and FAD are often referred to as a. redox proteins. b. polymers. c. reduced dinucleotides. d. electron-carrying coenzymes. e. all of the above Ans: d ...
AP Laboratory Investigation Lab 13 – Enzyme Activity 2H2O2
AP Laboratory Investigation Lab 13 – Enzyme Activity 2H2O2

... INTRODUCTION:  What  would  happen  to  your  cells  if  they  made  a  poisonous  chemical?  You  might  think  that  they   would  die.  In  fact,  your  cells  are  always  making  poisonous  chemicals.  They  do  not  die  because ...
Pattern Matching: Organic Molecules
Pattern Matching: Organic Molecules

... So far we have identified three of the four major classes of molecules in living things:  Proteins and their subunits amino acids,  Lipids including fats and oils with their subunits, fatty acids, and steroids,  Carbohydrates, including starch, cellulose, and glycogen with their subunits, sugars. ...
Pattern Matching: Organic Molecules
Pattern Matching: Organic Molecules

... So far we have identified three of the four major classes of molecules in living things:  Proteins and their subunits amino acids,  Lipids including fats and oils with their subunits, fatty acids, and steroids,  Carbohydrates, including starch, cellulose, and glycogen with their subunits, sugars. ...
Biology 162: Computational Genetics
Biology 162: Computational Genetics

... Extreme value problems • How to convert Sbit to an expect value? • Since alignment is not truly local, theory used for BLAST does not hold here • Solutions (both available in HMMER) – Conservative approximation valid for any profile – Empirically fit extreme value distribution using simulated seque ...
Test 9 Review - Evan`s Chemistry Corner
Test 9 Review - Evan`s Chemistry Corner

... the potential energy of the reactants and ΔH is positive. Catalysts reduce the activation energy but have no effect on the change in enthalpy. ...
Protein Interaction Analysis - Bio-Rad
Protein Interaction Analysis - Bio-Rad

... Even if a protein and its ligand exhibit strong binding affinity for each other and are expressed at sufficient levels in a particular tissue to interact functionally, other factors influence the nature of their interaction. Certain molecules, such as ions or cofactors, may be critical for binding, ...
Bioinformatics - Department of Computer Science
Bioinformatics - Department of Computer Science

... mathematics, computer science and statistics - this type of knowledge is becoming increasingly important in biology. ...
Rate of enzymatic reactions
Rate of enzymatic reactions

... molecules are present, more substrate molecules can be acted upon at the same time producing more products (providing that the substrate concentration is limitless). 4. Effect of PH:  The point where the enzyme is most active - is known as the optimum pH .Extremely high or low pH values generally r ...
Algorithmic Foundations of Computational Biology Spring 2017
Algorithmic Foundations of Computational Biology Spring 2017

... modeled biological problems. The algorithms are presetned together with their underlying data structures, mathematical analysis of their performace, and at times, the exciting story of the researchers quest for algorithm optimality (speed). The overall work in the class will help in providing an alg ...
Molecular Interactions in Cell events
Molecular Interactions in Cell events

... Activation occurs when trypsinogen has amino acids removed in the duodenum by another protease enzyme This changes the trypsinogen into the active form trypsin Trypsin then helps to activate more trypsinogen molecules ...
manual PURExpress In Vitro Protein Synthesis Kit E6800
manual PURExpress In Vitro Protein Synthesis Kit E6800

... Considerations for Template Preparation and Detection Methods: PCR products, linear, or circular plasmid DNA can be used as the template DNA with PURExpress. While higher yields are often obtained with circular plasmid DNA as the template, PCR products can generate acceptable yields and can provide ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Total ten models were generated against the template 3DT7. The best ranked model (Fig. 2) was then subjected for evaluation to check the quality of the generated model. There was more than 62 % sequence identity with E value 0.00e-1 in query and template sequences. Then MODELLER was used to generate ...
Gel-Filtration Chromatography - DORAS
Gel-Filtration Chromatography - DORAS

... molecules larger than the pores of the stationary phase matrix will be excluded from the internal volume within the beads. They will, therefore, migrate quite rapidly through the column, emerging at V0, whilst molecules smaller than the matrix pores (as well as those intermediate in size) will equil ...
Peterson et al., PNAS, 2000 - Randall T. Peterson Lab
Peterson et al., PNAS, 2000 - Randall T. Peterson Lab

... of 6 nM (ED50 ⬇ 2 nM), suggesting that it disrupts a specific developmental process at least 1,000 times more potently than it interferes with other visible developmental processes. Therefore, the potency of these compounds, their sensitivity to structural modification, and the apparent absence of ...
Guide to Chapter 17. Thermodynamics
Guide to Chapter 17. Thermodynamics

... Learning Objective 16: Determine the temperature where a chemical reaction or physical change is spontaneous or is not spontaneous. Learning Objective 17: Given the value of DHo and DSo for a chemical change or physical change, predict what change occurs in DGo if the temperature is increased or dec ...
Powerpoint
Powerpoint

... http://www.rcdc.nd.edu/RCDC/RadChemHomePage.html ...
Extract for Activity 9.14
Extract for Activity 9.14

... peroxide, a product of O2 dismutation, leading to the formation of reactive hydroxyl radicals which contribute to toxicity. In order to develop a SOD mimic for clinical use it is necessary to incorporate the metal in a suitable complex which has the required catalytic effect while showing low toxic ...
Genetically engineered gold-binding polypeptides
Genetically engineered gold-binding polypeptides

... of high salt concentrations, conditions under which other proteins do not exhibit gold binding [5, 7]. During the selection processes, it was found that the goldbinding polypeptides bind more strongly to gold after the surface is treated with HF to remove surface impurities, indicating that the GBPs ...
Student Questions and Answers October 15, 2002
Student Questions and Answers October 15, 2002

... under in vivo conditions. [As already illustrated by AG, the contents of cells and organelles represent a rather “thick soup”. This phenomenon has been called “macromolecular crowding”, since the total “concentration” of different macromolecules and their assemblies ranges from 20 up to 40% (w/v). M ...
2.3 Carbon-Based Molecules
2.3 Carbon-Based Molecules

... 2.3 Carbon-Based Molecules • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. – Amino acids are linked by peptide bonds. ...
Exam 3
Exam 3

... The last page of this exam contains equations, constants,and other information you might find useful. The exam consists of 34 questions worth 100 points plus 5 bonus points on a total of 13 pages. It will be scored out of 100 points, and you can receive a maximum of 100 point. ...
< 1 ... 65 66 67 68 69 70 71 72 73 ... 188 >

Multi-state modeling of biomolecules

Multi-state modeling of biomolecules refers to a series of techniques used to represent and compute the behaviour of biological molecules or complexes that can adopt a large number of possible functional states.Biological signaling systems often rely on complexes of biological macromolecules that can undergo several functionally significant modifications that are mutually compatible. Thus, they can exist in a very large number of functionally different states. Modeling such multi-state systems poses two problems: The problem of how to describe and specify a multi-state system (the ""specification problem"") and the problem of how to use a computer to simulate the progress of the system over time (the ""computation problem""). To address the specification problem, modelers have in recent years moved away from explicit specification of all possible states, and towards rule-based formalisms that allow for implicit model specification, including the κ-calculus, BioNetGen, the Allosteric Network Compiler and others. To tackle the computation problem, they have turned to particle-based methods that have in many cases proved more computationally efficient than population-based methods based on ordinary differential equations, partial differential equations, or the Gillespie stochastic simulation algorithm. Given current computing technology, particle-based methods are sometimes the only possible option. Particle-based simulators further fall into two categories: Non-spatial simulators such as StochSim, DYNSTOC, RuleMonkey, and NFSim and spatial simulators, including Meredys, SRSim and MCell. Modelers can thus choose from a variety of tools; the best choice depending on the particular problem. Development of faster and more powerful methods is ongoing, promising the ability to simulate ever more complex signaling processes in the future.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report