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... concentration gradient, aqueous solubility and film thickness on drug transport across the PVA films has been demonstrated in this study. These results highlight the potential to modify the rate of drug release from the GIRESTM system by altering these parameters and the ability to tailor the system ...
... concentration gradient, aqueous solubility and film thickness on drug transport across the PVA films has been demonstrated in this study. These results highlight the potential to modify the rate of drug release from the GIRESTM system by altering these parameters and the ability to tailor the system ...
1 Intro / Review : Chemical Kinetics
... Check Out: http://evillusion.files.wordpress.com/2008/01/krebs-citric-acid.jpg ...
... Check Out: http://evillusion.files.wordpress.com/2008/01/krebs-citric-acid.jpg ...
APEF – Equilibrium and Reaction Rate Multiple Choice Answers
... APEF – Equilibrium and Reaction Rate – Multiple Choice Questions - Answers - Page 1 of 6 ...
... APEF – Equilibrium and Reaction Rate – Multiple Choice Questions - Answers - Page 1 of 6 ...
Rapid Microwave Synthesis, Characterization and Reactivity
... function 1 in GSAS) was employed to model the background. The unit cell parameters, peak profile parameters and atomic parameters were refined subsequently. The peak shape was modelled using the pseudo-Voigt function (profile function 2 in GSAS). Constraints were applied to the thermal parameters of ...
... function 1 in GSAS) was employed to model the background. The unit cell parameters, peak profile parameters and atomic parameters were refined subsequently. The peak shape was modelled using the pseudo-Voigt function (profile function 2 in GSAS). Constraints were applied to the thermal parameters of ...
Structures of nucleotide-bound and free aIF2γ from Sulfolobus
... The α- and β-phosphates of GDP are located in the cavity limited by the main chain amide groups of the P-loop (residues 18-23), switch 2 (residues 96-97), hydroxyl group of Thr23 and the side chain of strictly conserved Lys22. It is interesting to note that most of the main chain amide groups of th ...
... The α- and β-phosphates of GDP are located in the cavity limited by the main chain amide groups of the P-loop (residues 18-23), switch 2 (residues 96-97), hydroxyl group of Thr23 and the side chain of strictly conserved Lys22. It is interesting to note that most of the main chain amide groups of th ...
Agent-based Protein Structure Prediction
... possibility is that of imposing rigid constraints (as done in [12]) directly in the simulation. Interactions between amino acids, on the other end, may be treated either considering their chemical and physical properties or using a statistical approach. One relevant problem is the correlation betwe ...
... possibility is that of imposing rigid constraints (as done in [12]) directly in the simulation. Interactions between amino acids, on the other end, may be treated either considering their chemical and physical properties or using a statistical approach. One relevant problem is the correlation betwe ...
Enzyme - Rubin Gulaboski
... a specific reaction • each enzyme needs to be the right shape for the job • enzymes are named for the reaction they help • sucrase breaks down sucrose • proteases breakdown proteins Oh, I get it! • lipases breakdown lipids They end in -ase • DNA polymerase builds DNA ...
... a specific reaction • each enzyme needs to be the right shape for the job • enzymes are named for the reaction they help • sucrase breaks down sucrose • proteases breakdown proteins Oh, I get it! • lipases breakdown lipids They end in -ase • DNA polymerase builds DNA ...
Lecture 6
... Myosin is a large asymmetric molecule, it has a long tail and two globular heads (Fig. M1). The tail is about 1,600 Å long and 20 Å wide. Each head is about 165 Å long, 65 Å wide and 40 Å deep at its thickest part. The molecular weight of myosin is about 500,000. In strong denaturing solutions, such ...
... Myosin is a large asymmetric molecule, it has a long tail and two globular heads (Fig. M1). The tail is about 1,600 Å long and 20 Å wide. Each head is about 165 Å long, 65 Å wide and 40 Å deep at its thickest part. The molecular weight of myosin is about 500,000. In strong denaturing solutions, such ...
Kinetic models of metabolism: model construction, model
... are inadequate and instead a kinetic modelling approach is necessary. Given the large number of reactions included in the network, a pipeline has been built to automatically generate kinetic laws from reaction stoichiometries. In this context a precise description of the reactional mechanism is impo ...
... are inadequate and instead a kinetic modelling approach is necessary. Given the large number of reactions included in the network, a pipeline has been built to automatically generate kinetic laws from reaction stoichiometries. In this context a precise description of the reactional mechanism is impo ...
1.1 Functional Groups of Biomolecules and their Reactions
... limits of application of the term” (IUPAC, Commission on Nomenclature of Organic Chemistry, 1993). Functional group reactivity may be changed by the presence of other neighbouring functional groups but usually behaves uniformly in every molecule where it can be found. There are several common functi ...
... limits of application of the term” (IUPAC, Commission on Nomenclature of Organic Chemistry, 1993). Functional group reactivity may be changed by the presence of other neighbouring functional groups but usually behaves uniformly in every molecule where it can be found. There are several common functi ...
2.3 Carbon-Based Molecules
... 2.3 Carbon-Based Molecules Four main types of carbon-based molecules are found in living things. • Carbohydrates are made of carbon, hydrogen, and oxygen. All carbohydrates exist in a ratio of 1 carbon: 2 ...
... 2.3 Carbon-Based Molecules Four main types of carbon-based molecules are found in living things. • Carbohydrates are made of carbon, hydrogen, and oxygen. All carbohydrates exist in a ratio of 1 carbon: 2 ...
Document
... • To cool down, it needs to absorb the extra heat that you have just put in. In the case we are looking at, the back reaction absorbs heat. The position of equilibrium therefore moves to the left. The new equilibrium mixture contains more A and B, and less C and D. ...
... • To cool down, it needs to absorb the extra heat that you have just put in. In the case we are looking at, the back reaction absorbs heat. The position of equilibrium therefore moves to the left. The new equilibrium mixture contains more A and B, and less C and D. ...
Build a Paper Model of Transfer RNA (tRNA)
... Make slits in-between each double line (16 total). Be careful not to cut through the entire strip. ...
... Make slits in-between each double line (16 total). Be careful not to cut through the entire strip. ...
ENZYMES
... • Enzymes are globular proteins. They have a complex tertiary and quaternary structure in which polypeptides are folded around each other to form a roughly spherical or globular shape. The overall 3D shape of an enzyme molecule is very important: if it is altered, the enzyme cannot bind to its subst ...
... • Enzymes are globular proteins. They have a complex tertiary and quaternary structure in which polypeptides are folded around each other to form a roughly spherical or globular shape. The overall 3D shape of an enzyme molecule is very important: if it is altered, the enzyme cannot bind to its subst ...
CHAPTER 4: Enzyme Structure
... biotin, FAD, NAD or coenzyme A). Many of these are derived from dietary vitamins, which is why they are so important. The complete active enzyme with its cofactor is called a holoenzyme, while just the protein part without its cofactor is called the apoenzyme. ...
... biotin, FAD, NAD or coenzyme A). Many of these are derived from dietary vitamins, which is why they are so important. The complete active enzyme with its cofactor is called a holoenzyme, while just the protein part without its cofactor is called the apoenzyme. ...
Bioenergetics and Metabolism
... Glycolysis is a central pathway that takes glucose generated by carbohydrate metabolism and converts it to pyruvate. Under aerobic conditions, the pyruvate is oxidized in the citrate cycle which generates reducing power for redox reactions in the electron transport system that result in ATP producti ...
... Glycolysis is a central pathway that takes glucose generated by carbohydrate metabolism and converts it to pyruvate. Under aerobic conditions, the pyruvate is oxidized in the citrate cycle which generates reducing power for redox reactions in the electron transport system that result in ATP producti ...
Topic: Developmental biology Extra
... other specialised subunits. Biochemical and histological assessments were used to assess the presence of these subunits at protein level. Results The C2 and d2 subunits were identified in olfactory epithelium, which is a known location of both the B1 and a4 subunits. The a4 subunit was found in seve ...
... other specialised subunits. Biochemical and histological assessments were used to assess the presence of these subunits at protein level. Results The C2 and d2 subunits were identified in olfactory epithelium, which is a known location of both the B1 and a4 subunits. The a4 subunit was found in seve ...
Why to develop a model by using NTCC calculus?
... 2. Hormone binding, usually to an extracellular domain of a 7-helix receptor (GPCR), causes a conformational change in the receptor that is transmitted to a G-protein on the cytosolic side of the membrane. The nucleotide-binding site on Ga becomes more accessible to the cytosol, where [GTP] > [GDP]. ...
... 2. Hormone binding, usually to an extracellular domain of a 7-helix receptor (GPCR), causes a conformational change in the receptor that is transmitted to a G-protein on the cytosolic side of the membrane. The nucleotide-binding site on Ga becomes more accessible to the cytosol, where [GTP] > [GDP]. ...
Thermodynamics of Micelle Formation
... performed a titration of CTAB (cetyltrimethylammonium bromide) into aqueous solution. Peaks 1 through 20 are endothermic and peaks 21 to 50 are exothermic (Fig. 3A). This data was unexpected as the titration data is opposite to that seen with SDS. It is not precisely known what accounts for this dif ...
... performed a titration of CTAB (cetyltrimethylammonium bromide) into aqueous solution. Peaks 1 through 20 are endothermic and peaks 21 to 50 are exothermic (Fig. 3A). This data was unexpected as the titration data is opposite to that seen with SDS. It is not precisely known what accounts for this dif ...
NAD + , NADP +
... dermatitis, diarrhea, and dementia, followed in many cases by death. Pellagra is still found among alcoholics, whose intestinal absorption of niacin is much reduced, and whose caloric needs are often met with distilled spirits that are virtually devoid of vitamins, including niacin. ...
... dermatitis, diarrhea, and dementia, followed in many cases by death. Pellagra is still found among alcoholics, whose intestinal absorption of niacin is much reduced, and whose caloric needs are often met with distilled spirits that are virtually devoid of vitamins, including niacin. ...
Metabolism: Citric acid cycle
... 23. The glyoxylate cycle in plants is performed in specialized peroxisomes, called glyoxisomes. The ATP equivalent for one NADH formed during the glyoxylate cycle is about 2.5. Starting with acetyl CoA, what is the approximate yield of high-energy phosphate bonds (net ATP formed) via the glyoxylate ...
... 23. The glyoxylate cycle in plants is performed in specialized peroxisomes, called glyoxisomes. The ATP equivalent for one NADH formed during the glyoxylate cycle is about 2.5. Starting with acetyl CoA, what is the approximate yield of high-energy phosphate bonds (net ATP formed) via the glyoxylate ...
modelling human energy conversion and metabolism
... The human physiological system is stressed to its limits during endurance sports competition events such as bicycle racing or marathon running. By computational modelling of the body during such challenging events, we can investigate adaptation under extreme stress, which is not only useful to under ...
... The human physiological system is stressed to its limits during endurance sports competition events such as bicycle racing or marathon running. By computational modelling of the body during such challenging events, we can investigate adaptation under extreme stress, which is not only useful to under ...
An Organometallic Inhibitor for Glycogen Synthase Kinase 3
... We envisioned that replacing the indolocarbazole alkaloid scaffold with metal complexes in which the structural features of the indolocarbazole aglycon 2a or the related arcyriaflavin A 2b are retained in one of the ligands would allow metal complexes to be targeted to the ATP-binding site of protei ...
... We envisioned that replacing the indolocarbazole alkaloid scaffold with metal complexes in which the structural features of the indolocarbazole aglycon 2a or the related arcyriaflavin A 2b are retained in one of the ligands would allow metal complexes to be targeted to the ATP-binding site of protei ...
Enzymes
... Enzymes are :a biological catalyst. Usually a globular protein molecule produced by living organisms that can speed up a specific chemical reaction without itself being destroyed or changed in any way. They are produced by the living organism and are usually present in only very small amounts in ...
... Enzymes are :a biological catalyst. Usually a globular protein molecule produced by living organisms that can speed up a specific chemical reaction without itself being destroyed or changed in any way. They are produced by the living organism and are usually present in only very small amounts in ...