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Cases of Metabolic Acidosis
Cases of Metabolic Acidosis

... now positive. What would you do? a) Start sodium bicarbonate b) Intubate the patient c) Both a) and b) d) Neither a) or b) ...
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... 3. Reaction kinetics, reactions of zero, first, and second order, activation energy, catalysers. Relationship between reaction kinetics and thermodynamics. 4. Dispersion systems, solutions, ways of expressing their composition (concentration). Activity and activity coefficient. Solubility of substan ...
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... (H) Proteins should comprise 10-25% of consumed Calories. 8 essential amino acids, difficult to obtain with vegetarian diets. Numerous and diverse functions, the last resort for energy provision. Metabolic use results in ketone production and excessive urea. (I) Micronutrients not for energy, no Ca ...
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Metabolic network modelling



Metabolic network reconstruction and simulation allows for an in-depth insight into the molecular mechanisms of a particular organism. In particular, these models correlate the genome with molecular physiology. A reconstruction breaks down metabolic pathways (such as glycolysis and the Citric acid cycle) into their respective reactions and enzymes, and analyzes them within the perspective of the entire network. In simplified terms, a reconstruction collects all of the relevant metabolic information of an organism and compiles it in a mathematical model. Validation and analysis of reconstructions can allow identification of key features of metabolism such as growth yield, resource distribution, network robustness, and gene essentiality. This knowledge can then be applied to create novel biotechnology.In general, the process to build a reconstruction is as follows: Draft a reconstruction Refine the model Convert model into a mathematical/computational representation Evaluate and debug model through experimentation↑
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