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Unit 8 Communicable Diseases
Unit 8 Communicable Diseases

... Your immune system has a memory of every antigen it has encountered. Active Immunity develops naturally and artificially. Vaccinations are prepared dead or weakened pathogens that are introduced into the body to stimulate an immune response. ...
Figure 14-10 - University of Belgrade
Figure 14-10 - University of Belgrade

... Tumor antigens • Tumor-specific antigens (TSA) Antigens expressed on tumor cells but not on normal cells ...
Immunology for Surgeons: The Basics 101
Immunology for Surgeons: The Basics 101

... IL-1: pro-inflammatory and wound healing; macrophages, neutrophils, fibroblasts, NK cells, endothelial cells, vascular smooth muscle; fever, vasodilation, hypotension, collagen deposition, T-and B-cell proliferation, IL-2 and IL-2R upregulation IL-2: “T-cell growth factor” in response to IL-1; NK ce ...
week six summary - fundamentals of immunology
week six summary - fundamentals of immunology

... TYPES OF IMMUNE RESPONSES TO TUMOR-SPECIFIC ANTIGENS • May involve B cell and CD4 T cell responses • Antibodies and complement bind to antigens on the surface of cancer cells and kill them • CD8 T cells may recognize tumor antigen peptides on MHCI molecules and kill targets • Macrophages and Natu ...
Slide 1
Slide 1

... • Class I molecules “present” peptides from molecules that are made inside the cell (endogenous processing pathway). Viral particles, for example, are made internally. • Together the peptide and MHC form a shape (3-D structure) that may match (complement) the surface of a T cell receptor • MHC Class ...
I. Immunity
I. Immunity

... blood cells and antibodies 1. White blood cells: two types-T cells and B cells 2. Antibody—protein that disables antigens 3. B cells—makes antibodies 4. T cells—helps make antibodies, kills infected cells 5. Memory B cells—used if attacked again by same antigen -Draw Fig 39.12 p 1037 ...
1-overview
1-overview

... How do immune cells communicate? Extensive cell-cell contact Membrane protein interaction Immune synapse ...
Assessment of immune function.Management of patients with im
Assessment of immune function.Management of patients with im

... • Agent of primary immune response ...
Fighting Infectious Disease
Fighting Infectious Disease

Severe combined immune deficiency syndrome
Severe combined immune deficiency syndrome

... “Bubbly boy disease” Known and discovered in 1970’s and 80’s David Vetter X – linked syndrome Wore a plastic germ free bubble for 12 years Born without a working immune system Gene mutation Bubble = protect from outside environment David Vetter’s brother had same disease Bone Marrow Transplant = Vic ...
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File

... The additional blood supply makes the injured area red and inflamed, and it swells up due to the stretched capillary walls becoming more permeable which causes them to leak fluid into neighbouring tissues ...
Immunity - Misericordia University
Immunity - Misericordia University

... • Individual targets are selected for attack by the lymphocytes that can bind that target (antigen) • Antigens (Ag) – any large substance not normally found in the body; these illicit an immune response (immunogenic and immuno-reactive) • Haptens are small molecules that can trigger an immune respon ...
Belikov
Belikov

... MPhs acquire repertoires of active enhancers that are instructed by the microenvironmental signals specific to given tissue… … which affects the regulatory landscape of a cell via the induction of specific trx factors, leading to the expression of genes involved in the unique functional pathways of ...
Distinguished Visitor Programme
Distinguished Visitor Programme

... 13 Nov 2002 (Wed), 6.15-7.15 pm, Clinical Research Centre (CRC) Auditorium, Faculty of Medicine, MD 11, National University of Singapore, 10 Medical Drive, Singapore 117597 "Order from Disorder Sprung: Recognition and Regulation in the Immune System" "Milton's epic poem "Paradise Lost" supplies a co ...
Preventing Communicable Diseases
Preventing Communicable Diseases

... Some “B” and “T” cells actually have a memory and circulate through the body looking for “bad” invaders who have been there before- if found, they begin the attack to prevent illnesses. Active immunity- developed by your body Artificial immunity- vaccine- a preparation of dead or weakened pathogens ...
B cells and T cells Immunoglobulins
B cells and T cells Immunoglobulins

... - many different types of cells mediate the immune response to destroy bacteria and viruses as well as pre-cancerous cells ...
Slide 1 - AccessMedicine
Slide 1 - AccessMedicine

B cell
B cell

... to destroy antigen. Antibodies are divided into five major classes, IgM, IgG, Iga, IgD and IgE, based on their constant region structure and immune function. ...
Title - Iowa State University
Title - Iowa State University

... b.) Increase size of the lamella c.) Change flow of blood and water opposite to parallel d.) Decrease operculum flap size e.) None of the above 3. Which of the following is NOT true of hemoglobin? a.) A protein with four subunits b.) Binds CO2 c.) Binds O2 d.) Binds H+ e.) All of the above are true ...
Immune System Period 1 - Mercer Island School District
Immune System Period 1 - Mercer Island School District

... The main function(s) of the body system The main organs (or cell types) of this system and the function of each part At least one example of how this system helps to maintain homeostasis in the body Explanation of how the system works with other systems (some specified below) A description of at lea ...
Immune System and Transpiration Practice Qui
Immune System and Transpiration Practice Qui

... B. To bring white blood cells to the site of infection C. To deprive invading pathogens of oxygen needed for them to undergo cellular respiration D. To active T cells to release antibodies 2. Which of the following best describes the role of phagocytes such as neutrophils and macrophages in the immu ...
40 -2 THE IMMUNE SYSTEM
40 -2 THE IMMUNE SYSTEM

... Specific Defense 3. Immune Response – A series of specific defenses designed to attack a particular pathogen. Antigen – A foreign protein ID) that triggers an immune response. Lymphocytes – WBCs in body that recognize and destroy antigens. B Cells & T Cells are produced in bone marrow. B cells matur ...
File
File

... a. Primary immune response by an organism because the pathogen is typically being recognized as many antigens & not just one b. For example, a virus is typically made up of several different kinds of proteins & each protein type can cause an immune response c. Thus several different kinds of B cells ...
File - Biology with Radjewski
File - Biology with Radjewski

...  Insulin is an effector signal in that when it binds to receptors on target cells, it changes the activity of these effectors in that they increase their rate of glucose absorption. – This reduces the glucose level in the blood, removing the stimulus that caused insulin secretion by the ...
Supplementary Figure Legends (doc 28K)
Supplementary Figure Legends (doc 28K)

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Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
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