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Thymus
Thymus

... The site that lymphocytes generate and mature into functional cells Bone marrow or Bursa, and Thymus , Thymus , Peripheral immune organs or secondary lymphoid organs and tissues The sites that T and B lymphocytes reside in and respond to antigens spleen , lymph nodes , mucosal immune system ...
LEARNING OBJECTIVES Genesis and General Characteristics of
LEARNING OBJECTIVES Genesis and General Characteristics of

... Are similar structurally, but are functionally distinct and unrelated cell types ...
Lymphatic Lecture Notes Page
Lymphatic Lecture Notes Page

... Mucosa-associated lymphatic tissue (M.A.L.T.) Nodules in mucosa of G.I., urinary, reproductive tracts & respiratory airways - Tonsils in pharynx (protect against inhaled/ingested foreign substances) - Peyer’s patches (Lymph nodules) in small intestine ...
Adaptive immunity
Adaptive immunity

... activate phagocytes to destroy microbes that have been ingested by the phagocytes into phagocytic vesicles. Other T lymphocytes kill any type of host cells that are having infectious microbes in the cytoplasm. The antibodies produced by B lymphocytes are designed to specifically recognize extracellu ...
Document
Document

... IL-1β: another pro-inflammatory cytokine that Figure 1: Data from Opticon Monitor 2, displaying the RT-qPCR results of IL-10 expressed in spleen samples of 24 broilers ...
Lecture 2: Immunology of Fish and Shrimp
Lecture 2: Immunology of Fish and Shrimp

... Differentiates between “self” and “non-self” Works with several types of white blood cells, located throughout the body, that work together in a highly integrated way ...
(active) Immunity B cell AP Biology
(active) Immunity B cell AP Biology

... You need trained assassins to recognize & kill off these infected cells! ...
Dealing with Garbage is the Immune System`s Main Job
Dealing with Garbage is the Immune System`s Main Job

... promotes antibody production by B cells to facilitate trash clearance. Dendritic cells at the site pick up garbage that contains PAMPS or DAMPS. They respond to the stimulus, spread a local cytokine alarm, mature, and then run to the lymph node to direct T cells to act. During their maturation and t ...
Document
Document

... Phagocytosis is a specific form of endocytosis by which cells internalise solid matter, including microbial pathogens. While most cells are capable of phagocytosis, it is the professional phagocytes of the immune system, including macrophages, neutrophils and immature dendritic cells, that truly exc ...
Synthetic Nanovaccines
Synthetic Nanovaccines

... the University of Alabama-Birmingham and at UNMC tozhe immune deficits seen in mice also are present in humans with Parkinson’s disease. The cause of Parkinson’s disease — which affects more than 4 million people worldwide — is the loss of neurons that produce dopamine, a nerve signaling chemical th ...
The body`s response to infection File
The body`s response to infection File

... https://www.youtube.com/watch?v=CkTKZTCxrtc ...
Lac 2
Lac 2

... When the immune system encounters foreign cells or tissue, it responds strongly to rid the host of the invaders.However, in some cases, the transplantation of cells or an organ from another individual, although viewed by the immune system as a foreign invasion, may be the only possible treatment for ...
Non-Specific Defenses
Non-Specific Defenses

... Some bacteria evade ...
05070302
05070302

... growth factor (NGF) receptor ,which is expressed in many kinds of cells′surface. ...
Introduction to Microbial Pathogenesis
Introduction to Microbial Pathogenesis

... eosinophilic or basophilic inclusion bodies ...
the immune system - Regenerative Medicine Partnership in Education
the immune system - Regenerative Medicine Partnership in Education

... that literally eat germs covered by antibodies. 4. Neutrophils (new’-tro-fills) are the white blood cells that are the “first responders” to infections. We have more neutrophils than any other type of white blood cell. Their job is to patrol the body looking for germs. When they find an infection, t ...
IMMUNITY AND IMMUNIZATION
IMMUNITY AND IMMUNIZATION

... • Specific component against each new disease encountered is when exposure to a specific pathogen. • non-specific components act either as barriers or as eliminators of wide range of pathogens irrespective of antigenic specificity ...
Nonspecific and Specific Immunity
Nonspecific and Specific Immunity

Pset 6 Solutions
Pset 6 Solutions

... Circle the cells types that produce and secrete IgG (choose from mature B cells, memory B cells, Plasma cells). ...
Notes on Acquired Immunity
Notes on Acquired Immunity

... Cytotoxic proteins store in granules a polarized fashion o Perforin: aids in delivering contents of granules into target cell o Granzymes: serine proteases; activate apoptosis in target cell o Granulysin: antimicrobial actions; can induce apoptosis Lysis primarily mediated by perforin (holes in targ ...
CD8 - Molecular and Cell Biology
CD8 - Molecular and Cell Biology

... regions of MHC I (CD8) or II (CD4) ...
Kellogg Honors College Capstone Poster
Kellogg Honors College Capstone Poster

... Chemotherapy is a treatment in which cytotoxic drugs aim to cease the regeneration of cancer cells. Chemotherapy drugs are engineered to weaken tumor cells and as a result the body’s immune system has a better chance of eliminating the deadly cancer cells. Although chemotherapy may be practiced on i ...
Immunologic Targeting - How to Channel a Minimal Response
Immunologic Targeting - How to Channel a Minimal Response

... 1) chemical mimes of known cell surface molecules were shown to be immunogenic, ie Globo H - first time that a synethetic molecule could break immunologic tolerance in man 2) role of carriers such as KLH and adjuvants such as QS21 in enhancing immunogenicity and facilitating the immune response. QS2 ...
Blood Cells Flashcards
Blood Cells Flashcards

... 9. What WBC secretes histamines? 10. What is it called when it leaves the circulation to enter the tissues? 11. Which WBC fights allergies and parasitic infections, and during these conditions, their numbers increase. 12. What are MONOCYTES called when they leave the circulation and enter the tissue ...
The Body`s Defenses
The Body`s Defenses

... Directions: Read the passage below. Answer the questions that follow. When the body is invaded, four important nonspecific defenses take action: the inflammatory response; the temperature response; proteins that kill or inhibit pathogens; and white blood cells, which attack and kill pathogens. Infla ...
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Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
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