Irreversible cell injury
... To eliminate cells that are no longer needed OR to maintain a steady number of various cell populations in tissues. ...
... To eliminate cells that are no longer needed OR to maintain a steady number of various cell populations in tissues. ...
T cells
... - TGF-β1 is the founding and predominant member of this family - controls proliferation, differentiation, and other functions in many cell types - acts as a negative autocrine growth factor - specific receptors for TGF-β activation trigger apoptosis when activated ...
... - TGF-β1 is the founding and predominant member of this family - controls proliferation, differentiation, and other functions in many cell types - acts as a negative autocrine growth factor - specific receptors for TGF-β activation trigger apoptosis when activated ...
Special fatty molecules pave novel way to treat infections
... that the fatty molecules produced in the thymus which were able to stimulate iNKT cells all have the chemical linkage called ether bonds. To validate the stimulatory activity of these special class of self-generated fatty molecules, the scientists artificially manufactured ether-bonded fatty molecul ...
... that the fatty molecules produced in the thymus which were able to stimulate iNKT cells all have the chemical linkage called ether bonds. To validate the stimulatory activity of these special class of self-generated fatty molecules, the scientists artificially manufactured ether-bonded fatty molecul ...
幻灯片 1
... 1. Self-antigen alteration/associated antigen 3） Cross antigen effect: A β Hemolytic streptococcus vs. human cardiac muscle Ag ...
... 1. Self-antigen alteration/associated antigen 3） Cross antigen effect: A β Hemolytic streptococcus vs. human cardiac muscle Ag ...
ADAPTIVE IMMUNITY
... viruses), fungi, malignant cells, and grafts of foreign tissue. After recognition of the foreign antigen by macrophages and helper T cells, these activated T cells, which are antigen specific, divide many times to form memory T cells and Cytotoxic (killer) T cells ...
... viruses), fungi, malignant cells, and grafts of foreign tissue. After recognition of the foreign antigen by macrophages and helper T cells, these activated T cells, which are antigen specific, divide many times to form memory T cells and Cytotoxic (killer) T cells ...
Word version
... 1. Active immunity Active immunity occurs when the animal produces antibodies either in response to natural challenges from disease, or as a result of vaccination. Once an animal has produced a specific antibody, it can produce more antibodies of the same type rapidly in response to an infection. Th ...
... 1. Active immunity Active immunity occurs when the animal produces antibodies either in response to natural challenges from disease, or as a result of vaccination. Once an animal has produced a specific antibody, it can produce more antibodies of the same type rapidly in response to an infection. Th ...
Student factsheet for this topic
... 1. Active immunity Active immunity occurs when the animal produces antibodies either in response to natural challenges from disease, or as a result of vaccination. Once an animal has produced a specific antibody, it can produce more antibodies of the same type rapidly in response to an infection. Th ...
... 1. Active immunity Active immunity occurs when the animal produces antibodies either in response to natural challenges from disease, or as a result of vaccination. Once an animal has produced a specific antibody, it can produce more antibodies of the same type rapidly in response to an infection. Th ...
ppt
... be detrimental or beneficial Numerous recent epidemiological studies show that certain vaccines are less effective in children that are infected with worms than those that have been cured using drugs (these are mostly vaccines that require a robust TH1 response) This is backed up by many studies in ...
... be detrimental or beneficial Numerous recent epidemiological studies show that certain vaccines are less effective in children that are infected with worms than those that have been cured using drugs (these are mostly vaccines that require a robust TH1 response) This is backed up by many studies in ...
26.1 Organs, Tissues, and Cells of the Immune System (cont.)
... • Rejection occurs when cytotoxic T cells and antibodies respond to the transplanted tissues as if they were pathogens. • Tissue rejection can be minimized in two ways. – Transplanting tissues with similar surface antigens to the recipient. – Administering immunosuppressing drugs. ...
... • Rejection occurs when cytotoxic T cells and antibodies respond to the transplanted tissues as if they were pathogens. • Tissue rejection can be minimized in two ways. – Transplanting tissues with similar surface antigens to the recipient. – Administering immunosuppressing drugs. ...
T-cell
... In contrast, B-cell development occurs in the bone marrow and is closely dependent upon interaction between a surface glycoprotein on nonlymphoid stromal cells called stem-cell factor (SCF) and its receptor on Bcell precursors ,kit tyrosine kinase. The thymus and the bone marrow are primary lymphoid ...
... In contrast, B-cell development occurs in the bone marrow and is closely dependent upon interaction between a surface glycoprotein on nonlymphoid stromal cells called stem-cell factor (SCF) and its receptor on Bcell precursors ,kit tyrosine kinase. The thymus and the bone marrow are primary lymphoid ...
NK cells - University of Pittsburgh School of Medicine
... Toll-like receptor (TLR) signaling pathway. TLRs recognize specific patterns of microbial components. MyD88 is an essential adaptor for all TLRs and is critical to the inflammatory response. Lipopolysaccharide (LPS)-induced activation of signaling molecules such as IRF-3, PKR, MAP kinase, and NF-kB ...
... Toll-like receptor (TLR) signaling pathway. TLRs recognize specific patterns of microbial components. MyD88 is an essential adaptor for all TLRs and is critical to the inflammatory response. Lipopolysaccharide (LPS)-induced activation of signaling molecules such as IRF-3, PKR, MAP kinase, and NF-kB ...
Computer Simulation for the Development of Immune Cells
... T8 cells, the killer cells, kill the bad or infected cells ...
... T8 cells, the killer cells, kill the bad or infected cells ...
Innate immune recognition
... Discussion sections start next week. The journal article Akira et al, and the first problem set will be covered. Both are available on the website. Office Hours: Questions about the lecture material are best addressed ...
... Discussion sections start next week. The journal article Akira et al, and the first problem set will be covered. Both are available on the website. Office Hours: Questions about the lecture material are best addressed ...
Lab Dx Day 1 Intro to Hematopoietic System
... Immune proteins are the most diverse proteins known. Immune system required to survive infection Antibodies-aka ___________ vast number of antibodies made by re-shuffling a small set of gene fragments ...
... Immune proteins are the most diverse proteins known. Immune system required to survive infection Antibodies-aka ___________ vast number of antibodies made by re-shuffling a small set of gene fragments ...
Central Nervous System Control of The Immune System
... While developing in the thymus gland, any T cell that reacts to the thymus's major histocompatibility complex (MHC) is eliminated. It is estimated that anywhere from 95-99% of all T cells are eliminated during this process. T cells that tolerate the MHC are allowed to mature and leave the thymus whe ...
... While developing in the thymus gland, any T cell that reacts to the thymus's major histocompatibility complex (MHC) is eliminated. It is estimated that anywhere from 95-99% of all T cells are eliminated during this process. T cells that tolerate the MHC are allowed to mature and leave the thymus whe ...
APSpring14_142Q2Aans..
... Active artificially acquired immunity Passive artificially acquired immunity A&C ...
... Active artificially acquired immunity Passive artificially acquired immunity A&C ...
4-Microbiota Part
... worldwide. Although their etiology is complex, both result from interplay between behavior, environment and genetic factors. Within ambient determinants, human overall gut bacteria have been identified as a crucial mediator of obesity and its consequences. Gut microbiota plays a crucial role in gast ...
... worldwide. Although their etiology is complex, both result from interplay between behavior, environment and genetic factors. Within ambient determinants, human overall gut bacteria have been identified as a crucial mediator of obesity and its consequences. Gut microbiota plays a crucial role in gast ...
Sample Chapter PDF (Chapter 1 — 92K)
... The remaining postulates of the clonal selection theory account for this process of selection by the antigen from among all the available cells in the repertoire. 4. Immunocompetent lymphocytes combine with the foreign antigen, or a portion of it, termed epitope, by virtue of their surface receptors ...
... The remaining postulates of the clonal selection theory account for this process of selection by the antigen from among all the available cells in the repertoire. 4. Immunocompetent lymphocytes combine with the foreign antigen, or a portion of it, termed epitope, by virtue of their surface receptors ...
Monoclonal and Polyclonal Antibodies
... structural variation between the five classes of antibodies, or immunoglobulins. In the last forty years, scientists have been able to harness this knowledge to develop an array of biological assays that have since become essential in the modern molecular biology laboratory. Polyclonal antibodies bi ...
... structural variation between the five classes of antibodies, or immunoglobulins. In the last forty years, scientists have been able to harness this knowledge to develop an array of biological assays that have since become essential in the modern molecular biology laboratory. Polyclonal antibodies bi ...
Cytokines
... 2. It has since been found that interleukins are produced by a wide variety y of body y cells. The function of the immune system depends in a large part on interleukins, And rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majorit ...
... 2. It has since been found that interleukins are produced by a wide variety y of body y cells. The function of the immune system depends in a large part on interleukins, And rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majorit ...
Specific Defenses of the Host - Suffolk County Community College
... Communication chemicals = cytokines -chemical messengers used within immune system (proteins or glycoproteins) -many kinds, each has specific message Cells = T cells -originate from stem cells in bone marrow but mature in thymus, travel to blood & lymph -each only recognizes one antigen -when it bin ...
... Communication chemicals = cytokines -chemical messengers used within immune system (proteins or glycoproteins) -many kinds, each has specific message Cells = T cells -originate from stem cells in bone marrow but mature in thymus, travel to blood & lymph -each only recognizes one antigen -when it bin ...
Type of immune response
... T cells: T helper - produce stimulatory and regulatory cytokines T cells: T cytotoxic/suppressor – contact-dependent cytotoxicity, regulation of immune response NK cells: direct killing of cells (innate arm of IS) Bob Luebke ITB/ETD/NHEERL ...
... T cells: T helper - produce stimulatory and regulatory cytokines T cells: T cytotoxic/suppressor – contact-dependent cytotoxicity, regulation of immune response NK cells: direct killing of cells (innate arm of IS) Bob Luebke ITB/ETD/NHEERL ...
Immunity and the Invertebrates
... an army. Moving through the blood and lymph glands, lymphocytes are normally at rest, but they become active and multiply if they encounter specific molecules called antigens that are associated with foreign organisms. Lymphocytes are of two classes—B and T. B lymphocytes secrete antibodies—defensiv ...
... an army. Moving through the blood and lymph glands, lymphocytes are normally at rest, but they become active and multiply if they encounter specific molecules called antigens that are associated with foreign organisms. Lymphocytes are of two classes—B and T. B lymphocytes secrete antibodies—defensiv ...
File
... the ingestion of any solid matter ( including microorganisms) by a cell Phagocytes: white blood cells or derivatives of white blood cells A. Formed elements of the Blood – cells or cell fragments 1. plasma – fluid portion of the blood 2. erythrocytes – red blood cells 3. leukocytes – white blood cel ...
... the ingestion of any solid matter ( including microorganisms) by a cell Phagocytes: white blood cells or derivatives of white blood cells A. Formed elements of the Blood – cells or cell fragments 1. plasma – fluid portion of the blood 2. erythrocytes – red blood cells 3. leukocytes – white blood cel ...