Claire Baldock
... NGF, named TrkA and act as antagonist for the binding of NGF to TrkA, and which prevents the functional activation of TrkA by NGF, in the manufacture of a pharmacological composition for treatment of neurological pathologies comprised within the following group: chronic pain and acute pain.” ...
... NGF, named TrkA and act as antagonist for the binding of NGF to TrkA, and which prevents the functional activation of TrkA by NGF, in the manufacture of a pharmacological composition for treatment of neurological pathologies comprised within the following group: chronic pain and acute pain.” ...
A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade
... Washing out macrophages from peritoneal cavity also reduced F4/80hi macrophages in injury (Figures 2F and S2C). In addition, peritoneal cells from LysM-eGFP mice (Faust et al., 2000), in which >85% of the GFP+ population are GATA6+ macrophages, were adoptively transferred into the peritoneum of a no ...
... Washing out macrophages from peritoneal cavity also reduced F4/80hi macrophages in injury (Figures 2F and S2C). In addition, peritoneal cells from LysM-eGFP mice (Faust et al., 2000), in which >85% of the GFP+ population are GATA6+ macrophages, were adoptively transferred into the peritoneum of a no ...
Macaques infected with attenuated simian immunodeficiency virus
... carrying multiple deletions, which are therefore unlikely to revert (Wyand et al., 1996), may induce disease in neonatal macaques (Baba et al., 1995). Nevertheless, investigation of the mechanisms of superinfection resistance may reveal insights into lentivirus infection and immunity that may be exp ...
... carrying multiple deletions, which are therefore unlikely to revert (Wyand et al., 1996), may induce disease in neonatal macaques (Baba et al., 1995). Nevertheless, investigation of the mechanisms of superinfection resistance may reveal insights into lentivirus infection and immunity that may be exp ...
The Effect of Selenium Supplementation in Sheep with Foot
... Neutrophil Marker mRNAs •L-selectin-- cell surface glycoprotein involved in binding and rolling of leukocytes along endothelial walls facilitating migration to site of inflammation. •IL-8 Receptor-- receptor that controls the interaction of neutrophils with the epithelial cell barrier. •MPO (myelop ...
... Neutrophil Marker mRNAs •L-selectin-- cell surface glycoprotein involved in binding and rolling of leukocytes along endothelial walls facilitating migration to site of inflammation. •IL-8 Receptor-- receptor that controls the interaction of neutrophils with the epithelial cell barrier. •MPO (myelop ...
Ginkgo biloba extract EGb 761 has anti
... III consists of an automated bright-field microscope with image and proprietary processing analysis software for evaluating tissue sections on glass microscope slides. For each slide, the entire tissue section was scanned, and results are represented as the percentage of cells staining positive. Exa ...
... III consists of an automated bright-field microscope with image and proprietary processing analysis software for evaluating tissue sections on glass microscope slides. For each slide, the entire tissue section was scanned, and results are represented as the percentage of cells staining positive. Exa ...
Regulatory T Cells: Mechanisms of Differentiation and Function
... engagement of TCRs by self antigens induces anergy. Peripheral tolerance is also reinforced by the requirement of simultaneous engagement of TCRs by a cognate peptide-MHC complex and the T cell costimulatory receptor CD28 by CD80 and CD86 (2). CD80 and CD86 are induced on antigen-presenting cells (A ...
... engagement of TCRs by self antigens induces anergy. Peripheral tolerance is also reinforced by the requirement of simultaneous engagement of TCRs by a cognate peptide-MHC complex and the T cell costimulatory receptor CD28 by CD80 and CD86 (2). CD80 and CD86 are induced on antigen-presenting cells (A ...
here - Wound Infection Institute
... following an infection (usually caused by bacteria, particularly staphylococci or bacteroides, or parasites) or foreign materials (e.g. splinters, bullet wounds, or injecting needles). It is a defensive and localising reaction of the tissue to prevent the spread of infectious materials to other part ...
... following an infection (usually caused by bacteria, particularly staphylococci or bacteroides, or parasites) or foreign materials (e.g. splinters, bullet wounds, or injecting needles). It is a defensive and localising reaction of the tissue to prevent the spread of infectious materials to other part ...
A human SARS-CoV neutralizing antibody against epitope on S2
... An immune antibody phage-display library was constructed from B cells of SARS convalescent patients. More than 80 clones were selected from the library by using the whole inactivated SARS-CoV virions as target. One human scFv, B1, was characterized extensively. The B1 recognized SARS pseudovirus in ...
... An immune antibody phage-display library was constructed from B cells of SARS convalescent patients. More than 80 clones were selected from the library by using the whole inactivated SARS-CoV virions as target. One human scFv, B1, was characterized extensively. The B1 recognized SARS pseudovirus in ...
dendritic cell-specific ICAM- grabbing non-integrin
... C-type lectins are calcium-dependent carbohydrate-binding proteins with a wide range of biological functions, many of which are related to immunity. DC-SIGN (dendritic cell-specific ICAM-grabbing non-integrin, where ICAM is intercellular adhesion molecule) is a recently described mannose-specific C- ...
... C-type lectins are calcium-dependent carbohydrate-binding proteins with a wide range of biological functions, many of which are related to immunity. DC-SIGN (dendritic cell-specific ICAM-grabbing non-integrin, where ICAM is intercellular adhesion molecule) is a recently described mannose-specific C- ...
Tissue Microenvironments Define and Get Reinforced by
... factor (GM-CSF) [1]. This bactericidal macrophage phenotype appears in early phases of tissue injury shortly after the recruitment of neutrophils to enforce local host defense against pathogens. In PAMP-rich environments proinflammatory macrophages are potentially life-saving which outweighs the ass ...
... factor (GM-CSF) [1]. This bactericidal macrophage phenotype appears in early phases of tissue injury shortly after the recruitment of neutrophils to enforce local host defense against pathogens. In PAMP-rich environments proinflammatory macrophages are potentially life-saving which outweighs the ass ...
Zebrafish Models for Human Acute Organophosphorus Poisoning Natàlia Garcia-Reyero
... 1. Development of chemical models of OPP, with different grades of severity, in zebrafish larvae by using chlorpyrifos-oxon as a prototypic OP compound 2. Characterization of the models, by analysing the adverse effects at different levels of organization (transcriptional, biochemical, ultrastructur ...
... 1. Development of chemical models of OPP, with different grades of severity, in zebrafish larvae by using chlorpyrifos-oxon as a prototypic OP compound 2. Characterization of the models, by analysing the adverse effects at different levels of organization (transcriptional, biochemical, ultrastructur ...
Immunohistochemical and ultrastructural localization of leptin and
... macrophages (Fig. 5E and F). Macrophages were characterized by typical primary and secondary lysosomes, a welldeveloped Golgi complex, small amounts of rough endoplasmic reticulum, elongated mitochondria, and microvilli. DISCUSSION ...
... macrophages (Fig. 5E and F). Macrophages were characterized by typical primary and secondary lysosomes, a welldeveloped Golgi complex, small amounts of rough endoplasmic reticulum, elongated mitochondria, and microvilli. DISCUSSION ...
Regulation of macrophage development and function in peripheral
... subsequent cell labelling. Thus, too little Cre expression can result in incomplete labelling of the target cell populations, whereas ‘leaky’ expression can result in undesired cells being labelled. Mass cytometry (also known as CyTOF). This approach combines mass spectrometry with the principles of ...
... subsequent cell labelling. Thus, too little Cre expression can result in incomplete labelling of the target cell populations, whereas ‘leaky’ expression can result in undesired cells being labelled. Mass cytometry (also known as CyTOF). This approach combines mass spectrometry with the principles of ...
Responses of Bovine Endometrial Epithelial Cells to Pathogens
... following characterisation of tissue samples used for culture. Examination of cell proliferation, survival and apoptosis after challenges with various doses of LPS revealed that cow and tissue characteristics did not influence proliferation of bovine endometrial epithelial cells (bEEC) in response t ...
... following characterisation of tissue samples used for culture. Examination of cell proliferation, survival and apoptosis after challenges with various doses of LPS revealed that cow and tissue characteristics did not influence proliferation of bovine endometrial epithelial cells (bEEC) in response t ...
- Wiley Online Library
... In the natural situation the host is often able to mount an effective immune response against protozoan parasites. However, a long-lasting effective immunity can only be maintained when the host remains a carrier. This is termed premunition [35]. It is either acquired as the result of a persistent l ...
... In the natural situation the host is often able to mount an effective immune response against protozoan parasites. However, a long-lasting effective immunity can only be maintained when the host remains a carrier. This is termed premunition [35]. It is either acquired as the result of a persistent l ...
Full-Text PDF
... differentiation and migration [42]. Recently, significant research progress has been made on chicken type I interferon (ChIFN). It was first identified as avian interferon using an RT-PCR approach [29]. The ChIFNα was amplified from chicken liver [43], while the ChIFNβ was first identified by southe ...
... differentiation and migration [42]. Recently, significant research progress has been made on chicken type I interferon (ChIFN). It was first identified as avian interferon using an RT-PCR approach [29]. The ChIFNα was amplified from chicken liver [43], while the ChIFNβ was first identified by southe ...
On the following pages you will find one of the... Applications and Summary Statements indexed here:
... circumvent in order to cause disease. Several components of this system are conserved in eukaryotes. Recently, bacterial pathogen effectors that are injected into host cells by type III protein secretion systems (TTSSs) have been shown to be capable of suppressing innate immunity in eukaryotes. The ...
... circumvent in order to cause disease. Several components of this system are conserved in eukaryotes. Recently, bacterial pathogen effectors that are injected into host cells by type III protein secretion systems (TTSSs) have been shown to be capable of suppressing innate immunity in eukaryotes. The ...
Antiphospholipid Antibodies: Their Origin and Development
... Natural antibodies appear without prior infection or immunization. The majority is of the immunoglobulin (Ig) M isotype, but IgG or IgA have also been observed [13,14]. They are secreted mainly by B1 cells, a specific subset of B-lymphocytes. Activation of B1 cells does not depend on antigenic chall ...
... Natural antibodies appear without prior infection or immunization. The majority is of the immunoglobulin (Ig) M isotype, but IgG or IgA have also been observed [13,14]. They are secreted mainly by B1 cells, a specific subset of B-lymphocytes. Activation of B1 cells does not depend on antigenic chall ...
dendritic cell-based tumor vaccination for high
... Group Biomedical Sciences Faculty of Medicine Laboratory of Experimental Immunology Department of Neurosurgery ...
... Group Biomedical Sciences Faculty of Medicine Laboratory of Experimental Immunology Department of Neurosurgery ...
Reprint - Institute of Biochemistry - Goethe
... secretion of cytokines, which mediate both humoral (antibody dependent) and cell-mediated immunity. MHC I molecules, on the other hand, present peptides from viruses, intracellularly replicating bacteria, or from tumor-specific proteins. CD8+ T lymphocytes recognize the complex of MHC I molecules an ...
... secretion of cytokines, which mediate both humoral (antibody dependent) and cell-mediated immunity. MHC I molecules, on the other hand, present peptides from viruses, intracellularly replicating bacteria, or from tumor-specific proteins. CD8+ T lymphocytes recognize the complex of MHC I molecules an ...
Genetic analysis of innate immunity in resistance to
... varies with the strain of mouse used. They can show little evidence of an inflammatory reaction, contain large infiltrates of polymorphs and/or macrophages, or form granulomas. A similar pattern of tissue damage has been observed in other affected organs, although the extent and number of lesions te ...
... varies with the strain of mouse used. They can show little evidence of an inflammatory reaction, contain large infiltrates of polymorphs and/or macrophages, or form granulomas. A similar pattern of tissue damage has been observed in other affected organs, although the extent and number of lesions te ...
PhD Rika 140511 - Laboratory of Parasitology
... one study in Peru, the presence of Giardia cysts in stool samples could not be correlated with symptoms at all (Hollm-Degado et al., 2008). It is suggested that the ...
... one study in Peru, the presence of Giardia cysts in stool samples could not be correlated with symptoms at all (Hollm-Degado et al., 2008). It is suggested that the ...