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FUNCTIONS OF THE BLOOD
FUNCTIONS OF THE BLOOD

... • Binding to receptors- polysaccharides or similar bacterial cell wall substances [nonspecific]. • Electrical charge of the surface- positive charge in living tissue. No charge in dead tissues and negative out side of bacteria. • Opsonized material is said to be “tasty” to phagocytes. June 2013 ...
10th practice 2012
10th practice 2012

... of staining which is more characteristic of the presence of autoantibodies to extractable nuclear antigens, particularly ribonucleoprotein. This pattern is not very specific, but may be seen with an entity called "mixed connective tissue disease" which is a mix between SLE, scleroderma, and polymyos ...
Immunology Ch 1 1-22 [4-20
Immunology Ch 1 1-22 [4-20

... -All lymphocytes arise in bone marrow; B cells mature in marrow, T cells mature in thymus -sites where mature lymphocytes are produced are called generative lymphoid organs, mature lymphocytes enter circulation and enter peripheral lymphoid organs, where they meet antigen -Naïve lymphocytes recogniz ...
Cell-Mediated Immunity Thought Questions Basic Science Review
Cell-Mediated Immunity Thought Questions Basic Science Review

MCB3020 Final Review Practice Part 2
MCB3020 Final Review Practice Part 2

... 19. Which of the following is a difference between a bacterial virus and an animal virus?  a. Bacterial viruses have RNA and animal viruses have DNA  b. Animal viruses have a protein coat and bacterial viruses do not  c. The nucleic acids and protein coat of an animal virus enter the host, but only  ...
10. practice 2011
10. practice 2011

... of staining which is more characteristic of the presence of autoantibodies to extractable nuclear antigens, particularly ribonucleoprotein. This pattern is not very specific, but may be seen with an entity called "mixed connective tissue disease" which is a mix between SLE, scleroderma, and polymyos ...
Effector T Cells and Cytokines - jsi-men
Effector T Cells and Cytokines - jsi-men

Power Point
Power Point

... • A group of proteins present in the plasma of all individuals. Part of the innate immune system. • A major biological effector system of both the innate and the adaptive immune responses. • The C components are present in the plasma in an inactive state. • Upon activation most C components become p ...
Type III Hypersensitivity
Type III Hypersensitivity

... although IgM may also be involved. This form of hypersensitivity has a lot in common with type I except that the antibody involved is IgG and therefore not prebound to mast cells, so that only preformed complexes can bind to the low affinity Fcgamma RIII. The antigen is soluble and not attached to t ...
Neutrophil Derived Microvesicles: Emerging Role
Neutrophil Derived Microvesicles: Emerging Role

... Microvesicle Stimulation and Mechanisms of formation  Similar to other global microvesicle populations, neutrophil derived microvesicles can be elicited from both apoptotic and activated cells by a large number of stimuli. Microparticle composition appears to be different based on stimuli used for ...
Ch 43-45 PPT
Ch 43-45 PPT

... killer T cells - attacks foreign cells, causes them to lyse ...
B cells take their time: sequential IgG class switching over
B cells take their time: sequential IgG class switching over

... responses and the formation of diverse antigen-experienced B-cell subsets in humans. Furthermore, the diversity of antigens, anatomical locations of immune responses and the diversity of antigen-experienced human B-cell subsets can blur the effects of temporal CSR. To overcome these limitations, it ...
Simulating immunity
Simulating immunity

... 2. How are macrophages different from T-cells and B-cells in the types of antigens to which they react? 3. What does the candy passed to the various cells represent? 4. What did the handcuffs represent? 5. How did the T-helper cells know that the body had been invaded? 6. What did the squirt guns re ...
Matthias Noll Institut für Molekulare Parasitologie Humboldt
Matthias Noll Institut für Molekulare Parasitologie Humboldt

... abundant eukaryotic pathogens of warm-blooded animals, including humans. Successful infection, pathogenesis and transmission of the parasite depend on multiplication, persistence and interconversion of its two asexual stages. The fast-replicating tachyzoites cause acute tissue necrosis and then diff ...
LECTURE 8 Immunopathologic processes Theme 11. Immune
LECTURE 8 Immunopathologic processes Theme 11. Immune

... rarely – acute disease with prevailing injury of immunogenesis organs and blood cells, the final stage of which is complete oppression of immune system. Etiology – Acquired immune deficiency syndrome (AIDS) ...
Immunology: Animal Defense Systems
Immunology: Animal Defense Systems

... Concept 31.5 The Adaptive Cellular Immune Response Involves T Cells and Their Receptors ...
574. SynergisticalSynergistically Transcutaneous Immunotherapy
574. SynergisticalSynergistically Transcutaneous Immunotherapy

... Statement of Purpose: Despite the promising efficacy of immunoregulation in cancer therapy, the clinical benefit has been restricted by inefficient infiltration of lymphocytes in the evolution of immune evasion. Also, the immune-related adverse events have often occurred due to the off-target bindin ...
Folie 1
Folie 1

... of PTC including a humanized mouse model in this patient. Results: CD4 count is stable between 800-1000 cells/µl, the homozygous CCR5 promoter variant A59029G but no delta 32 deletion was detected, HLA-I subtype was A 01, 02 B: 44, 52; no viral RNA or DNA was detected using ultrasensitive techniques ...
MicroRNAs of the immune system - Laboratory of Lymphocyte Biology
MicroRNAs of the immune system - Laboratory of Lymphocyte Biology

... miRNAs in hematopoietic cells, many of which are expressed specifically in cells and tissues of immune relevance. In fact, cells of the hematopoietic system can be selectively identified from other tissues by their miRNA expression profile; they all express five highly specific miRNAs: miR-142, miR- ...
ImmunLec22
ImmunLec22

... • Took Sing Sing prisoners (male) and injected them with different blood types. • Identified a D antigen, a minor antigen that is T cell dependent and evokes a Ig G response, but only if Ig M to major blood group antigens hasn’t occurred. • Developed Rhogam , recombinant Ig G to D antigen. Injected ...
Lily Dara, MD Instructor in Clinical Medicine University of Southern
Lily Dara, MD Instructor in Clinical Medicine University of Southern

... In the past decade our understanding of idiosyncratic drug induced liver injury (IDILI) and the contribution of genetic susceptibility and the adaptive immune system to the pathogenesis of this disease process has grown tremendously. One of the characteristics of IDILI is that it occurs rarely and o ...
immuno chapter 4 [5-12
immuno chapter 4 [5-12

... Antigen Recognition in Adaptive Immune System  Recognition of antigen is initiating event in lymphocyte responses; specific antigen recognition is task of membrane-bound antibodies on B cells and TCRs on T lymphocytes  Principal function of cellular receptors in immune system is to detect external ...
Lecture 3: Introduction of immune system II - BIDD
Lecture 3: Introduction of immune system II - BIDD

... • Activation of T and B cells are different: – T cells: specific recognition of peptide/MHC complex (signal 1) and costimulatory signals by APC (Signal 2) – B cells: recognize native proteins (signal 1). May/may not require signal 2 from CD4+ Th cells (TD and TI antigens) ...
Lymphatic Study Guide - Belle Vernon Area School District
Lymphatic Study Guide - Belle Vernon Area School District

... ❛❛Adaptive immunity involves the ability to recognize, respond to, and remember a particular❜❜ substance. A. Match these terms with the correct statement or definition: Allergic reaction, Foreign antigens, Antigens, Self antigens, _________________________1. General term for substances that stimulat ...
Viral Infection and immunity
Viral Infection and immunity

... T cells recognizes viral peptides presented by MHC molecules on cell surfaces Antigenic viral peptides can come from any viral protein TH1 CD4 responses are more important than TH2 responses CD8 cytotoxic T cells respond to viral peptide-class I MHC protein complexes on the cell surface TH2 CD4 resp ...
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Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
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