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Skin As An Immune Organ
Skin As An Immune Organ

Lecture 22
Lecture 22

... • Adaptive immunity develops as the need arises. • Two types: ...
Cytokines
Cytokines

... activating cells in a nonspecific fashion during an adaptive immune response ? 1. Cytokine receptors are often expressed on a cell only after that cell has interacted with antigen. In this way, cytokine activation is limited to Ag-activated lymphocytes. 2. Cytokines secreted at the junction of these ...
Course of Immunology
Course of Immunology

... - each thesis will be presented verbally afterwards on 13.11 and 20.11.2013 ...
Immune Responses
Immune Responses

... G) Fever 1) caused by pyrogens a) any chemical that causes an increase in body temperature b) most often released from WBC, as well as some bacteria 2) promote sequestration of iron & zinc 3) may aid interferon, inhibit microbe growth, & speed reaction time of defense cells ...
Healthy Trac™ Market For Digestive Health
Healthy Trac™ Market For Digestive Health

... Has Been Shown To Enhance Natural Killer Cell (NK) Activity. This Is Very Beneficial During The Ageing Process. Healthy Trac™ Naturally Stimulates The Immune System By Increasing Most Immune Cell Populations Including Monocytes And Dendritic Cells. ...
Drugs to Treat Autoimmune Diseases
Drugs to Treat Autoimmune Diseases

... • Immunosuppressive effects due to inhibition of enzyme involved in the metabolism of folic acid • Anti-inflammatory effects due to interruption of ...
Southern Methodist University
Southern Methodist University

Immunity
Immunity

Janeway`s Immunology
Janeway`s Immunology

... antigen X is more rapid and larger than the primary response (memory). Antibody levels decline with time after each immunization (contraction, the process that maintains homeostasis). The same features are seen in cell-mediated immune responses. ...
T-Cell Receptor Beta
T-Cell Receptor Beta

Chapter 40: Immune System Chapter 41: Nervous System Chapter
Chapter 40: Immune System Chapter 41: Nervous System Chapter

... longer fight off other infections because of the destruction of helper T cells.  If a person’s blood contains antibodies to HIV they are HIV positive.  HIV is transmitted through body fluids including blood. Can also be transmitted through sexual contact, breast milk, and ...
Hygiene hypothesis and allergic pathologies
Hygiene hypothesis and allergic pathologies

... weak, short term IL-4 ...
Anatomy - Immune system - UK College of Agriculture
Anatomy - Immune system - UK College of Agriculture

Presentation 3 Innate Immunity
Presentation 3 Innate Immunity

... • Describe the characteristics of the response • Understand recognition processes • Describe the cells involved and their effector functions ...
Cell permeable Foxp3 protein converts CD4 T cells to suppressor
Cell permeable Foxp3 protein converts CD4 T cells to suppressor

... CD4+CD25+ Tregs. Foxp3-transduced T cells have been studied for conversion of CD4+CD25- T cells to CD4+CD25+ Treg cells as well as for inhibition of T cell activation and proliferation. To study about Foxp3 function in T cells, we have generated a recombinant protein of Foxp3 combined with previousl ...
Course Objectives - Geisel School of Medicine
Course Objectives - Geisel School of Medicine

... Describe  T  and  B  cell  receptor  diversity  and  antigen  recognition Explain  the  role  of  tolerance,  when  and  how  it  occurs,  and  consequences  of  autoimmunity Compare  innate  and  adaptive  immune  responses Describe  how  pa ...
PFIZER’S CENTERS FOR THERAPEUTIC INNOVATION (CTI) CTI:
PFIZER’S CENTERS FOR THERAPEUTIC INNOVATION (CTI) CTI:

... CTI: an innovative Pfizer program that partners with leading academic medical centers and foundations nationwide to  accelerate the translation of novel targets to the clinic. CTI’s goal is to identify new compounds and accelerate research and  drug development from validated target to proof‐of‐mech ...
Course of Immunology
Course of Immunology

Transplants
Transplants

...  Use tissue from an "identical" (monozygotic) twin in the very rare cases that one is available. Being genetically identical, the recipient sees the transplant as "self", not as foreign, and does not mount an attack against it. The first successful kidney transplants (done in the mid 50s) were betw ...
Chapter 14: Resistance and the Immune System: Innate Immunity
Chapter 14: Resistance and the Immune System: Innate Immunity

... • Low to moderate fever supports the immune system by: • inhibiting rapid microbial growth • encouraging rapid tissue repair • heightening phagocytosis • Pyrogens are cytokines produced by: – some leukocytes – fragments from pathogens • They affect the hypothalamus, causing elevated body temperature ...
B cell
B cell

Inflammation in the Lung
Inflammation in the Lung

... ◦ Bacteria associated with most severe cases ◦ Flu can cause pneumonia ...
Why we need many “therapeutic targets”
Why we need many “therapeutic targets”

... Once T cells and other immune cells have become fully activated (which usually takes place while the cells are in one of the body’s lymph nodes), they use certain molecules on their surface to control their movement out of lymph nodes and into the blood stream. One of these molecules is called the “ ...
Diphtheria Toxin and Engineered Receptor
Diphtheria Toxin and Engineered Receptor

... Immunologists are using diphtheria toxin (DT) in studies to sort out the function of various immune cells. Diphtheria toxin is a potent inhibitor of protein synthesis and will kill about any cell to which it gains entry. Diphtheria toxin receptor (DTR), either simian or human, is genetically attache ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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