Immunology. Mucosal and Body Surface Defences Brochure
... The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces t ...
... The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces t ...
Types II and III: Antibody-Mediated and Antigen
... may affect the skin, joints, kidneys, brain, and other organs. Causes, incidence, and risk factors Systemic lupus erythematosus (SLE) is an autoimmune disease, which means the body's immune system mistakenly attacks healthy tissue. This leads to long-term (chronic) inflammation. The underlying cause ...
... may affect the skin, joints, kidneys, brain, and other organs. Causes, incidence, and risk factors Systemic lupus erythematosus (SLE) is an autoimmune disease, which means the body's immune system mistakenly attacks healthy tissue. This leads to long-term (chronic) inflammation. The underlying cause ...
Innate Immunity - microbiology and immunology on-line
... Antigen presentation for specific immune ...
... Antigen presentation for specific immune ...
The bright light produced at the CLS allows researchers to see the
... Merck scientists used the CLS’s crystallography facilities to fully determine the new cancer antibody’s structure, down to a 2.3 angstrom resolution. Understanding the three-dimensional structural details of a therapeutic antibody can help in understanding its physical properties and how it interact ...
... Merck scientists used the CLS’s crystallography facilities to fully determine the new cancer antibody’s structure, down to a 2.3 angstrom resolution. Understanding the three-dimensional structural details of a therapeutic antibody can help in understanding its physical properties and how it interact ...
Autoimmune diseases
... stimulatory hormone (TSH) This Ab is called as Long acting thyroid (LATS) stimulator or thyroid stimulating Ab (TSab). Primary causes: Stimulation of Thyroid gland to secrete more TH (Hyperthyroidism) resulting in Exophthalmus , bulging eyes & Goitre. In Graves’ disease, the antibodies do not de ...
... stimulatory hormone (TSH) This Ab is called as Long acting thyroid (LATS) stimulator or thyroid stimulating Ab (TSab). Primary causes: Stimulation of Thyroid gland to secrete more TH (Hyperthyroidism) resulting in Exophthalmus , bulging eyes & Goitre. In Graves’ disease, the antibodies do not de ...
Co-receptors
... characterised one is CD28, among others (ICOS, OX40, CD46…). Without receiving a second signal, the T cells remain mainly unresponsive, becoming anergic cells, or die. Cleverly, most of the ligands for these costimulatory molecules are induced by activation/maturation of the cells that present the p ...
... characterised one is CD28, among others (ICOS, OX40, CD46…). Without receiving a second signal, the T cells remain mainly unresponsive, becoming anergic cells, or die. Cleverly, most of the ligands for these costimulatory molecules are induced by activation/maturation of the cells that present the p ...
Astragalus membranaceus
... Client seeks herbal support 8/05, primarily to address low WBC counts but also to add another level of protection against tumor recurrence and perhaps an alternative to anti-convulsant medication ...
... Client seeks herbal support 8/05, primarily to address low WBC counts but also to add another level of protection against tumor recurrence and perhaps an alternative to anti-convulsant medication ...
Data Reveals Plant-Made Flu Vaccine Demonstrates Ability to Elicit
... poly-functional and cross-reactive T cell responses to influenza HA antigens”. The full article is available on PubMed at www.ncbi.nlm.nih.gov/pubmed/25128897. Poly-functional T-cells fight flu more effectively because they release different types of cytokines (proteins that fight pathogens and cont ...
... poly-functional and cross-reactive T cell responses to influenza HA antigens”. The full article is available on PubMed at www.ncbi.nlm.nih.gov/pubmed/25128897. Poly-functional T-cells fight flu more effectively because they release different types of cytokines (proteins that fight pathogens and cont ...
immunotherapeutic targeting of aml with a novel cd123 car
... cytotoxic potential of T cells. CARs are made up of an antigen recognition domain derived from a monoclonal antibody, linked through hinge and transmembrane domains to a costimulatory domain and a CD3ζ intracellular signaling domain. The result is a high-specificity receptor targeted against a speci ...
... cytotoxic potential of T cells. CARs are made up of an antigen recognition domain derived from a monoclonal antibody, linked through hinge and transmembrane domains to a costimulatory domain and a CD3ζ intracellular signaling domain. The result is a high-specificity receptor targeted against a speci ...
chapter 19 autoimmunity: breakdown of self-tolerance
... Breaking of the normal tolerant state of an organism's immune system may result from a variety of influences: i) Decrease in Treg activity. ii) Increase in TH activity (e.g., with adjuvants). iii) Immune response to foreign antigens which happen to cross-react with "self" (for example, the experimen ...
... Breaking of the normal tolerant state of an organism's immune system may result from a variety of influences: i) Decrease in Treg activity. ii) Increase in TH activity (e.g., with adjuvants). iii) Immune response to foreign antigens which happen to cross-react with "self" (for example, the experimen ...
Origins and means of the immune response
... •IL-4 –maturation and differentiation of B cells •IL-5 – as above but of eosinophils •IL-6 – proinflammatory, differentiating agent for B cells, •IL-7 – lymphocyte development in primary lymph organs , ...
... •IL-4 –maturation and differentiation of B cells •IL-5 – as above but of eosinophils •IL-6 – proinflammatory, differentiating agent for B cells, •IL-7 – lymphocyte development in primary lymph organs , ...
1.0MB
... innate immune system to produce signals required for an adaptive immune response Adjuvants potentiate T cell immunity by: 1. Enhancing expansion of antigen specific T cells 2. Altering antigen presentation (upregulation of costimulation). 3. Influencing differentiation of T cell subsets. ...
... innate immune system to produce signals required for an adaptive immune response Adjuvants potentiate T cell immunity by: 1. Enhancing expansion of antigen specific T cells 2. Altering antigen presentation (upregulation of costimulation). 3. Influencing differentiation of T cell subsets. ...
The worm turns - James Cook University
... T helper cell subsets: Th1, Th2, Th9, Th17 and Th22 each has an accompanying response • Th1: pro-inflammatory with TNF-α, IFN-γ, IL-12 and high levels of IgG2/3 Th1 anti-microbial response; autoimmune diseases • Th2: anti-inflammatory with IL-4, IL-5, IL-10, IL13 and higher levels of IgG4 • Th17 ...
... T helper cell subsets: Th1, Th2, Th9, Th17 and Th22 each has an accompanying response • Th1: pro-inflammatory with TNF-α, IFN-γ, IL-12 and high levels of IgG2/3 Th1 anti-microbial response; autoimmune diseases • Th2: anti-inflammatory with IL-4, IL-5, IL-10, IL13 and higher levels of IgG4 • Th17 ...
Slide 1
... – Clones of lymphocytes with different specificities are present – Total number of antigenic specificities of the lymphocytes in an individual, called the lymphocyte repertoire (107-109 distinct antigenic determinants) – Lymphocyte repertoire is called diversity ...
... – Clones of lymphocytes with different specificities are present – Total number of antigenic specificities of the lymphocytes in an individual, called the lymphocyte repertoire (107-109 distinct antigenic determinants) – Lymphocyte repertoire is called diversity ...
Cytokines
... Cytokine receptors Consisting of 2 or 3 subunits One subunit binds cytokine, other are associated with cytoplasmic signaling molecules (protein kinases) Signaling subunit is shared by several different cytokine receptors called receptor family Signaling through these receptors may lead to p ...
... Cytokine receptors Consisting of 2 or 3 subunits One subunit binds cytokine, other are associated with cytoplasmic signaling molecules (protein kinases) Signaling subunit is shared by several different cytokine receptors called receptor family Signaling through these receptors may lead to p ...
Lecture Notes: Immune System (Part I)
... I. Parts of the Immune System A. Innate or Nonspecific system 1. External body membranes like skin and mucosae i. prevents physical entry of microorganisms ii. first line of defense 2. Phagocytes, antimicrobial proteins, inflammation i. activated by chemical signals when external defenses are penetr ...
... I. Parts of the Immune System A. Innate or Nonspecific system 1. External body membranes like skin and mucosae i. prevents physical entry of microorganisms ii. first line of defense 2. Phagocytes, antimicrobial proteins, inflammation i. activated by chemical signals when external defenses are penetr ...
Vaccines Learning Module | Vaccine Education Center
... immune response to it. When a pathogen causes an immune response, it is known as an antigen. •Unfortunately, while the immune response is gaining strength, the person is likely to be ill as the struggle between the pathogen and the immune response is decided. • One part of the immune response create ...
... immune response to it. When a pathogen causes an immune response, it is known as an antigen. •Unfortunately, while the immune response is gaining strength, the person is likely to be ill as the struggle between the pathogen and the immune response is decided. • One part of the immune response create ...
Project name: Release of Neutrophil Extracellular Traps (NETs) in
... critical roles in pathogen clearance, recruitment, as well as in activation of other immune cells. To combat microbes, neutrophils employ three major strategies: the well-known (1) phagocytosis and (2) degranulation, which are beyond the scope of this research; (3) A novel host defense structure nam ...
... critical roles in pathogen clearance, recruitment, as well as in activation of other immune cells. To combat microbes, neutrophils employ three major strategies: the well-known (1) phagocytosis and (2) degranulation, which are beyond the scope of this research; (3) A novel host defense structure nam ...
Slide 1
... • Delayed-type hypersensitivity (DTH) – The reaction is antigen specific and causes swelling/thickening and redness at the site of antigen injection in immunized animals (e.g. tuberculosis skin test) ...
... • Delayed-type hypersensitivity (DTH) – The reaction is antigen specific and causes swelling/thickening and redness at the site of antigen injection in immunized animals (e.g. tuberculosis skin test) ...
File - Biology with Radjewski
... #11 b. Pathogen lands in your mouth • saliva contains lysozyme that cleaves bonds in the cell walls of many bacteria, causing them to rupture. • If bacteria move from the mouth to the nasal passages, mucus provides a line of defense. • If bacteria in the mouth are swallowed, peristaltic and ciliary ...
... #11 b. Pathogen lands in your mouth • saliva contains lysozyme that cleaves bonds in the cell walls of many bacteria, causing them to rupture. • If bacteria move from the mouth to the nasal passages, mucus provides a line of defense. • If bacteria in the mouth are swallowed, peristaltic and ciliary ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.