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The biochemistry and genetics of autoimmune disease
The biochemistry and genetics of autoimmune disease

... Figure 1. Pathogenesis of diabetic microvascular complications. This schematic proposes that the development of microvascular complications begins early in the course of diabetes, well before clinical diabetes is detected. Certain genetic characteristics or polymorphisms (Apo E4, Aldose reductase, ...
A newborn mammal has no opportunity to develop protective
A newborn mammal has no opportunity to develop protective

... in the maternal circulation, thereby preventing the activation of the mother's immune system should she conceive another Rhpositive fetus. ...
type I
type I

Immunity - Lake-Sumter State College | Home
Immunity - Lake-Sumter State College | Home

... sensitized person (see previous slide) is reexposed to the allergen (IgE mediated)  Histamine and other chemicals are released from the cells ...
The Cell-Derived Mediators of Chemical Mediators of Inflammation
The Cell-Derived Mediators of Chemical Mediators of Inflammation

... Activated macrophages Mast cells Endothelial cells • Stimulation: Bacterial endotoxins Immune complexes Products of T-lymphocytes (adaptive immune response) ...
Translating Biological Complexity Into More Powerful
Translating Biological Complexity Into More Powerful

... sustained, population-level responses. The trajectories of responses by single cells may also provide unique, timedependent signatures for immune monitoring that are less compromised by the timing and duration of ...
IMMUNODEFICIENCY
IMMUNODEFICIENCY

... • Respiratory burst is normal. • Associated with NK cell defect, platelet and neurological disorders ...
Lecture 18
Lecture 18

... – Helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism – It is part of the innate immune system that is not adaptable and does not change over the course of an individual's lifetime. – However, it can be recruited and brought into action by the ad ...
Chapter 29 (Factors Influencing Research)
Chapter 29 (Factors Influencing Research)

... 18. Deficiency of testosterone decreases the ability to biotransform xenobiotics and excess testosterone increases the ability to biotransform xenobiotics. 19. Ferrets with ovarian remnant or prolonged estrus leading to estrogen-induced bone marrow suppression, pancytopenia, and death. 20. The tempe ...
Osmoregulation, Excretion Immune System
Osmoregulation, Excretion Immune System

... 1. What are some differences between innate immunity and adaptive immunity? 2. Where can pathogens inter the body? Provide examples of barriers to pathogen entry. 3. Draw a picture or series of pictures that demonstrates what happens in the inflammatory response when bacteria get in through a cut in ...
Tibb Position on Autoimmune disease
Tibb Position on Autoimmune disease

... 2. Autoimmune  diseases  often  (but  not  always)  co-­‐exist  with  inflammation.  From  the  Tibb  perspective   inflammation  is  not  a  disease,  but  a  normal  Physis  response  to  tissue  injury,  irritation  or  metabolic   abnorma ...
Vaccination
Vaccination

... bacteria only got a mild version of the disease, and when inoculated again with fresh bacteria, they were immune. The bacteria had become attenuated. ...
14.3 Vaccination
14.3 Vaccination

... growth or numbers of dendritic cells (GM-CSF), T cell responses (IL-2). Target best APCs. ...
An Overview of Application of Artificial Immune System in Swarm
An Overview of Application of Artificial Immune System in Swarm

... has been specifically taken from Immune cells of adaptive or innate immunity. In this regard, the behaviour of neutrophils is particularly the interest of author with its potential application in Swarm Robotics. Neutrophils are the most abundant white blood cells as constitute about 40–70% of the wh ...
The immune system as the sixth sense
The immune system as the sixth sense

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... • Definition: immune response against self (auto-) antigen, by implication pathologic • General principles: – Pathogenesis: The development of autoimmunity reflects a combination of susceptibility genes and environmental triggers (usually infections) – Different autoimmune diseases may be systemic o ...
V. cholerae M. tuberculosis
V. cholerae M. tuberculosis

... Often made from: • weakened or killed microbe • its toxins • one of its surface proteins. Stimulates the body's immune system to: • recognize the agent as a threat ...
Directed Reading
Directed Reading

... cells hosting the virus would also kill surrounding healthy cells. Vaccination is the best preventative method for dealing with serious viruses. Vaccination causes the body to produce specific antibodies which resist the virus’s initial attempts to bind with healthy cells. Vaccines are used to preve ...
Lymphatic & Immune Systems
Lymphatic & Immune Systems

... List examples of physical and chemical barriers to infection. Describe how an inflammatory response can be initiated. Explain the major activities of phagocytes and natural killer cells. Discuss the three main functions of the complement system. 13.3 Adaptive Immunity Describe the major steps in the ...
Norepinephrine Inhibits Energy Metabolism of Human
Norepinephrine Inhibits Energy Metabolism of Human

... that the sensitization of α - and β -adrenoreceptors on immune cells is differentially regulated, and that these processes depend on the activation state of these cells. These findings have important implications for the understanding of stress-induced suppression of immune function and may contribu ...
Benchmark - Gulf Coast State College
Benchmark - Gulf Coast State College

... • Pathogens, cancer cells, or foreign cells have protein markers on surface (antigens) that activate the immune system because foreign to body Types of White Blood Cells - all made in the bone marrow - All called in after the non-specific WBCs –B lymphocyte cells (mature in bone marrow) • produce an ...
Benchmark - Gulf Coast State College
Benchmark - Gulf Coast State College

... • Pathogens, cancer cells, or foreign cells have protein markers on surface (antigens) that activate the immune system because foreign to body Types of White Blood Cells - all made in the bone marrow - All called in after the non-specific WBCs –B lymphocyte cells (mature in bone marrow) • produce a ...
Human Anatomy. Power Point - Panhandle Area Educational
Human Anatomy. Power Point - Panhandle Area Educational

... • Pathogens, cancer cells, or foreign cells have protein markers on surface (antigens) that activate the immune system because foreign to body Types of White Blood Cells - all made in the bone marrow - All called in after the non-specific WBCs –B lymphocyte cells (mature in bone marrow) • produce an ...
Lecture Outline 7
Lecture Outline 7

... 1. monomer with the lowest molecular mass 2. only trace amounts are found in serum 3. surface Ig on blood lymphocytes 4. may have lymphocyte activation and suppression activity e. IgE 1. slightly larger than IgG and IgA 2. involved in allergy 3. large share of antibodies formed during primary allerg ...
32_Immune responses to viruses BA
32_Immune responses to viruses BA

... 2. Killing by virus-specific CD8+ T lymphocytes – CD4+HIV+ targets 3. Syncytia formation – gp120 of infected T cells binds to uninfected T cells  fusion ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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