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Mutation Testing: An Artificial Immune System
Mutation Testing: An Artificial Immune System

... by paratopes on antibodies. However, antibodies also display epitopes of their own, known as idiotopes. A binding can now occur between antibodies, via the same mechanisms for binding with antigens. This allows interactions, creating a network structure, and thus stimulation, even in the absence of ...
Nervous System - Intermediate School Biology
Nervous System - Intermediate School Biology

... Central Nervous System: the brain and spinal cord. Describe the location and function of the following parts of the brain: cerebrum, hypothalamus, pituitary gland, cerebellum, and medulla oblongata. Describe the cross section of the spinal cord indicating the following: white matter, grey matter cen ...
Unit 08
Unit 08

... = the four stages of sexual responding described by Masters and Johnson – excitement, plateau, orgasm, and ...
2008 - Deutsche Gesellschaft für Hygiene und Mikrobiologie
2008 - Deutsche Gesellschaft für Hygiene und Mikrobiologie

... As IL-2-deficient (IL-2-/-) mice mono-colonized with E. coli develop colitis but IL-2-/- mice monocolonized with B. vulgatus do not, we investigated if stimualtion with E. coli or B. vulgatus differentially modulates distribution, activation and maturation of dendritic cells (DC) in vitro and in viv ...
Dectin 1
Dectin 1

... 1. CLEC5A inhibition during dengue virus prevents virus-induced plasma leakage and reduces mortality in mice. 2. Patients with SLE have reduced number of pDCs expressing BDCA2 that results in excessive production of type I IFNs, which is major pathophysiological factor in SLE. 3. DCIR deficiency in ...
imun-inter03 - Website Staff UI
imun-inter03 - Website Staff UI

... ° Simple columnar epithelium  M (microfold) cells – capture Ag  present their epitopes to lymphocytes ° Afferent lymph vessels (-), ° Efferent lymph drainage (+) ° Received small arterioles  capillary bed  high endothelial lined venules (HEVs) ° Lymphocytes entering Peyer’s patches have homing r ...
Equine cataracts and uveitis
Equine cataracts and uveitis

Review Immune Mechanisms in Atherosclerosis
Review Immune Mechanisms in Atherosclerosis

... plaques40 and also in the fatty streak,35 and they dominate over CD4 cells in the intimal thickening surrounding the complicated plaque.7 The CD8 subtype contains most of the cytoxic T cell activity. One possibility is that CD8 cells are involved in the initiation of the lesion, but that a switch to ...
Non-specific, B-cells, T
Non-specific, B-cells, T

Toll-Like Receptors (TLRs) and Their Ligands
Toll-Like Receptors (TLRs) and Their Ligands

... The mammalian immune system is divided into two types of immunity: innate and adaptive. Adaptive immunity is characterized by specificity and develops by clonal selection from a vast repertoire of lymphocytes bearing antigen-specific receptors that are generated by gene rearrangement. This mechanism ...
Macrophages, pathology and parasite persistence in
Macrophages, pathology and parasite persistence in

... which are necessary to kill Leishmania have been recently reviewed [2]. Of the many cytokines involved [including interferon (IFN)-g, interleukin (IL)-12, IL-4 and tumour necrosis factor (TNF)], moderate levels of TNF clearly make a major contribution to host protection in the liver, with focal TNF ...
This article appeared in a journal published by Elsevier. The
This article appeared in a journal published by Elsevier. The

... and endodermal epithelial surfaces of Hydra are continuously exposed to the environment. One litre of pond water include members from all domains of life (virus, bacteria, archaea, eukarya) and contain up to 2 billion bacteria and 1012 virus. Although the majority of microbes appear to exist in peac ...
The Lymphatic System
The Lymphatic System

Biosychology_Intro Reading
Biosychology_Intro Reading

... processes interact with emotions, cognitions and other mental processes. The field of biopsychology is related to several other areas including comparative psychology and evolutionary psychology. If you are interested in the field of biopsychology, then it is important to have an understanding of bi ...
Coagulation
Coagulation

...  Initiates physiologic clotting process  Highest concentration in brain, mucous membranes, skin, and immediately outside blood vessels  Forms "hemostatic envelope"  Not normally found on endothelial cells lining blood vessels, or on circulating blood cells ...
55. Localisation of foot-and-mouth disease virus after acute infection in cattle; a novel, immunologically significant site
55. Localisation of foot-and-mouth disease virus after acute infection in cattle; a novel, immunologically significant site

... replication. The finding of close co-localisation of viral RNA and capsid conformational epitopes, in the absence of non-structural proteins, supports the hypothesis that FMD viral particles or immune complexes are maintained in GC light zones in a non-replicating state. The results of these studies ...
III. Innate Immunity
III. Innate Immunity

... way of the blood to the red bone marrow, where they stimulate the production and release of white blood cells, primarily neutrophils. a) Dead phagocytes, dead tissue cells, dead bacteria, and living white blood cells form pus. 4. Migration of phagocytes, notably neutrophils and monocytes, also occur ...
Pathogen Associated Molecular Patterns, Pattern Recognition Receptors and Pediatric Sepsis  Lesley
Pathogen Associated Molecular Patterns, Pattern Recognition Receptors and Pediatric Sepsis Lesley

Innate immunity in the lung: how epithelial cells fight
Innate immunity in the lung: how epithelial cells fight

... of pattern recognition receptors (10 members of the human family have been recognised to date) that are represented by various members in almost all cells of the body. Their expression has been intensely studied on dendritic cells, and it is now recognised that these, TLRs, help to shape the adaptiv ...
Characterization of an immuno `stealth`derivative of the herpes
Characterization of an immuno `stealth`derivative of the herpes

... the case in those applications where the HSV-TK gene has been included in a vector as fail-safe.11,12 Under normal circumstances, the CD8 þ CTL response plays an important role in the control of virus infections, generating effector cells that kill infected cells upon recognition of viral peptides p ...
Chapter 7
Chapter 7

The Immunological Effects of Thought Suppression
The Immunological Effects of Thought Suppression

... their emotional response to a disgust-inducing film and controls. Although suppression did not affect subjective emotional reports, it produced a mixed physiological state distinguished by increased skin conductance and decreased heart rate. In a more recent study, Gross and Levenson (1997) examined ...
Prediction of Epitope and Host Organism for Generation of
Prediction of Epitope and Host Organism for Generation of

Vanessa Clark RD, LD - South Carolina Society for Respiratory Care
Vanessa Clark RD, LD - South Carolina Society for Respiratory Care

... Medical University of South Carolina ...
Intratumoral Immunization: A New Paradigm for Cancer Therapy
Intratumoral Immunization: A New Paradigm for Cancer Therapy

... value in many cancer types (Table 2). The negative prognostic value of tumor-infiltrating macrophages, tumor-associated dendritic cells (DC), and Tregs can be explained by their ability to inhibit antitumor immune responses (4). Indeed, hematocytotoxic conditioning (chemotherapy or total body irradi ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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