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Module 2: Antibodies and Antigens
Module 2: Antibodies and Antigens

... Lecture 8: Antibodies and Antigens (part II) 8.1 Characteristics of biologic antigens 1) One of the most important characters of antigen is to bind specifically to an antibody. 2) Almost all the antigens are identified by specific antibodies but very few have the ability to stimulate the antibodies. ...
Immunology and Blood Groups
Immunology and Blood Groups

... colostrum (the mother’s first milk), from which antibodies are absorbed from the intestines of the baby. Acquired passive immunity - Here, antibodies which have been made in one individual are extracted and then injected into the blood of another individual which may, or may not, be of the same spec ...
Roux P, Blenis J. ERK and p38 MAPK
Roux P, Blenis J. ERK and p38 MAPK

... recognizing self-originating danger signals which target a local immune response. Here, extracellular HSP70 has been found to act as an endogenous adjuvant, signaling the maturation of antigen presenting dendritic cells (Vabulas et al., 2002). Within the realm of neuroprotection, the role of HSP70 h ...
N E W S L E T T E R - Australasian Society for Immunology
N E W S L E T T E R - Australasian Society for Immunology

... vaccine development, I then joined Michael’s laboratory at QIMR in Brisbane where the studies on a vaccine candidate for group A streptococcal (GAS) infections were well underway. The main focus of my research project was to investigate the protection mechanisms, including memory responses, employed ...
Proceedings of the Indiana Academy of Science
Proceedings of the Indiana Academy of Science

... Aerobacter aero genes were added to serve as a source of food. The cultures were maintained at a temperature of 27° ± 1° C. It was unnecessary to handle the flask cultures aseptically. Each culture was used when 3-5 days old. At the time the paramecia were to be used, they were aggregated in a dense ...
Feline Leukemia Virus Diseases.rtf
Feline Leukemia Virus Diseases.rtf

... How are cats with leukemia treated? Some forms of leukemia (blood cancer) are unresponsive to all available forms of cancer treatment. Other types of leukemias may respond to chemotherapy, though most of these have an average survival time of less than one year. Because the virus is not affected by ...
LECTURE: 09 T- LYMPHOCYTES PRODUCTION AND
LECTURE: 09 T- LYMPHOCYTES PRODUCTION AND

... The two main types of lymphocytes are known as T and B cells. These two types of lymphoid cells are developed and differentiated in the primary lymphoid organs. For example, T cells are developed in the thymus, where as the B lymphocytes are differentiated in the adult bone marrow and fetal liver. I ...
7th seminar 2013 Complement system
7th seminar 2013 Complement system

Chapter 21a
Chapter 21a

... Mature into fully functional antigen-activated cells upon binding with ...
B7x/B7-H4 modulates the adaptive immune response and
B7x/B7-H4 modulates the adaptive immune response and

... endogenous retrovirus subfamily H (HERV-H) LTRassociating protein 2 (HHLA2) [5] inhibit T cell proliferation and activation as well as cytokine release [6,7]. T cells express CD28, cytotoxic T lymphocyte antigen-4 (CTLA-4), PD-1 and ICOS which bind to B7 members present on APC, leading to activating ...
Nature of Immunity - Napa Valley College
Nature of Immunity - Napa Valley College

... Protect against invading organisms Removing damaged cells from the circulation Serve as a surveillance network for recognizing and guarding against the development and growth of abnormal cells ...
Autoimmune diseases
Autoimmune diseases

... Autoimmune Hepatitis (AIH) and Dermatology diseases Collect pediatric patients treated with AZA Evaluate efficacy, toxicity - Investigate therapeutic range of 6-TGN level - Optimize AZA dose for children with these diseases ...
A Possible Link Between Autoimmunity and Cancer
A Possible Link Between Autoimmunity and Cancer

... immune response in cancer, immature pDCs are activated by Toll-like receptors, which lead to B- and T-cell immune responses in autoimmune disease (Lang et al., 2005). The immunological tolerance is produced by tumour-derived soluble factors (TDSFs) and immature dendritic cells (iDCs), which inhibit ...
21 - Dr. Jerry Cronin
21 - Dr. Jerry Cronin

... molecules. Host cell 1 Infected by virus; makes interferon; is killed by virus © 2013 Pearson Education, Inc. ...
Cells in Gut-Oriented Immune Responses The Role of Dendritic
Cells in Gut-Oriented Immune Responses The Role of Dendritic

... nization with the original fed Ag (17). Both the transferable suppression and the bystander effect have been associated with Th3 cells producing TGF-␤, as well as with Th2 cells that produce IL-4 and IL-10 (18), although subsequent high-dose feeding may change these characteristics (19). Thus, the r ...
Part III, Endotoxin Test Concerns of Biologics
Part III, Endotoxin Test Concerns of Biologics

ch_21_lecture_presentation_a
ch_21_lecture_presentation_a

Helminth infections: The structure trans
Helminth infections: The structure trans

Total white blood cell counts and LPS-induced TNFa
Total white blood cell counts and LPS-induced TNFa

... We have performed three separate experiments to evaluate the effect of freezing upon monocyte TNFa production. Therefore, blood was taken from a rat in the follicular phase and stimulated with endotoxin as described above. In each experiment, two stimulated and two unstimulated samples were frozen a ...
What is Tangier DISEASE?
What is Tangier DISEASE?

... body is not processed correctly. This causes cholesterol to build up in certain tissues of the body causing the symptoms associated with Tangier Disease. Tissues affected include the tonsils, thymus, lymph nodes, bone marrow, liver, intestines, immune system cells such as macrophages, cornea of the ...
PowerPoint to accompany
PowerPoint to accompany

the printed Meeting Program
the printed Meeting Program

Ectopic lymphoid-like structures in infection, cancer and autoimmunity
Ectopic lymphoid-like structures in infection, cancer and autoimmunity

... or non-resolving episodes of inflammation lead to the inappropriate regulation of this response and promote autoimmunity, chronicity and tissue pathology1,3,4. The mechanisms that control these events are often diverse and they contribute to clinical differences in disease presentation. For example, ...
B Cells and Antibodies
B Cells and Antibodies

... discovered, although it is thought to have something to do with changing the conformation of the cell’s DNA so that it no longer is accessible to the cut-and-paste machinery. Since each player only has about a one in nine chance of success, you may be wondering what happens if both chromosomes fail ...
Decreased FOXP3 expression in small airways of smokers with COPD
Decreased FOXP3 expression in small airways of smokers with COPD

... virus-associated mixed cryoglobulinaemia, autoimmune liver disease, systemic lupus erythematosus and Kawasaki disease [6, 11]. Low levels of circulating CD4+CD25+ T-cells also correlate with a higher disease activity or poor prognosis. It has been proposed that downregulation of Treg cells may be ca ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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