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Functions of T lymphocytes
Functions of T lymphocytes

Signatures in HIV-1 Infection Reveals Stage
Signatures in HIV-1 Infection Reveals Stage

... Untreated HIV-1 infection progresses through acute and asymptomatic stages to AIDS. Although each of the three stages has well-known clinical, virologic, and immunologic characteristics, much less is known of the molecular mechanisms underlying each stage. In this study, we report lymphatic tissue m ...
the innate immunity in bovine mastitis
the innate immunity in bovine mastitis

... The innate immune system represents the first line of defense in the host response to infection and is poised to immediately recognize and respond to the earliest stages of infection. The inherent capability of the innate system to respond to a vast number of pathogens is mediated by its ability to ...
Hypersensitivity Associated with Metallic Biomaterials
Hypersensitivity Associated with Metallic Biomaterials

... metals, in the case of dermal contact (in which dermal Langerhans cells are the primary hypersensitivity effector cells), is probably different from the periprosthetic in vivo environment (36,53). In addition, the diagnostic utility of patch testing may be affected by possible immunological toleranc ...
Level 3 Pharmaceutical Science
Level 3 Pharmaceutical Science

... nerves. They act together, communicating and carrying information to the brain, and instructions from it. There are two divisions of the nervous system:  Brain and spinal cord forming the central nervous system  Peripheral nervous system which connects the CNS to limbs and organs Nerves carry elec ...
HIV/AIDS
HIV/AIDS

Mechanisms of Immune Evasion by Tumors
Mechanisms of Immune Evasion by Tumors

... tumors, the major pathophysiologic characteristics of malignant cancer responsible for morbidity and mortality are the ability to invade across natural tissue barriers and to metastasize. Both of these characteristics, which are never seen with normal tissues or benign tumors, are associated with dr ...
| Specific antigen(s) in sarcoidosis: a link to autoimmunity?
| Specific antigen(s) in sarcoidosis: a link to autoimmunity?

... was weakened when bacterial DNA was identified in sarcoidosis lesions [8, 9]. The results presented by these authors suggest that microorganisms such as propionibacteria and mycobacteria are either the cause or at least an important cofactor in the pathogenesis of sarcoidosis. In this issue of the E ...
brain regeneration in physiology and pathology: the immune
brain regeneration in physiology and pathology: the immune

... nervous and the immune systems. In the light of this, we will elaborate on when and how the cross-talk between neural stem/progenitor cells (NPCs) and CNS-resident and infiltrating blood-borne immune cells foster or hamper tissue repair. Here, we will use “NPCs” as a generic term encompassing the fo ...
Overtraining Syndrome
Overtraining Syndrome

... Neural and Endocrine Factors • Overtraining stressors may act primarily through hypothalamic signals – Can lead to sympathetic neural activation – Can lead to pituitary endocrine cascade ...
Chapter 3 Pro-Inflammatory Cytokines and Cardiac Extracellular
Chapter 3 Pro-Inflammatory Cytokines and Cardiac Extracellular

... contributor to structural remodeling of the injured or failing myocardium. MMP activation and net ECM degradation may be proximal responses to the acute elevation of pro-inflammatory cytokines in response to injury. This phase is followed by compensatory collagen resynthesis, ultimately leading to c ...
Chapter 21 PowerPoint - Hillsborough Community College
Chapter 21 PowerPoint - Hillsborough Community College

... 1. Leukocytosis: release of neutrophils from bone marrow in response to leukocytosis-inducing factors from injured cells 2. Margination: neutrophils cling to the walls of capillaries in the inflamed area 3. Diapedesis of neutrophils ...
Basic Components: Structure and Function
Basic Components: Structure and Function

... large number of V genes and the way in which these may be combined with different D and J genes to provide different V domain genes. The similarities between TCRs and BCRs have led to the suggestion that the genes evolved from the same parent gene and both are members of a ‘supergene’ family. Unlike ...
Neurons & the Nervous System
Neurons & the Nervous System

... phase” when a neuron, after firing, cannot generate another action ...
COLOSTRUM THE WHITE GOLD DISCOVERY
COLOSTRUM THE WHITE GOLD DISCOVERY

Innate or Adaptive Immunity? The Example of Natural Killer Cells
Innate or Adaptive Immunity? The Example of Natural Killer Cells

... tion of NK cells has been revisited. NK cells X1 patients and in mice lacking IL-15 or IL-15R the redundancy of NK cell developmental pathrequire priming by various factors, such as IL- components (21). Cytokine receptors that are ways and may explain the robustness of this 15 presented by DC (15) o ...
Amino Acids : beyond the building blocks
Amino Acids : beyond the building blocks

... Amino acids and intestinal physiology The gastrointestinal tract, while representing only 4-6 % of body mass, accounts for 2550% of whole body protein turnover. The extraction of essential dietary amino acids by the gut might represent 20-70%. Burrin and coll showed that 60-90% of threonine intake w ...
Chapter 21a
Chapter 21a

... Mature into fully functional antigen-activated cells upon binding with their recognized antigen ...
The Nervous System  - Home
The Nervous System - Home

... Lobes of the brain The average human brain weighs about 1,400 grams (3 lb). When the brain is removed from the skull, it looks a bit like a large pinkish-gray walnut. The brain can be divided down the middle lengthwise into two halves called the cerebral hemispheres. Each hemisphere of the cerebral ...
department of molecular biology and immunology
department of molecular biology and immunology

... Infectious diseases have a major impact on health around the world. New infectious agents have emerged, and diseases caused by known pathogens have reestablished themselves. Many of these infections result in life-threatening diseases. To complicate matters, many of these infectious agents have deve ...
Role and therapeutic value of dendritic cells in central
Role and therapeutic value of dendritic cells in central

... immune-mediated diseases, particularly for the re-establishment of antigen-specific tolerance. However, these drugs were not specifically designed to target DCs and obviously affect many cell types and biological processes in vivo, potentially leading to unwanted side effects. Thus the study of the ...
poliomelitis 2010-20112011-09-11 10:50673 KB
poliomelitis 2010-20112011-09-11 10:50673 KB

... surveillance for communicable diseases in a systematic way. ...
The pathogenesis of influenza virus infections: the contributions of
The pathogenesis of influenza virus infections: the contributions of

... infection is mainly limited to the upper respiratory tract, the disease is mild. Nonetheless, the viruses spread easily among human populations mediated by nasal discharges that contain high titers of live virus. Highly pathogenic avian H5N1 influenza viruses (HPAIV), however, preferentially recogni ...
Graves` Disease - American Thyroid Association
Graves` Disease - American Thyroid Association

... • Immune System Graves’ disease is triggered by some process in the body’s immune system, which normally protects us from foreign invaders such as bacteria and viruses. The immune system destroys foreign invaders with substances called antibodies produced by blood cells known as lymphocytes. Some ...
PATHOGENESIS OF AN EMERGING PATHOGEN – CRIMEAN
PATHOGENESIS OF AN EMERGING PATHOGEN – CRIMEAN

... transepithelial electrical resistance (TER) over infected epithelial cells, and showed that CCHFV replication has no direct effect on epithelial permeability. Furthermore, we observed no effect of CCHFV on the localization of the TJ proteins occludin and ZO-1 in epithelial cells. Interestingly, CCHF ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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