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Barrier Animal Care Clinic - shar
Barrier Animal Care Clinic - shar

Activation, Differentiation, and Cell Death on Murine Chromosome 7
Activation, Differentiation, and Cell Death on Murine Chromosome 7

... Polyclonal, generalized T cell defects, as well as Ag-specific Th clones, are likely to contribute to pathology in murine lupus, but the genetic bases for these mechanisms remain unknown. Mapping studies indicate that loci on chromosomes 1 (Sle1), 4 (Sle2), 7 (Sle3), and 17 (Sle4) confer disease sus ...
Immunomodulation of pathogen-host interactions
Immunomodulation of pathogen-host interactions

... mycoplasmas and affinity resins that are specific for different lipid and carbohydrate moieties on the mycoplasma membranes. In Experiment 4, we have described synergistic effect of TLR agonist molecules, such as peptidoglycan (TLR-2/Nod2) and bacterial DNA (TLR-9) on the stimulation of the innate i ...
Non infectious dermatoses
Non infectious dermatoses

Laboratory of Viral Immunology
Laboratory of Viral Immunology

...  Familial association (Kimani)  Kindered of HIV-R more likely to remain HIV-negative (Kimani, Ball)  Polymorphisms associated with resistance, e.g. IRF-1 (Ji, Ball) ...
Sondel PM, Hank JA, Wendel T, Flynn B and Bozdech MJ. HLA
Sondel PM, Hank JA, Wendel T, Flynn B and Bozdech MJ. HLA

cystic fibrosis lecture
cystic fibrosis lecture

... were placed on apical surface of cells * bacteria flourished on CF cultures but were killed on normal cultures; bacteria placed on basolateral surface killed both * if pure water was added to apical side of CF cultures, they were able to kill the bacteria (evidence of a salt-sensitive factor, defens ...
Neutrophil function in the healing wound: adding insult to injury?
Neutrophil function in the healing wound: adding insult to injury?

MR Presentation
MR Presentation

... against six killer diseases of childhood, before then, provided on an adhoc basis through schools and the larger health facilities  Therefore concentrated initially on establishing and strengthening the ...
Cytokines That Promote Periodontal Tissue Destruction
Cytokines That Promote Periodontal Tissue Destruction

... Although periodontal diseases are initiated by bacteria that colonize the tooth surface and gingival sulcus, the host response is believed to play an essential role in the breakdown of connective tissue and bone, key features of the disease process. An intermediate mechanism that lies between bacter ...
Sample pages 1 PDF
Sample pages 1 PDF

... vesicles, and other parts of the cell membranes to and from the soma down the axon to the synapses and back up to the soma. Microtubules provide the structural basis for transport, axoplasmic flow. This mechanism of transport is not diffusion but rather retrograde axonal transport associated with th ...
HEALTH PSYCHOLOGY: Mapping Biobehavioral Contributions to
HEALTH PSYCHOLOGY: Mapping Biobehavioral Contributions to

... of data from studies of health and behavior strongly suggests that psychological processes and emotional states influence the etiology and progression of disease and contribute to overall host resistance or vulnerability to illness. In general, psychosocial or behavioral factors exert their influenc ...
Chapter 21 PowerPoint
Chapter 21 PowerPoint

ADC Immunogenicity Testing Strategy
ADC Immunogenicity Testing Strategy

... One of the challenges with novel protein therapeutics including pegylated compounds, glycosylated compounds, and antibody-drug conjugates, is understanding how the human immune system will respond. As we advance more of these novel therapeutics we will have the opportunity, through careful character ...
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item[`#file`]

...  Megaloblastic Anemia – Fe deficiency affects platelet production…  Hereditary Disorder – involve decreasing megakaryocytes or producing bad megakaryocytes Immune Thrombocytopenias  Autoimmune thrombocytopenia – antibodies produced against platelets: o Acute – more common in children, preceded by ...
Lecture6 - Part 1 ANS student (2012).
Lecture6 - Part 1 ANS student (2012).

... (3) Hind brain: Pons, Medulla , Cerebellum B/Spinal cord ...
Immunopathology of Sepsis - American College of Veterinary
Immunopathology of Sepsis - American College of Veterinary

... Cytokine storm. Previously it was believed that sepsis was due to the rapid, explosive production of cytokines resulted in “cytokine storm”. This cytokine storm resulted in overwhelming inflammation and tissue injury. The concept was that the host did not die from the bacterial infection, but rathe ...
Fig 5 - Journal of Allergy and Clinical Immunology
Fig 5 - Journal of Allergy and Clinical Immunology

... compared with that seen at GPSI but remained higher than at time 0 (Fig 2, B). During the second year, there was no increase in the frequency of these cells in or out of GPSII; indeed, the lowest IL-51 cell frequency was registered during this period (Fig 2, B). These findings suggest that SLIT supp ...
Glia Ç more than just brain glue
Glia Ç more than just brain glue

... occur between neurons and astrocytes. Individual astrocytes can make contact with and ensheath thousands of synapses formed between many different neurons. This means that synapses don’t consist of just a pre- and postsynaptic neuronal element, but that many also have an astrocytic projection that e ...
Chapter_24_HB_Immune
Chapter_24_HB_Immune

Human Immunodeficiency Virus Pathogenesis
Human Immunodeficiency Virus Pathogenesis

... helper cells can then facilitate humoral and cellular immune responses against the invading pathogen. HIV-specific T cells interact with antigen-specific B cells on the border of lymphoid follicles in the cortex, and B cell proliferation results in follicular hyperplasia. This interaction results in ...
Function of Skin - Moore Public Schools
Function of Skin - Moore Public Schools

... 4) Feel pain, pressure, and temperature Structures in the Skin that do this Function Nerve tissue Example of this Function When you touch something, nerves of skin sense environment ...
Oils that contain Phenols
Oils that contain Phenols

Use of Stem Cells for Autism Treatment
Use of Stem Cells for Autism Treatment

... (2) differentiation process: through it, the cells give rise to more differentiated cells; (3) paracrine regulatory functions: stem cells synthesize and release a complex and implantable “biopharmacy,” capable of regulating cell differentiation, tissue and organ repair, and anti-inflammatory actions ...
The avian lung-associated immune system: a review
The avian lung-associated immune system: a review

... Abstract – The lung is a major target organ for numerous viral and bacterial diseases of poultry. To control this constant threat birds have developed a highly organized lung-associated immune system. In this review the basic features of this system are described and their functional properties disc ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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