b - Repositório da Universidade de Lisboa
... that sends me emails with passages from his diary making me go back to my childhood; to my mother for all the weekend chats; to my aunt Luisa that always dropped a message to make sure I am ok; to my uncle Zé e Rita that are always ready to hear me out and advise me on what best to do; to Teresa tha ...
... that sends me emails with passages from his diary making me go back to my childhood; to my mother for all the weekend chats; to my aunt Luisa that always dropped a message to make sure I am ok; to my uncle Zé e Rita that are always ready to hear me out and advise me on what best to do; to Teresa tha ...
Epicor - Doctor`s Best Vitamins
... yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled trial. Adv Therapy 2009;26:795-804. 7. Jensen GS, Patterson KM, Barnes J, others. A double-blind, placebo-controlled, randomized pilot study: Consumption of a high-meta ...
... yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled trial. Adv Therapy 2009;26:795-804. 7. Jensen GS, Patterson KM, Barnes J, others. A double-blind, placebo-controlled, randomized pilot study: Consumption of a high-meta ...
- Journal of Clinical Investigation
... The Journal of Clinical Investigation ticular autologous peptides (14). Benign low-level autoimmunity to self-proteins is probably near ubiquitous and may be critical for maintaining immunological homeostasis. In some cases, however, self-reactive immune responses become profoundly dysregulated, ...
... The Journal of Clinical Investigation ticular autologous peptides (14). Benign low-level autoimmunity to self-proteins is probably near ubiquitous and may be critical for maintaining immunological homeostasis. In some cases, however, self-reactive immune responses become profoundly dysregulated, ...
determining the innate and adaptive immune responses to vesicular
... The goal of this research project is to determine the response of dendritic cells and T cells to vesicular stomatitis virus (VSV) vectors that express flagellin. VSV is currently in clinical trials as a recombinant vaccine vector against heterologous antigens (1). Incorporating flagellin gene into t ...
... The goal of this research project is to determine the response of dendritic cells and T cells to vesicular stomatitis virus (VSV) vectors that express flagellin. VSV is currently in clinical trials as a recombinant vaccine vector against heterologous antigens (1). Incorporating flagellin gene into t ...
Biological Activities of Complement
... the presence of CaZCand MgZ+, by the formation of an immune complex between immunoglobulin M or G and antigen, here shown as an antigenic site on a cell surface. This binding process in turn activates the complement components C1, C4, C2 and C3. Activation of components C1 and C2 results in the gene ...
... the presence of CaZCand MgZ+, by the formation of an immune complex between immunoglobulin M or G and antigen, here shown as an antigenic site on a cell surface. This binding process in turn activates the complement components C1, C4, C2 and C3. Activation of components C1 and C2 results in the gene ...
Chapter 21 - El Camino College
... Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings ...
... Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings ...
Bovine Endometrial Epithelial Cells Scale Their Pro
... (PLO), which causes cytolysis of host cells (Jost et al., 1999; Amos et al., 2014). Moreover, T. pyogenes expresses a number of known and putative virulence factors, which may be involved in adhesion to host cells (Jost and Billington, 2005). Furthermore, T. pyogenes could trigger a pro-inflammatory ...
... (PLO), which causes cytolysis of host cells (Jost et al., 1999; Amos et al., 2014). Moreover, T. pyogenes expresses a number of known and putative virulence factors, which may be involved in adhesion to host cells (Jost and Billington, 2005). Furthermore, T. pyogenes could trigger a pro-inflammatory ...
Activation of the Cellular Immune Response in
... assaults from non-self to “live long and prosper”. The discipline of immunology was founded by Elie Metchnikoff and Paul Ehrlich who were awarded the Nobel Prize in 1908 “in recognition for their work on immunity” Metchnikoff´s discovery of phagocytosis spawned innate immunity and Ehrlich´s side-cha ...
... assaults from non-self to “live long and prosper”. The discipline of immunology was founded by Elie Metchnikoff and Paul Ehrlich who were awarded the Nobel Prize in 1908 “in recognition for their work on immunity” Metchnikoff´s discovery of phagocytosis spawned innate immunity and Ehrlich´s side-cha ...
Chimeric CLL-1 Antibody Fusion Proteins Containing Granulocyte
... tumor regressions in patients with relapsed B-cell non-Hodgkin’s lymphoma (NHL),1 unconjugated MoAbs have demonstrated limited therapeutic responses.2 Radioimmunotherapy, on the other hand, has shown considerable promise in clinical studies, particularly in the treatment of B-cell NHL.3 The efficacy ...
... tumor regressions in patients with relapsed B-cell non-Hodgkin’s lymphoma (NHL),1 unconjugated MoAbs have demonstrated limited therapeutic responses.2 Radioimmunotherapy, on the other hand, has shown considerable promise in clinical studies, particularly in the treatment of B-cell NHL.3 The efficacy ...
Dendritic cells in progressive renal disease: some answers, many
... in that they are functionally specialized to sense foreign or altered nucleic acids and produce Type I interferons as well as presenting antigens. Classical DCs reside in secondary lymphoid organs and in peripheral tissues. Different tissues possess DCs with different functions, best suited to their ...
... in that they are functionally specialized to sense foreign or altered nucleic acids and produce Type I interferons as well as presenting antigens. Classical DCs reside in secondary lymphoid organs and in peripheral tissues. Different tissues possess DCs with different functions, best suited to their ...
Tissue specific HPV expression and downregulation of local
... by RT-PCR in biopsies of penile and perianal condylomas. Linear regression was done using SIGMASTAT statistical software. (B) HPV E7 mRNA levels were also compared with Langerhans cell (CD1a) mRNA content. ...
... by RT-PCR in biopsies of penile and perianal condylomas. Linear regression was done using SIGMASTAT statistical software. (B) HPV E7 mRNA levels were also compared with Langerhans cell (CD1a) mRNA content. ...
Arthritis an autoimmune disorder: Demonstration of In
... Smt. R. B. P. M. Pharmacy College, Atkot-360040, Rajkot, Gujarat. India Abstract In the normal knee jo int, the synovium consists of a synovial membrane (usually one or two cells thick) and underlying loose connective tissue. Synovial-lin ing cells are designated type a (macrophage-like synoviocytes ...
... Smt. R. B. P. M. Pharmacy College, Atkot-360040, Rajkot, Gujarat. India Abstract In the normal knee jo int, the synovium consists of a synovial membrane (usually one or two cells thick) and underlying loose connective tissue. Synovial-lin ing cells are designated type a (macrophage-like synoviocytes ...
Induced disruption of the transforming growth factor
... Transforming growth factor beta (TGF-) is recognized as a highly pleiotropic family of growth factors involved in the regulation of numerous physiologic processes including development, hematopoiesis, wound healing, and immune response. The 3 isoforms of this growth factor that have been identified ...
... Transforming growth factor beta (TGF-) is recognized as a highly pleiotropic family of growth factors involved in the regulation of numerous physiologic processes including development, hematopoiesis, wound healing, and immune response. The 3 isoforms of this growth factor that have been identified ...
Persistence of Mycoplasmal Infections and Various Clinical Conditions
... Mycoplasma interactions with host immune systems Certain Mycoplasma species can either activate or suppress host immune systems, and they may use these activities to evade host immune responses. For example, some mycoplasmas can inhibit or stimulate the proliferation of normal lymphocyte subsets, in ...
... Mycoplasma interactions with host immune systems Certain Mycoplasma species can either activate or suppress host immune systems, and they may use these activities to evade host immune responses. For example, some mycoplasmas can inhibit or stimulate the proliferation of normal lymphocyte subsets, in ...
Complement in the Brain
... entry of blood borne cells and proteins into the central nervous system (CNS). As a result, the detection and clearance of invading microorganisms and senescent cells as well as surplus neurotransmitters, aged and glycated proteins, in order to maintain a healthy environment for neuronal and glial c ...
... entry of blood borne cells and proteins into the central nervous system (CNS). As a result, the detection and clearance of invading microorganisms and senescent cells as well as surplus neurotransmitters, aged and glycated proteins, in order to maintain a healthy environment for neuronal and glial c ...
Review - International Federation of Cell Therapy Professionals
... human keratinocytes were shown to be 100-fold more efficient and 2-fold faster at generating iPSCs when compared with other human fibroblasts.46 Also, hematopoietic stem cells were found to be 300× more efficient at iPSC generation when compared with mature T/B cells.47 These results are in agreemen ...
... human keratinocytes were shown to be 100-fold more efficient and 2-fold faster at generating iPSCs when compared with other human fibroblasts.46 Also, hematopoietic stem cells were found to be 300× more efficient at iPSC generation when compared with mature T/B cells.47 These results are in agreemen ...
Full Text Article - European Journal of Pharmaceutical and Medical
... Microbial infection is a very serious problem and Living beings protect themselves from infectious organisms by various defense mechanisms called as immune system. Complement system (CS) is a part of innate immune system, consist of nine proteins denoted by C1-C9 which are present in human beings an ...
... Microbial infection is a very serious problem and Living beings protect themselves from infectious organisms by various defense mechanisms called as immune system. Complement system (CS) is a part of innate immune system, consist of nine proteins denoted by C1-C9 which are present in human beings an ...
Trinity™ Multipotential Cellular Bone Matrix
... reproductive, and urinary systems. MSCs are developmentally intermediate to embryonic stem cells and terminallydifferentiated adult cells.14,44 It is as a result of their relatively “young” biological age that MSCs can serve as an in situ source of osteoprogenitor cells throughout a lifetime.14 Whet ...
... reproductive, and urinary systems. MSCs are developmentally intermediate to embryonic stem cells and terminallydifferentiated adult cells.14,44 It is as a result of their relatively “young” biological age that MSCs can serve as an in situ source of osteoprogenitor cells throughout a lifetime.14 Whet ...
Innate immune system
The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑