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... cells; these also kill off antigens that have been labeled as targets by antibodies Pathogens: harmful organisms and viruses that can cause disease Phagocytes: WBC; defense cells that circulate the body and work to eliminate invaders through phagocytosis Plasma cells: formed from B cells; they synth ...
lecture08_C
lecture08_C

...  Recognizes antigens (molecular signatures) specific for each pathogen  Effective against both intra- and extracellular pathogens  Two main components: Humoral immunity - Relies on Antibodies produced by B-lymphocytes - Fights pathogens outside of cells ...
Pathogens and the immune system
Pathogens and the immune system

... ƒ Two main components: Humoral immunity - Relies on Antibodies produced by B-lymphocytes - Fights pathogens outside of cells ...
Review questions for Immune System
Review questions for Immune System

... 17. What role do prostaglandins play in inflammation? What role do they play in homoestasis? ...
Content Benchmark L.12.B.3 1
Content Benchmark L.12.B.3 1

... Students know disease disrupts the equilibrium that exists in a healthy organism. E/S 1st Item Specification: Evaluate how a disease disrupts the homeostasis of an organism. Depth of Knowledge Level 1 1. The process by which organisms maintain a stable internal environment is called A. homeostasis. ...
Bio07_TR__U10_CH40.QXD
Bio07_TR__U10_CH40.QXD

... 14. Circle the letter of each sentence that is true about elevated body temperature. a. It kills many pathogens. b. It speeds up the action of white blood cells. ...
The Immune System
The Immune System

... • Lymphocytes that mature in the thymus (胸腺) above the heart are called T cells, and those that mature in bone marrow are called B cells ...
Challenge Biomedical Science – Immunology The Immune
Challenge Biomedical Science – Immunology The Immune

... invader and destroy it. T Cells identify and destroy any human cells which may have died or changed or those which it recognises as non-human. Some B & T cells produced live on after the first attack and help the body fight against a second attack should it occur. You are therefore immune to these b ...
Natural Killer Cells
Natural Killer Cells

... Neutrophils- found throughout body, in blood. Phagocytosis of Ab-Ag CX Macrophages- throughout body, blood, lymphatics ...
Functions of the Immune System
Functions of the Immune System

... the nose hairs and the moist mucous membranes lining the respiratory system. The tonsils (lymphatic system) also form a protective ring around the throat. If foreign matter gets past these barriers, coughing and sneezing help to expel it from the respiratory system. ...
Organism Physiology Immunity
Organism Physiology Immunity

... 3. How is immunity acquired during a vertebrate’s life cycle? 4. Compare B-cells and T-cells. 5. How is it possible that functionally infinite variations of antibodies can be made from one set of genes? 6. Explain the role of Helper T-cells in the immune system. 2nd Interact: Watch Mr. Anderson’s Im ...
Diphtheria Toxin and Engineered Receptor
Diphtheria Toxin and Engineered Receptor

... Immunologists are using diphtheria toxin (DT) in studies to sort out the function of various immune cells. Diphtheria toxin is a potent inhibitor of protein synthesis and will kill about any cell to which it gains entry. Diphtheria toxin receptor (DTR), either simian or human, is genetically attache ...
Immune responses in viral infections
Immune responses in viral infections

... phagocytes ingest and attempt to destroy it. Phagocytosis occurs initially by ‫٭‬neutrophils and later by ‫٭‬macrophages, intracellular bacteria are resistant to degradation within phagocytes. ‫٭‬NK cells function by two means direct killing of infected cells and by activating of macrophages through ...
PowerPoint 簡報
PowerPoint 簡報

... - constitutively cytotoxic, always having large granules - involved in the defense against viruses and tumors - Activity is stimulated by IFNa, IFNb, and IL-12. - express CD16 (FcgRIII) - do not express TCR/CD3 - Recognition is not MHC-restricted. - normal in RAG-1, RAG-2, and SCID mice - Cytotoxici ...
tib3handout_me
tib3handout_me

... Group of approx. 30 serum proteins, main function is control of inflammation but also mediate phagocytosis and interact with antibodies – antibodies label, complement destroys Complement activation is a cascade reaction Inactive until becomes activated and cleaved by proteases 2 pathways: Classical ...
The Inflammatory Response
The Inflammatory Response

... Acute inflammation: the normal Inflammatory response ●neutrophils dominate. ●you feel and see it (pain, redness, swelling, heat). ●Inflammatory cytokines are expressed and do their job and resolution occurs relatively quickly –it’s over and done with. ...
Immune Primer - Life Sciences Outreach Program
Immune Primer - Life Sciences Outreach Program

... movie of the inflammatory response you must choose Inflammation Movie from the top of the list. 14. What enters the body with a knife to generate an inflammatory response? 15. What chemical is released from damaged cells? 16. Blood cells diffuse into capillaries and cause the blood vessels to dilate ...
Ch21A - MDC Faculty Home Pages
Ch21A - MDC Faculty Home Pages

... ________________________________ with one another so that the whole system mounts a _____________________ response. (Slide #75) In ________________________ Immunity, the antigen challenge is the __________________ encounter between an antigen and a naive immunocompetent lymphocyte. This usually occu ...
Chapter 3 Review Answers
Chapter 3 Review Answers

Reading Chapter 27 NERVOUS SYSTEM Neurons
Reading Chapter 27 NERVOUS SYSTEM Neurons

... bloodstream. The virus circulates free in the plasma and comes in contact with the target cells. These viruses may cause mild systemic infections because of the inflammation due to induction of interferon. (like rhinoviruses) SLEEPING SICKNESS -caused by Trepansoma brucei, a flagellated protozoan - ...
LYMPHATIC SYSTEM
LYMPHATIC SYSTEM

...  Phagocytes – engulfs a foreign particle and uses digestive enzymes to break down the particle…macrophages and neutrophils are phagocytes  Natural Killer Cells – unique type of lymphocyte that can destroy cancer cells and virus-infected cells before the immune system is needed. These cells monitor ...
No Slide Title
No Slide Title

... My body is not able to maintain homeostasis because it is too cold, my fingers and toes are discolored and numb, my blood has surrounded my main organs to keep them alive, what non-homeostatic state is my body in? ...
Immune responses against a virus-related skin
Immune responses against a virus-related skin

LEUKOPOIESIS LEARNING OBJECTIVES • To classify the different
LEUKOPOIESIS LEARNING OBJECTIVES • To classify the different

... Have red-staining, bilobed nuclei connected via a broad band of nuclear material Have red to crimson (acidophilic) large, coarse, lysosome-like Basophils granules Lead the body’s counterattack against parasitic worms Also involves in allergic reactions ...
Body Defenses and Diseases ppt
Body Defenses and Diseases ppt

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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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