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... substances e.g. pollen, dust. • When the immune system over reacts B lymphocytes are activated producing antibodies which attach to the mast cells in the connective tissue causing the release of histamine • Excessive histamine stimulates the inflammatory response ...
PP - The Lymphatic System
PP - The Lymphatic System

... Non-self- proteins that the body does not recognize ...
topic 11 notes
topic 11 notes

... • A muscle fiber is a muscle cell. • There are 3 types of muscle, smooth, cardiac and skeletal. • Skeletal muscle cells are highly modified for contraction, so their cell structure is different than most cells. • Muscle cells are called muscle fibers because of their elongated shape. ...
Ch21B
Ch21B

... variation through _____________________________. Each Plasma cell can switch the type of Heavy chain produced, making an antibody of a __________________________________. (Slide #12) Antibodies inactivate and tag antigens by forming ______________________________________ (immune) complexes. What are ...
Week 1
Week 1

The Immune System Second Edition
The Immune System Second Edition

... TH1 cells recognizing a specific antigen present within the joint triggers them to release inflammatory cytokines to initiate local inflammation plasma cells make a IgM, IgG and IgA that binds to the Fc region of patients’ own IgG - called rheumatoid factor (RF). These are deposited in the joints an ...
Immunology: Basic Principles of Adaptive Immunity and Immunizations
Immunology: Basic Principles of Adaptive Immunity and Immunizations

... Attaches to the lining of the digestive, respiratory, and gastrointestinal tract Transported through epithelial cells Attaches to microbes before they invade tissues Activates complement Exists as a dimer ...
Immunology: Introduction and Overview
Immunology: Introduction and Overview

... In the innate system, glyocproteins and glycolipids are more stimulatory than are proteins which is in contrast to the adaptive system where proteins are more stimulatory. Effector mechanisms of innate immunity include; anatomic and physiologic barriers like skin and mucous membranes, phagocytosis, ...
The Immune System
The Immune System

... previous encounters with disease-causing germs (for example, the virus that caused the measles you had as a child) and knows how to defend against these threats. It also learns how to respond to invaders it hasn’t seen before, by developing specific defences against them. ...
Defense Against Disease
Defense Against Disease

... Blood contains white blood cells which kill any micro-organisms within the body ...
Chapter 21
Chapter 21

... – To treat genital warts caused by the herpes virus ...
The Immune System - Life Sciences Outreach Program
The Immune System - Life Sciences Outreach Program

...  is broken into non-infective pieces  & attached to the cell’s MHC when processed through the cell’s machinery  MHC-antigen complex is placed on the cell membrane surface  where it is recognized by the T Helper cell ...
Innate Immunity and Antigen Presentation
Innate Immunity and Antigen Presentation

DISEASE - IMMUNE SYSTEM
DISEASE - IMMUNE SYSTEM

... and foreign substances (non-self). • Any foreign substance that triggers a specific defense response is called an antigen. ...
Document
Document

... – disease causing agents – produce infections  2 Lines of defense  Pathogens ...
Powerpoint Infectious Diseases
Powerpoint Infectious Diseases

... Highly adapted mosquito-borne protozoan; derived from gorilla ancestor; RBCs (no MHC); dangerous forms adhere to blood vessels in the microvasculature of peripheral organs to escape removal by spleen macrophages ...
Recombinant Human GM-CSF
Recombinant Human GM-CSF

... GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in respons ...
lecture_27_Mar_19_invert_immunity
lecture_27_Mar_19_invert_immunity

... microbes and prevent infection. Unlike adaptive immunity, innate immunity does not recognize every possible antigen. Instead, it is designed to recognize a few highly conserved structures present in many different microorganisms. The structures recognized are called pathogen-associated molecular pat ...
White Blood Cells
White Blood Cells

... 6 hours–few days fine, faintly pink (days in spleen ...
AP Bio - Semester 2 Review
AP Bio - Semester 2 Review

... VIII. Major Histocompatibility Complexes (MHC’s) – These membrane proteins are “special hands” on regular cells and WBCs. A. Two types exist: 1. Class I – All cells other than WBC’s possesses these. These are for telling WBC’s that a cell is infected when they are put out on the surface holding an a ...
PowerPoint Presentation - New Life College of Nursing
PowerPoint Presentation - New Life College of Nursing

... Blood and interstitial fluids contains three main types of antimicrobial proteins that discourage microbial growth. ...
Immunity Answers
Immunity Answers

... What is meant by “herd immunity”?  Herd immunity occurs when a large number of people are vaccinated at the same time. This prevents the pathogen from being transmitted within the population because there are no longer any host individuals who act as reservoirs of infection. ...
Mechanism of delayed hypersensitivity
Mechanism of delayed hypersensitivity

... • ACAID is initiated by an antigen-specific signal generated within the anterior chamber via intraocular dendritic cells and macrophages. • Under the influence of immunoregulatory factors (____________________________________) in aqueous humor, these cells: – capture antigen – process it uniquely – ...
Chapter 18: Blood
Chapter 18: Blood

...  large, abundant, violet granules (obscure a large S-shaped nucleus) ...
a13 Innate Immunity
a13 Innate Immunity

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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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