Lecture 4 Antigen Recognition
... Pre-existence of of many different potential antibody producing cells Each cell displays surface receptors for specific antigens Antigen encounter selects cells ...
... Pre-existence of of many different potential antibody producing cells Each cell displays surface receptors for specific antigens Antigen encounter selects cells ...
Hematopoiesis, immunity, hypoproliferative anemias
... proteins called growth factors; as they mature they lose the ability to divide Mature neutrophils and red cells enter the blood Megakaryocytes break into small fragments (platelets), which enter blood ...
... proteins called growth factors; as they mature they lose the ability to divide Mature neutrophils and red cells enter the blood Megakaryocytes break into small fragments (platelets), which enter blood ...
Physiology Lecture 10
... Hematopoiesis is the formation of blood cells. The liver is the major hematopoietic organ of the fetus, but then the stem cells migrate to the bone marrow. The hematopoietic stem cells form a population of relatively undifferentiated, multi-potent stem cells that give rise to all of the specialized ...
... Hematopoiesis is the formation of blood cells. The liver is the major hematopoietic organ of the fetus, but then the stem cells migrate to the bone marrow. The hematopoietic stem cells form a population of relatively undifferentiated, multi-potent stem cells that give rise to all of the specialized ...
ppt
... If external defenses are not effective – nonspecific, innate response Local inflammatory response – injury or pathogens can cause mast cells of connective tissues to release histamine, triggering dilation and increased permeability of capillaries Fever – systemic (widespread) response that increase ...
... If external defenses are not effective – nonspecific, innate response Local inflammatory response – injury or pathogens can cause mast cells of connective tissues to release histamine, triggering dilation and increased permeability of capillaries Fever – systemic (widespread) response that increase ...
Vitamin A Quercetin Vitamin C Goldenseal Echinacea Ginseng Did
... with a principal effect being a decrease in the pathogen-specific response.12 ...
... with a principal effect being a decrease in the pathogen-specific response.12 ...
File
... Explain the importance of phagocytosis, natural killer cells, and fever in innate body defense. • Phagocytes: white blood cells that ingest and digest (eat) foreign invaders • Neutrophils: most abundant phagocytes, but die fighting; become phagocytic on exposure to infectious material • Macrophage ...
... Explain the importance of phagocytosis, natural killer cells, and fever in innate body defense. • Phagocytes: white blood cells that ingest and digest (eat) foreign invaders • Neutrophils: most abundant phagocytes, but die fighting; become phagocytic on exposure to infectious material • Macrophage ...
Medical Terminology Chapter 3: Bacteria, Blood cells and Diseases
... (eat or engulf/swallowing) foreign cells, bacteria, and viruses. • When taking a Differential WBC Count of normal blood, this type of cell would be the most numerous. Normally, neutrophils account for approx 60% of all leukocytes. If the count exceeds this amount, the cause is usually due to infecti ...
... (eat or engulf/swallowing) foreign cells, bacteria, and viruses. • When taking a Differential WBC Count of normal blood, this type of cell would be the most numerous. Normally, neutrophils account for approx 60% of all leukocytes. If the count exceeds this amount, the cause is usually due to infecti ...
Administrative Office St. Joseph`s Hospital Site, L301
... A phase I gene therapy study in patients with metastatic melanoma has been recently completed. This work highlights a new type of cell known as a Dendritic Cell (DC). DCs are a heterogeneous population of antigen presenting cells (APCs) identified in various tissues including the skin (Langerhans ce ...
... A phase I gene therapy study in patients with metastatic melanoma has been recently completed. This work highlights a new type of cell known as a Dendritic Cell (DC). DCs are a heterogeneous population of antigen presenting cells (APCs) identified in various tissues including the skin (Langerhans ce ...
The Teaching of Immunology Using Educational Gaming Paradigms
... The immune system includes many interdependent systems of the body, which act to stop invasions by pathogens. Pathogens are any object that causes disease and include bacteria and viruses. When a pathogen enters the bloodstream either through a cut or the mucous membranes in the nose and mouth, it i ...
... The immune system includes many interdependent systems of the body, which act to stop invasions by pathogens. Pathogens are any object that causes disease and include bacteria and viruses. When a pathogen enters the bloodstream either through a cut or the mucous membranes in the nose and mouth, it i ...
Human Physiology - Daniela Sartori
... Provide first line of cell-mediated defense Considered to be part of the innate immune system Possess an array of surface receptors that allow them to fight viruses, bacteria, parasites ...
... Provide first line of cell-mediated defense Considered to be part of the innate immune system Possess an array of surface receptors that allow them to fight viruses, bacteria, parasites ...
39. Immune system
... off of mucus membranes. • Cilia in the respiratory tract move mucus out of the lungs to keep bacteria and viruses out. ...
... off of mucus membranes. • Cilia in the respiratory tract move mucus out of the lungs to keep bacteria and viruses out. ...
ImmunThe(NoTP)
... within 15 months of diagnosis -- showed that the vaccine safely increased average survival to nearly 48 weeks, compared with about 33 weeks among patients who didn't receive the treatment. The sixmonth survival rate was 93 percent for the vaccinated group, compared with 68 percent for 86 other gliob ...
... within 15 months of diagnosis -- showed that the vaccine safely increased average survival to nearly 48 weeks, compared with about 33 weeks among patients who didn't receive the treatment. The sixmonth survival rate was 93 percent for the vaccinated group, compared with 68 percent for 86 other gliob ...
Central nervous system control and coordination
... membrane of cells. It is most effective in removing virus-infected cells, but it also assists B cells in defending against fungi, intracellular bacteria and protozoan. Cellular immunity protects the body by causing activation of antigenspecific cytotoxic T cells which destroy body cells displaying e ...
... membrane of cells. It is most effective in removing virus-infected cells, but it also assists B cells in defending against fungi, intracellular bacteria and protozoan. Cellular immunity protects the body by causing activation of antigenspecific cytotoxic T cells which destroy body cells displaying e ...
Thymus gland Bone marrow Secondary organs of immune system
... •They also reduce risk of death if immune system is unsuccessful. ...
... •They also reduce risk of death if immune system is unsuccessful. ...
Immunoglobulins
... - The IgG isotype, except for IgG2, is the only isotype that can pass through the placenta as of the 3rd to 4th month of gestation - Passage is mediated by the FC portion - Role in health and disease ...
... - The IgG isotype, except for IgG2, is the only isotype that can pass through the placenta as of the 3rd to 4th month of gestation - Passage is mediated by the FC portion - Role in health and disease ...
The role of IL-12/IL-23 in Crohn`s disease
... be activated; however, these short-term inflammatory processes may not be enough to deal with the invasion and the adaptive immune response will then become activated. This may result in acute intestinal inflammation which can usually be resolved by the suppression of these pro-inflammatory immune r ...
... be activated; however, these short-term inflammatory processes may not be enough to deal with the invasion and the adaptive immune response will then become activated. This may result in acute intestinal inflammation which can usually be resolved by the suppression of these pro-inflammatory immune r ...
Mucosal Immunisation (Lung and Middle Ear)
... Upper and lower respiratory epithelium Ciliated Mucocillary clearance: ~1010 particles per day Alveolar Macrophages Poor APC but excellent “cleaners” without initiating inflammation Neutrophils Excellent “cleaners” but cause significant collateral damage ...
... Upper and lower respiratory epithelium Ciliated Mucocillary clearance: ~1010 particles per day Alveolar Macrophages Poor APC but excellent “cleaners” without initiating inflammation Neutrophils Excellent “cleaners” but cause significant collateral damage ...
3. Immunology
... Tissue macrophages also posses cell surface proteins of the major histocompatibility complex (MHC) which is important in transplantation immunity and presentation of antigen to helper T lymphocytes. ...
... Tissue macrophages also posses cell surface proteins of the major histocompatibility complex (MHC) which is important in transplantation immunity and presentation of antigen to helper T lymphocytes. ...
投影片 1
... Su CC, et al. 2007 Phosphatidylinositol 3-Kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells. J Immunol 179:4589-4597. ...
... Su CC, et al. 2007 Phosphatidylinositol 3-Kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells. J Immunol 179:4589-4597. ...
Alma Zernecke - Rudolf-Virchow
... of atherosclerosis, and convey paracrine alarm signals to recipient vascular cells, inducing CXCL12 expression. This is mediated by microRNA-126, enriched in apoptotic bodies, repressing the negative regulator of G-protein signaling, RGS16, and unlocking CXCR4 to trigger an auto-regulatory feedback ...
... of atherosclerosis, and convey paracrine alarm signals to recipient vascular cells, inducing CXCL12 expression. This is mediated by microRNA-126, enriched in apoptotic bodies, repressing the negative regulator of G-protein signaling, RGS16, and unlocking CXCR4 to trigger an auto-regulatory feedback ...
Canine Herpesvirus-1: A New Pathogenic Role for an Old Virus
... of malnutrition on the immune system. While malnutrition still remains a worldwide problem, lifestate [neonate or old age] and natural stress are increasingly becoming the major causes of lowered immune status in both humans and animals. Unlike immunodeficiency caused by malnutrition, lifestage and ...
... of malnutrition on the immune system. While malnutrition still remains a worldwide problem, lifestate [neonate or old age] and natural stress are increasingly becoming the major causes of lowered immune status in both humans and animals. Unlike immunodeficiency caused by malnutrition, lifestage and ...
Innate immune system
The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑