Immunogenic Consensus Sequence T Helper Epitopes for a Pan
... cystic fibrosis patients. Since BPM, BM and BC are all intracellular bacteria, they are excellent targets for T cell-based vaccines. However, the sheer volume of available genomic data requires the aid of immunoinformatics for vaccine design. Using EpiMatrix, ClustiMer and EpiAssembler, a set of imm ...
... cystic fibrosis patients. Since BPM, BM and BC are all intracellular bacteria, they are excellent targets for T cell-based vaccines. However, the sheer volume of available genomic data requires the aid of immunoinformatics for vaccine design. Using EpiMatrix, ClustiMer and EpiAssembler, a set of imm ...
Imd Signaling Pathway Drosophila The
... lack an adaptive immune system in the classical sense, it has long been recognized that they too possess powerful means of fighting infections, such as the ability to phagocytose bacteria and encapsulate parasites. In addition, insects can mount a humoral response against intruders. This is characte ...
... lack an adaptive immune system in the classical sense, it has long been recognized that they too possess powerful means of fighting infections, such as the ability to phagocytose bacteria and encapsulate parasites. In addition, insects can mount a humoral response against intruders. This is characte ...
Trichuris suis ova: Testing a helminth
... Through evolution, the immune system has developed from being composed only of cells of the innate immune system to acquiring the complex components of the acquired immune system. This evolution has taken place in response to the presence of various microorganisms, among which are helminths. The ide ...
... Through evolution, the immune system has developed from being composed only of cells of the innate immune system to acquiring the complex components of the acquired immune system. This evolution has taken place in response to the presence of various microorganisms, among which are helminths. The ide ...
Macrophage polarization in metabolic disorders - HAL
... simplifies the in vivo situation where the full phenotypic spectrum between M1 and M2 can exist [8]. Moreover, an alternative classification of macrophage populations has been proposed based on three different macrophage homeostatic activities: host defence, wound healing and immune regulation [8]. ...
... simplifies the in vivo situation where the full phenotypic spectrum between M1 and M2 can exist [8]. Moreover, an alternative classification of macrophage populations has been proposed based on three different macrophage homeostatic activities: host defence, wound healing and immune regulation [8]. ...
An Introduction to Artificial Immune Systems
... determine its stimulation level (based on antigenic and network interaction) 2.2 Metadynamics: eliminate network cells with a low stimulation 2.3 Clonal Expansion: select the most stimulated network cells and reproduce them proportionally to their stimulation 2.4 Somatic hypermutation: mutate each c ...
... determine its stimulation level (based on antigenic and network interaction) 2.2 Metadynamics: eliminate network cells with a low stimulation 2.3 Clonal Expansion: select the most stimulated network cells and reproduce them proportionally to their stimulation 2.4 Somatic hypermutation: mutate each c ...
Plasma Membrane Profiling Defines an Expanded Class of
... HCMV is the prototype betaherpesvirus and an important human pathogen. Following primary infection, HCMV persists for the lifetime of the host under constant control by the host immune system. In the face of this selective pressure, HCMV has evolved multiple mechanisms to evade immune detection and ...
... HCMV is the prototype betaherpesvirus and an important human pathogen. Following primary infection, HCMV persists for the lifetime of the host under constant control by the host immune system. In the face of this selective pressure, HCMV has evolved multiple mechanisms to evade immune detection and ...
Endometrial dendritic cell populations during the normal menstrual
... focused on DCs in the decidualized endometrium and their possible role in early spontaneous abortion (Kammerer et al., 2000; Gardner and Moffett, 2003; Askelund et al., 2004). DCs are crucial mediators of the immune response and tolerance, and are likely to be involved in this balance between immune ...
... focused on DCs in the decidualized endometrium and their possible role in early spontaneous abortion (Kammerer et al., 2000; Gardner and Moffett, 2003; Askelund et al., 2004). DCs are crucial mediators of the immune response and tolerance, and are likely to be involved in this balance between immune ...
toxic plant booklet
... sumac. All three species contain the toxic oil urushiol, which can cause an allergic reaction in sensitive individuals following exposure (Sachs, 2001). Urushiol resins are highly stable and remain viabl ...
... sumac. All three species contain the toxic oil urushiol, which can cause an allergic reaction in sensitive individuals following exposure (Sachs, 2001). Urushiol resins are highly stable and remain viabl ...
PDF - Oxford Academic - Oxford University Press
... reveals a shared U-box domain (amino acids 300–363 in StPUB17), and three ARM repeat domains (amino acids 430–470, 515–555, 556–594 in StPUB17) in the C-terminal halves of the proteins (see Supplementary Fig. S1 at JXB online). To test whether StPUB17 possesses E3 ubiquitin ligase activity, full-len ...
... reveals a shared U-box domain (amino acids 300–363 in StPUB17), and three ARM repeat domains (amino acids 430–470, 515–555, 556–594 in StPUB17) in the C-terminal halves of the proteins (see Supplementary Fig. S1 at JXB online). To test whether StPUB17 possesses E3 ubiquitin ligase activity, full-len ...
PDF - Journal of Veterinary Science
... using OMP and DNT of B. bronchiseptica as antigens. Generally, antibody titers peaked at 4 and 6 weeks in sera and egg yolks, respectively, after the first injection (Fig. 1 and 2). The titers of the vaccinated groups were three times higher than those of the control group. Antibody profiles against ...
... using OMP and DNT of B. bronchiseptica as antigens. Generally, antibody titers peaked at 4 and 6 weeks in sera and egg yolks, respectively, after the first injection (Fig. 1 and 2). The titers of the vaccinated groups were three times higher than those of the control group. Antibody profiles against ...
A Diagnostic Target Against Clostridium bolteae
... experience that you shared with me was not taken for granted. You provided all of the support and help necessary to keep me working towards my goal and completing my project. I have learned a lot working in your lab and realized my unwavering passion for research. Thank you for all that you have don ...
... experience that you shared with me was not taken for granted. You provided all of the support and help necessary to keep me working towards my goal and completing my project. I have learned a lot working in your lab and realized my unwavering passion for research. Thank you for all that you have don ...
CARBON NANOTUBES AS CARRIERS FOR DELIVERY OF BIOACTIVE AND THERAPEUTIC AGENTS: AN OVERVIEW Review Article
... some organic groups to the sidewalls and/or tips of the CNTs. Briefly, purified SWNTs and aniline are mixed together. Under the pressure from the mixing force, the outermost nanotubes from the bundle is librated and is exposed to the reactive agent. Thus, th ...
... some organic groups to the sidewalls and/or tips of the CNTs. Briefly, purified SWNTs and aniline are mixed together. Under the pressure from the mixing force, the outermost nanotubes from the bundle is librated and is exposed to the reactive agent. Thus, th ...
(2016) Innate Immunity and Asthma Risk in Amish and Hutterite
... Figure 2. Proportions of Peripheral-Blood Leukocytes and Cell-Surface–Marker Phenotypes in Amish and Hutterite Children. The percentages of total peripheral-blood leukocytes (Panel A) were determined with flow cytometry for neutrophils (defined as CD66b+Siglec-8+), eosinophils (defined as CCR3+Sigle ...
... Figure 2. Proportions of Peripheral-Blood Leukocytes and Cell-Surface–Marker Phenotypes in Amish and Hutterite Children. The percentages of total peripheral-blood leukocytes (Panel A) were determined with flow cytometry for neutrophils (defined as CD66b+Siglec-8+), eosinophils (defined as CCR3+Sigle ...
Nature of Immunity - Napa Valley College
... erythematosus) erythematosus) Attacks foreign tissue (organ transplant rejection or transfusion reaction) ...
... erythematosus) erythematosus) Attacks foreign tissue (organ transplant rejection or transfusion reaction) ...
Signal transducer and activator of transcription 2
... See Dasgupta et al. (doi:10.1093/awv237) for a scientific commentary on this article. Defects of mitochondrial dynamics are emerging causes of neurological disease. In two children presenting with severe neurological deterioration following viral infection we identified a novel homozygous STAT2 mutati ...
... See Dasgupta et al. (doi:10.1093/awv237) for a scientific commentary on this article. Defects of mitochondrial dynamics are emerging causes of neurological disease. In two children presenting with severe neurological deterioration following viral infection we identified a novel homozygous STAT2 mutati ...
Non-small-cell lung cancers: a heterogeneous set of diseases
... including the discovery of recurrent aberrations such as the ROS1 fusions and the potential diagnostic or prognostic marker isocitrate dehydrogenase 1 (IDH1)17,33,34. Such advances in high-throughput technology are promoting rapid advances in our understanding of NSCLC biology and, ultimately, will ...
... including the discovery of recurrent aberrations such as the ROS1 fusions and the potential diagnostic or prognostic marker isocitrate dehydrogenase 1 (IDH1)17,33,34. Such advances in high-throughput technology are promoting rapid advances in our understanding of NSCLC biology and, ultimately, will ...
Fatty acids and lymphocyte functions
... greatly in excess of those which can be attained in vivo. The effects of changing the amounts or types of fat in the diet on lymphocyte functions can be studied by isolating lymphocytes from animals or humans which have undergone dietary changes and culturing them ex vivo. While this has some of the ...
... greatly in excess of those which can be attained in vivo. The effects of changing the amounts or types of fat in the diet on lymphocyte functions can be studied by isolating lymphocytes from animals or humans which have undergone dietary changes and culturing them ex vivo. While this has some of the ...
as Adobe PDF - Edinburgh Research Explorer
... most abundant and diverse natural biopolymers, composed of saccharides that are typically added to nascent proteins and lipids within the cell secretory pathway (endoplasmatic reticulum and Golgi apparatus). The glycome represents the entire glycan repertoire of an organism/ tissue/cell/protein, and ...
... most abundant and diverse natural biopolymers, composed of saccharides that are typically added to nascent proteins and lipids within the cell secretory pathway (endoplasmatic reticulum and Golgi apparatus). The glycome represents the entire glycan repertoire of an organism/ tissue/cell/protein, and ...
Janeway`s Immunology - Cal State LA
... • T helper cells recognize peptide on MHC II and utilize CD4 to ensure proper binding to MHC II. • CTL recognize peptide on MHC I and utilize CD8 to ensure proper binding to MHC I. ...
... • T helper cells recognize peptide on MHC II and utilize CD4 to ensure proper binding to MHC II. • CTL recognize peptide on MHC I and utilize CD8 to ensure proper binding to MHC I. ...
Innate immune system
The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑