11050-HNAC - Sino Biological Inc.
... complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF, was demonstrated to exhibits the growth stimulating activity of NGF. β-NGF is a target-derived secreted homodimeric protein of two 120-amino acid mature polypeptides after proteolytic r ...
... complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF, was demonstrated to exhibits the growth stimulating activity of NGF. β-NGF is a target-derived secreted homodimeric protein of two 120-amino acid mature polypeptides after proteolytic r ...
Chapter 15 / Lecture Outline 36
... 1. The presence of lactose induces expression of the genes required for lactose utilization 2. Analysis of the lactose induction system was a wise choice for the study of gene regulation B. Experiments analyzing the behavior of lactose-utilization mutants reveal the coordinate repression and inducti ...
... 1. The presence of lactose induces expression of the genes required for lactose utilization 2. Analysis of the lactose induction system was a wise choice for the study of gene regulation B. Experiments analyzing the behavior of lactose-utilization mutants reveal the coordinate repression and inducti ...
C H E M I S T R Y
... • used to treat a disease that is caused by a gene that fails to produce a necessary protein or that produces a dysfunctional protein ...
... • used to treat a disease that is caused by a gene that fails to produce a necessary protein or that produces a dysfunctional protein ...
Final Exam Study Guide Ms. Thomas Spring 2011
... 16. Draw the following cycles and define each process within the cycle: a. Water b. Carbon c. Nitrogen 17. How many chromosomes are present in a human sex cell? 18. How much energy is transferred from one trophic level to the next? 19. List the differences between mitosis and meiosis. 20. List the t ...
... 16. Draw the following cycles and define each process within the cycle: a. Water b. Carbon c. Nitrogen 17. How many chromosomes are present in a human sex cell? 18. How much energy is transferred from one trophic level to the next? 19. List the differences between mitosis and meiosis. 20. List the t ...
Gene-order Comparisons
... Use this matrix to cluster the sequence by a neighbor-joining algorithm (the same procedure as that used to make a phylogenetic tree) Cluster representation: Tree or Dendrogram As smaller groups are chosen, the most strongly supported clusters are more likely to be made up of paralogs(?) ...
... Use this matrix to cluster the sequence by a neighbor-joining algorithm (the same procedure as that used to make a phylogenetic tree) Cluster representation: Tree or Dendrogram As smaller groups are chosen, the most strongly supported clusters are more likely to be made up of paralogs(?) ...
Assorted Multiple Choice - mvhs
... 6. One trait in ivy plants is the presence of spots. The purple spotted allele (h) is recessive while the gold spotted allele (H) is dominant. The ability to show spots is controlled by another gene—M. Only ivy plants with an M allele will be able to show their spots. Otherwise, they will show no sp ...
... 6. One trait in ivy plants is the presence of spots. The purple spotted allele (h) is recessive while the gold spotted allele (H) is dominant. The ability to show spots is controlled by another gene—M. Only ivy plants with an M allele will be able to show their spots. Otherwise, they will show no sp ...
pathologic-cplxs+operons - Bioinformatics Research Group at
... Compute log likelihood of two genes being WO or TUB pair based on intergenic distance. ...
... Compute log likelihood of two genes being WO or TUB pair based on intergenic distance. ...
Symmetry in Protein Structures
... one could possibly imagine such as collecting sun light, transporting materials, provide mechanical strength or even fighting with viruses or bacteria etc. Yet proteins are relatively simple molecules. A protein (or a subunit) consists of a number of amino acids (there are 20 types of them) connecte ...
... one could possibly imagine such as collecting sun light, transporting materials, provide mechanical strength or even fighting with viruses or bacteria etc. Yet proteins are relatively simple molecules. A protein (or a subunit) consists of a number of amino acids (there are 20 types of them) connecte ...
Macromolecules Worksheet #2
... molecules. The sequence of amino acids in each protein is unique to that protein, so each protein has its own ...
... molecules. The sequence of amino acids in each protein is unique to that protein, so each protein has its own ...
Molecules of Life
... The building materials of the body are known as macromolecules because they can be very large ...
... The building materials of the body are known as macromolecules because they can be very large ...
WHAT IS PROTEIN?
... the essential amino acids our bodies cannot make and are therefore vital in our diets in small amounts. By contrast, incomplete proteins, which come from mainly plant sources, can be combined to make a complete protein. WHY IS PROTEIN IMPORTANT IN YOUR DIET? Protein makes up the largest percentage o ...
... the essential amino acids our bodies cannot make and are therefore vital in our diets in small amounts. By contrast, incomplete proteins, which come from mainly plant sources, can be combined to make a complete protein. WHY IS PROTEIN IMPORTANT IN YOUR DIET? Protein makes up the largest percentage o ...
Gene Section THRAP3 (thyroid hormone receptor associated protein 3)
... TRAP150 and its analog BCLAF1 are associated with SNIP1 (Smad nuclear interacting protein 1), pinin and SkIP (Ski-interacting protein) to form the SNIP1/SkIPassociated RNA processing (SNARP) complex. The SNARP regulates the expression level of cyclin D1 probably by recruiting U2AF65 to its pre-mRNA ...
... TRAP150 and its analog BCLAF1 are associated with SNIP1 (Smad nuclear interacting protein 1), pinin and SkIP (Ski-interacting protein) to form the SNIP1/SkIPassociated RNA processing (SNARP) complex. The SNARP regulates the expression level of cyclin D1 probably by recruiting U2AF65 to its pre-mRNA ...
Organic Compounds
... • Long chains of carbon atoms with attached hydrogen atoms (hydrocarbons) • Saturated fats contain only single bonds between the carbon atoms. • Unsaturated fats contain one or more double or triple bonds between the carbon ...
... • Long chains of carbon atoms with attached hydrogen atoms (hydrocarbons) • Saturated fats contain only single bonds between the carbon atoms. • Unsaturated fats contain one or more double or triple bonds between the carbon ...
Nucleic Acids - Spring Branch ISD
... 1. Enzymes denature. That means they change in shape by breaking 3o bonds. This can happen due to temperature or pH change. It is irreversible. 2. Competitive inhibitors: another chemical blocks the active site. May be unusable. ...
... 1. Enzymes denature. That means they change in shape by breaking 3o bonds. This can happen due to temperature or pH change. It is irreversible. 2. Competitive inhibitors: another chemical blocks the active site. May be unusable. ...
Prokaryotic Cells, Eukaryotic cells and HIV: Structures, Transcription
... nascent polypeptide can go into the ER, even if the protein is not finished being made. Water soluble and transmembrane proteins can be made in the ER. However, once proteins go in the ER they typically do NOT go back out into the cytosol. They can be put in the plasma membrane or another compartmen ...
... nascent polypeptide can go into the ER, even if the protein is not finished being made. Water soluble and transmembrane proteins can be made in the ER. However, once proteins go in the ER they typically do NOT go back out into the cytosol. They can be put in the plasma membrane or another compartmen ...
class notes
... p53 protein. The expression of several target genes is then activated by binding of the activated p53 to their regulatory regions. These genes are involved in processes that slow down the development of tumors. For example, some genes inhibit cell-cycle progression or the development of blood vessel ...
... p53 protein. The expression of several target genes is then activated by binding of the activated p53 to their regulatory regions. These genes are involved in processes that slow down the development of tumors. For example, some genes inhibit cell-cycle progression or the development of blood vessel ...
Composition of splicing complex in chloroplasts identified
... chloroplasts identified for the first time 2 July 2013, by Dr. Julia Weiler From gene to protein – craftwork required Genes, the bearers of genetic information, contain coding and non-coding regions. To convert a gene into a protein, enzymes first create a copy of the gene, the messenger RNA. A usef ...
... chloroplasts identified for the first time 2 July 2013, by Dr. Julia Weiler From gene to protein – craftwork required Genes, the bearers of genetic information, contain coding and non-coding regions. To convert a gene into a protein, enzymes first create a copy of the gene, the messenger RNA. A usef ...
Abstract Document Sample - graduate school of biostudies, kyoto
... FD, a bZIP transcription factor, preferentially expressed in the shoot apical meristem is required for FT protein to promote flowering. FD and FT proteins interact and act as a complex at the shoot apical meristem (SAM) to promote flowering. FD contains a possible phosphorylation sequence in its C-t ...
... FD, a bZIP transcription factor, preferentially expressed in the shoot apical meristem is required for FT protein to promote flowering. FD and FT proteins interact and act as a complex at the shoot apical meristem (SAM) to promote flowering. FD contains a possible phosphorylation sequence in its C-t ...
A proteomic platform that can also detect SNPs
... the SOMAscan assay can be utilized to not only detect protein levels, but, in some cases, identify individuals expressing alternate forms of proteins. The SOMAscan assay measures over 1000 human proteins in biological samples. For some analytes, the SOMamer reagents are sensitive to protein changes ...
... the SOMAscan assay can be utilized to not only detect protein levels, but, in some cases, identify individuals expressing alternate forms of proteins. The SOMAscan assay measures over 1000 human proteins in biological samples. For some analytes, the SOMamer reagents are sensitive to protein changes ...
Document
... CMT can generally be classified to demyelinating (CMT1 and 4) and axonal (CMT2) . HNPP is hereditary liability to multiple compression neuropathies with a demyeinating neuropathy. Demyelinating HN result from a variety of mutations in gene encoding proteins related to myelin structure and function ( ...
... CMT can generally be classified to demyelinating (CMT1 and 4) and axonal (CMT2) . HNPP is hereditary liability to multiple compression neuropathies with a demyeinating neuropathy. Demyelinating HN result from a variety of mutations in gene encoding proteins related to myelin structure and function ( ...
Creation of the largest human-designed protein boosts
... Because they have two identical halves, dimers have a large degree of symmetry. By taking these symmetries into account, the Vanderbilt group was able to substantially reduce the amount of computing time required to create the FLR protein. Using 400 processors of the supercomputer at Vanderbilt’s Ad ...
... Because they have two identical halves, dimers have a large degree of symmetry. By taking these symmetries into account, the Vanderbilt group was able to substantially reduce the amount of computing time required to create the FLR protein. Using 400 processors of the supercomputer at Vanderbilt’s Ad ...
Chapter Five
... C. Denaturation of Proteins First step in its destruction Excess heat, alcohol, acids or salts of heavy metals can damage the body’s proteins Stomach acid opens up the protein’s structure and permits digestive enzymes to act upon the protein. ...
... C. Denaturation of Proteins First step in its destruction Excess heat, alcohol, acids or salts of heavy metals can damage the body’s proteins Stomach acid opens up the protein’s structure and permits digestive enzymes to act upon the protein. ...
Structure and Function of Macromolecules
... This 3-D model shows the enzyme integrase which is responsible for inserting HIV into the DNA of humans ...
... This 3-D model shows the enzyme integrase which is responsible for inserting HIV into the DNA of humans ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.