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In vitro translation of archaeal natural mRNAs at high temperature
In vitro translation of archaeal natural mRNAs at high temperature

... Optimization of the ionic conditions is illustrated in Fig. 2. A relatively high concentration (at least 15 raM) of Mg 2+ ions was required for appreciable translational activity (left panel). Unexpectedly, the polyamine spermine, indispensable for poly(U) translation, had a strong inhibitory effect ...
Amino Acids in the Tagish Lake Meteorite
Amino Acids in the Tagish Lake Meteorite

... chondrite rich in primitive organic matter (Grady et al., 2002). The pristine nature of the first samples collected provides an opportunity to study astromaterials that have not been significantly affected by terrestrial contamination. We demonstrate that nearly all identified amino acids in all pri ...
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... IV. The Eukaryotic Problem of Telomere Replication RNA primer near end of the chromosome on lagging strand can’t be replaced with DNA since DNA polymerase must add to a primer sequence. Do chromosomes get shorter with each replication??? ...
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... Cellulose is a polymer of glucose monomers that has a straight, rigid structure ...
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... Many copies–some of these have mutations that allow replicase to work better yet. ...
A Purine-Pyrimidine Classification Scheme of the Genetic Code
A Purine-Pyrimidine Classification Scheme of the Genetic Code

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Unit 1 – Human Cells Key Areas 1
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... A. Ribose sugar and guanine B. Ribose sugar and uracil C. Deoxyribose sugar and guanine D. Deoxyribose sugar and uracil ...
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... where the second and third phenylalanines may be replaced by a corresponding tryptophan, and tyrosine by phenylalanine or tryptophan. An enzyme system prepared from Bacillus brevis (ATCC 8185), active in tyrocidine biosynthesis, was resolved into three complementary fractions ...
Lecture 17/18 - Aerobic and Anaerobic Metabolism
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... All cells contain DNA; Would stop/inhibit DNA replication in normal cells; Stops/inhibits cell division; Named example on growth/repair e.g. no new blood cells made/no wound healing; ...
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... “special” information transfers • Reverse transcription (RNA  DNA): In retroviruses (HIV) and eukaryotes (retrotransposons and telomere synthesis). • RNA replication (RNA  RNA): Many viruses replicate by RNA-dependent RNA polymerases (also used in eukaryotes for RNA silencing). • Direct translati ...
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... Retrieval of Genetic Information: Central to any information storage system is the ability to access and retrieve the information and to convert it to a usable form. In addition to the sequence information that will be translated into protein via the triplet code, a gene also contains sequence info ...
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... "debranching enzyme" when glycogen is needed for energy. Although glycogen has some helix, it is more like amylopectin: it forms less inclusion compounds with iodine. The color obtained is amber red and may be stabilized with the addition of the dihydrate of calcium chloride. Each glycogen molecule ...
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... (PKU) are severe inborn errors of amino acid (AA) metabolism which, if left untreated, can have catastrophic consequences for the child. Maple Syrup Urine Disease results from a genetic defect of the branched-chain a-keto acid dehydrogenase enzyme system. This metabolic defect is characterized by an ...
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... specified by the genetic code and polymerized into proteins by ribosomal translation. All amino acids contain an a carbon to which typically 4 different substituent groups are attached (Fig. 3-2). These groups are the aamino group, the a-carboxyl group, hydrogen, and the variable R group (side-chain ...
Lecture DONE exam 1A MP
Lecture DONE exam 1A MP

... A) Golgi apparatus, rough ER, lysosome B) Lysosome, Golgi apparatus, plasma membrane C) Plasma membrane, vesicle, lysosome D) Rough ER, cytoplasm, plasma-membrane E) Rough ER, Golgi apparatus, vesicle, plasma-membrane 25. What is attached to the 5´-carbon of ribose in RNA? A) Adenine B) Ribose C) Ur ...
Central dogma of molecular biology
Central dogma of molecular biology

... factors and elongation factors bring aminoacylated transfer RNAs (tRNAs) into the ribosomemRNA complex, matching the codon in the mRNA to the anti-codon in the tRNA, thereby adding the correct amino acid in the sequence encoding the gene. As the amino acids are linked into the growing peptide chain, ...
Word Count: 1390 An experiment to determine the amount of urea in
Word Count: 1390 An experiment to determine the amount of urea in

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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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