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BCH 4024, Spring 2017 - Department of Biochemistry and Molecular
BCH 4024, Spring 2017 - Department of Biochemistry and Molecular

... WITH PRIOR PERMISSION from Dr. Cain. Generally, this will be illness, injury, or some other unforeseeable scheduling conflict. Written documentation will be required for all makeup requests. All make-up exams are scheduled for Thursday, April 6 at 8:30 AM. Be warned that previous history suggests mi ...
Bchm2000_P5 - U of L Class Index
Bchm2000_P5 - U of L Class Index

... (c) A disaccharide of two riboses connected by a (1-1) glycosidic bond. (d) A disaccharide building block of the polysaccharide amylose. (5) The transformed, standard free energy change for the formation of glucose-6phosphate from glucose and phosphate is +13.8 kJ/mol. Assuming T=37º C, are there ...
1 - Humble ISD
1 - Humble ISD

... 13. On a separate sheet of paper, outline condensation and hydrolysis in proteins, saccharides and triglycerides. Label the reactions and bonds formed/ broken clearly. 14. Triglycerides can have saturated or unsaturated fatty acids attached. Differentiate between saturated and unsaturated fats in te ...
Summary of glycolysis (Embden
Summary of glycolysis (Embden

Blackline Master 4.2-2 NAME: DATE: 4.2
Blackline Master 4.2-2 NAME: DATE: 4.2

... Complete the summaries below by filling in the blanks. 1. Pyruvate oxidation ________________ enters the mitochondrion from the cytoplasm. One ________________ atom is removed via ___________________, and ________________ is removed using ________. ________________ becomes attached to the remaining ...
Lecture 35 - Lipid Metabolism 1
Lecture 35 - Lipid Metabolism 1

... active conformation is dephosphorylated) and allosteric mechanisms (citrate binding stimulates activity, palmitoyl-CoA inhibits activity). ...
biomass composition
biomass composition

... (growth rate and limiting substrate). For example, as the growth rate increases the cellular content of RNA usually increases, while the protein and DNA content decreases (Novak, L. et al., 2000). The relative content of cell wall polymers also decreases with the increase of the growth rate (Benthin ...
Attenuation regulation of amino acid biosynthetic operons in
Attenuation regulation of amino acid biosynthetic operons in

... Fig. 2. Selected amino acid biosynthetic pathways of c- and a-proteobacteria. (A) ILV (isoleucine, leucine, and valine); (B) HIS (histidine); (C) THR (threonine); and (D) aromatic amino acids (tryptophan, tyrosine, and phenylalanine). ...
Structural and functional studies on C4b
Structural and functional studies on C4b

Enzymes: Principles of Catalysis
Enzymes: Principles of Catalysis

... In order to function properly, some enzymes require the presence of an additional chemical component such as inorganic ions (Zn2+ or Fe2+). These inorganic ions are known as for enzymes. ...
enzymes
enzymes

... reaction — the cleavage of a peptide chain, but they display very different specificities. •Trypsin cleaves peptides on the carbonyl side of the basic amino acids, arginine or lysine. •Chymotrypsin prefers to cleave on the carbonyl side of aromatic residues, such as phenylalanine and tyrosine. • Ela ...
PowerPoint 0.3MB - The Biomolecular Modeling & Computational
PowerPoint 0.3MB - The Biomolecular Modeling & Computational

... • BUT pattern have high preferences • A good predictor: The helical wheel – Helices are likely on outside of proteins – I, I+3 and I+4 hydrophobic interface ...


... 8. (10 pts) Please do one of the following three questions. Please indicate your choice when answering the question. Choice A: A glutamic acid residue must be deprotonated for a protein to have biological function. The pKa of this glutamic acid residue is 5.0. Draw a graph that shows the activity of ...
Lesson 3
Lesson 3

... sporulation by Streptomyces clavuligerus. • Spore storage, however, could be a problem, since the spores lost 72% of their viability after storage for 1 week in buffer at 4°C. • Many strains isolated from nature and often strains that have been subjected to a mutation program result in an “unstable” ...
In the light of the haloarchaea metabolism
In the light of the haloarchaea metabolism

... pathway where 2-oxoglutarate is synthesized from oxaloacetate, and the other uses an incomplete route where 2-oxoglutarate is formed via citrate. It is possible that the type of citric acid cycle present in an archaea will determine enzyme function and, hence, reflect any unique features. Isocitrate ...
1. Metabolic Synthesis - Princeton University Press
1. Metabolic Synthesis - Princeton University Press

Chap 4 Study Guide
Chap 4 Study Guide

... In a similar fashion, triglycerides and amino acids can be combusted in the cell, transferring energy to power the cell's many energy-requiring processes. Complete combustion of these fuels requires that we breathe so that blood can deliver the gas 66. ____________, which is the final electron 67. _ ...
What are enzymes and how do they work
What are enzymes and how do they work

... MODEL 2:You reheat the test tube from Q #8 to 95°C. Hydrogen bonds break and produce the four separated nucleic acid strands below: ...
9701/04 - StudyGuide.PK
9701/04 - StudyGuide.PK

... What starting material and reagent are needed to form this acyl chloride? ...
The Acid End-products of Glucose Metabolism of Oral
The Acid End-products of Glucose Metabolism of Oral

... The probable pathway in haemophili is carboxylation of phosphoenolpyruvate to oxalacetate by phosphoenolpyruvate-carboxylase,then via malate and fumarate to succinate catalysed by malate dehydrogenase, fumarase and succinic dehydrogenase, respectively. Acetate would presumably be formed from pyruvat ...
Metabolic diseases
Metabolic diseases

... deficiency, but is rare. It is inherited in a autosomal recessive pattern and is the commonest cause of the so-called "congenital nonspherocytic haemolytic anaemias" (CNSHA). PK catalyses the conversion of phosphoenolpyruvate to pyruvate with the generation of ATP. Inadequate ATP generation leads to ...
INDIGO-BINDING DOMAINS IN CELLULASE MOLECULES
INDIGO-BINDING DOMAINS IN CELLULASE MOLECULES

... sedimentation of gel particles, liquid above the gel was removed, gel was washed two times with 1.5 ml of water for 5 min on a magnetic stirrer, and then indigo incorporated into the gel was extracted with DMSO. Three extractions with 1 ml of DMSO for 10 min on a magnetic stirrer were carried out. T ...
biochemistry-part1
biochemistry-part1

Design and Operation of Large Scale RNA production v2
Design and Operation of Large Scale RNA production v2

... • Basic Synthetic Cycle Steps • The Detritylation Step (deblocking) • The Coupling (Activation) Step ...
protein_folding.ver9 - RI
protein_folding.ver9 - RI

... quaternary structure of proteins). Chemical Bonds allows students to make connections between the polar and non-polar nature of bonds and how one part of a molecule could be partially positive or negative due to the uneven sharing of electrons. The Solubility activity highlights the tendencies of gl ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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