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insulin resistance
insulin resistance

... while liver, muscles and fat require insulin for glucose uptake, blood vessels, nerves, kidney and the eye lens do not require insulin Thus, increased intracellular levels of glucose in these cells causes: •non-enzymatic glycation (glucose binds to proteins) = AGEs (advanced ...
Characterization of serine/threonine protein phosphatases in
Characterization of serine/threonine protein phosphatases in

... In the last decade, a great deal of interest has been focused on how reversible phosphorylation of proteins is involved in regulation of cellular functions [4-7, 20]. Reversible changes in levels of phosphoserine and phosphothreonine at specific residues are a means by which the activity of many key ...
Science 10 student notes
Science 10 student notes

... You are private detectives who have been hired to investigate the death of a wealthy but eccentric Mr. Xavier, a man who was well known for his riches and for his reclusive nature. He avoided being around others, because he was always filled with anxiety and startled easily. He also suffered from pa ...
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cell surface lipids and adhesion

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Cell - mrhubbardsci

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WSFNR-17-13 Coder - Warnell School of Forestry and Natural
WSFNR-17-13 Coder - Warnell School of Forestry and Natural

Scholarly Interest Report
Scholarly Interest Report

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March 1972 EFFECTS OF VOLATILE FA`M`Y ACIDS, KETONE
March 1972 EFFECTS OF VOLATILE FA`M`Y ACIDS, KETONE

... insulin is relatively low. Jungas and Ball [2 I] observed that lipolysis in rat fat pads became less sensitive to inhibition by insulin at a concentration of 1 mu/ml the same concentration that we used - when the concentration of adrenalin was increased. Kuo [23] observed the same for noradrenalin w ...
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The CoFactor database: organic cofactors in enzyme catalysis

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PROTEIN EXTRACTION AND PURIFICATION

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lecture 6 ppt

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Биохимия жидкостей полости рта

... of saliva • Saliva contains proteins, lipids, vitamins, hormones, organic acids, non-protein nitrogenous compounds - urea, uric acid, free amino acids and nucleic acids. • Organic substances of saliva can be divided into 2 groups: protein and non-protein nature. • Most salivary proteins are glycopro ...
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Analysis and simulation of metabolic networks: Application to HEPG2

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Nucleic Acids - notescentre.com
Nucleic Acids - notescentre.com

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Nucleic Acids

PENTOSE PHOSPHATE PATHWAY AND FRUCTOSE METABOLISM
PENTOSE PHOSPHATE PATHWAY AND FRUCTOSE METABOLISM

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How do bacteria respond to their environment?

... How does E. coli sense starvation for nitrogen? Is there a protein that binds ALL amino acids? ...
a new therapeutic lead to suppress hepatic glucose production
a new therapeutic lead to suppress hepatic glucose production

... So what are likely source(s) of increased PA levels in the absence of AGPAT enzymatic activity? The increased PA levels might be generated from alternate pathways such as Pld and/or Dagk (Figure 1G ) [8] . Although, from our studies, it is unclear which pathway is important for the generation of PA ...
Thoughts on Vitamin A, IBD and PSC
Thoughts on Vitamin A, IBD and PSC

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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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