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3-1 Cyclin-Dependent Kinases
3-1 Cyclin-Dependent Kinases

... interacts directly with cyclin and moves inward upon cyclin binding, causing the reorientation of residues that interact with the phosphates of ATP. The small L12 helix, just before the T-loop in the primary sequence, changes structure to become a beta strand upon cyclin binding, also contributing t ...
Chemistry
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... Copyright © 2004 Pearson Education, Inc. publishing as Benjamin Cummings ...
Metabolic Flux Analysis on the Production of Poly(3 - Wiley-VCH
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... eutropha was cultivated on a mixture of three carbon sources, lactate was consumed first as a large amount of ATP is needed for the transport of acetate and butyrate. The central metabolic pathways for the utilization of three carbon sources are very similar, except for the anaplerotic pathway which ...
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The Simplified Nitrogen Cycle
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... Keeping Ammonia Out. From the crystal structures and known features of the Amt and GlnK protein families, a mechanism was developed to explain regulation of ammonia uptake by a prokaryotic cell. One interesting aspect of the interactions between the two proteins is that an overall negative charge is ...
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Biology 103 Lecture and Biology 103A Lab Objectives
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... Note: oxygen is not used in the citric acid cycle 9. Trace the transfer of hydrogen or hydrogen electrons (from NADH2) through the electron transport system in aerobic cellular respiration. Know this is also called the cytochrome system. Include: role of NADH2, NAD+, cytochromes role of oxygen as th ...
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Chemical Reactions
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... substances are present, and then releases it, the protein immediately folds back to the same 3-D structure it had before. This folding process takes less than a second. Therefore, it seems that all the information necessary for the protein to achieve its “native structure” is contained in its amino ...
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... Results and Discussion Previously, we have reported on the ability of boronic acids to transport hydrophilic p-nitrophenyl β-D-glycosides through bulk, liquid membranes (BLMs).11,12 Depending on the experimental conditions, two transport pathways were found to operate. One pathway involved the forma ...
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... particle of matter. It translates to mean something that is indivisible. In the eighteenth century, chemist, John Dalton, revived the term when he suggested that each element was made up of unique atoms and the atoms of an element are all the same. At that time, there were about 35 known elements. T ...
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... Balance all atoms, except H and O Balance O by adding H2O to the opposite side of the equation Balance H by adding H+ (instead of cumbersome H3O+) to the appropriate side of the equation For acidic solutions, can have H+(aq), H2O(l), not OH(aq), never e(aq) or O2(aq); - for basic solutions can ha ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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