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Free Full Text ( Final Version , 339kb )
Free Full Text ( Final Version , 339kb )

... Both distributions have a Zipfian shape, which means that few SFs occur very frequently in MEDLINE, and many SFs occur rarely. There are 24,393 human genes in Locuslink, of which 12,533 (51.4%) have at least two symbols (or synonyms). 16,828 genes have a matching LF. Of these genes, 5,812 (34.5%) ha ...
Imprinting evolution and the price of silence
Imprinting evolution and the price of silence

... Other than typical sequence polymorphisms that do not correlate with imprint status, the nucleotide sequence of the two alleles of imprinted genes are identical. Therefore, the imprint marks that distinguish the two parental alleles must be epigenetic in nature. Epigenetic alterations are defined as ...
intelligence
intelligence

... (1) identical (monozygotic) twins, (2a) fraternal (dizygotic) twins, (2b) full siblings, (3) parent–offspring, and (4) half siblings. The intellectual similarity among these different types of familial relation can be determined by administering a test of intelligence to pairs of individuals from ma ...
Dosage Compensation Mechanisms: Evolution
Dosage Compensation Mechanisms: Evolution

... mechanisms able to equalize in both sexes the amount of products derived from sex-linked genes. Evolution of these mechanisms is understood in some detail in the fly Drosophila melanogaster, the nematode Caenorhabditis elegans and in eutherian mammals. ...
Sex chromosomes and gender
Sex chromosomes and gender

... Male-specific pressures on the Y chromosome caused a region that was spatially linked to Sry to diverge from the X chromosome, leading to a loss of homology and recombination of those portions of the two chromosomes. The loss of recombination was important because it led to progressive degeneration ...
Background and Overview of Comparative Genomics
Background and Overview of Comparative Genomics

... These genes have functions in basic metabolism or in determining specialized characteristics of the thousands of different cell types that make up the human body. The protein product of a gene may act as an enzyme (or an enzyme subunit), a transport molecule, a structural protein, a hormone, or a re ...
SEX CHROMOSOMES AND BRAIN GENDER
SEX CHROMOSOMES AND BRAIN GENDER

... Male-specific pressures on the Y chromosome caused a region that was spatially linked to Sry to diverge from the X chromosome, leading to a loss of homology and recombination of those portions of the two chromosomes. The loss of recombination was important because it led to progressive degeneration ...
Two genes from Bacillus subtilis under the sole control
Two genes from Bacillus subtilis under the sole control

Prof. Kamakaka`s Lecture 16 Notes
Prof. Kamakaka`s Lecture 16 Notes

... Catabolite Repression of the lac operonWhen we introduced the subject of regulation of gene expression, I gave an example of the response of E. coli when placed in a media containing both glucose and lactose. The induction of the lac operon does not occur until all the glucose has been metabolized. ...
sex chromosomes
sex chromosomes

... have coloration (dominant) or albinism/white (recessive). IF coloration is dominant, THEN a second gene will determine if the mouse will be brown or black. ...
Title: Genes in the Postgenomic Era Authors: Paul E. Griffiths and
Title: Genes in the Postgenomic Era Authors: Paul E. Griffiths and

... assumes that recombination - the association of alleles from two homologous chromosomes of a parent on a single chromosome in the offspring as a result of crossing over during meiosis - is a process that recombines whole genes. However, if recombination can occur within a gene, so that part of the g ...
Speaker: Dr. Arnob Dutta Title: Multiple mechanisms to regulate the
Speaker: Dr. Arnob Dutta Title: Multiple mechanisms to regulate the

... Title: Multiple mechanisms to regulate the Swi/Snf chromatin remodeler Abstract: The Swi/Snf chromatin remodeling complex functions to alter nucleosome positions by either sliding nucleosomes on DNA or the eviction of histones. The presence of histone acetylation and activator dependent recruitment ...
Temporal genomic evolution of bird sex chromosomes Open Access
Temporal genomic evolution of bird sex chromosomes Open Access

... and Z chromosomes. We focus all our analyses throughout this study between these two sets of chromosomes of a similar size, because microchromosomes have very different genomic features (i.e., recombination rate, gene density, GC content, repeat content etc.) compared to others [50], which influence ...
document
document

... Children with Galactosemia have lower (IQ) levels then their siblings ...
Article
Article

... targeted chromosomes (I and IX), the first candidate strains tested were correct, whereas for other targeted chromosomes, many strains had to be screened before one with the correct karyotype was identified. The number of strains that had to be screened before the correct karyotype was found is shown ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Molecular Identification of Specific Virulence Genes in EnteropathogenicEscherichia coli eae gene but did not possess thebfpAATT,bfpAAAT, eaf, stx1, stx2 and hlyA genes, these isolates identified as atypical EPEC. Fourty isolates (80%) of E. coli found do not have any one of the specific virulence ...
The amphioxus hairy family: differential fate after duplication.
The amphioxus hairy family: differential fate after duplication.

... and in somatic sex determination. In Tribolium, only a role during segmentation has been suggested for its single hairy gene. On the contrary, hairy genes are expressed in many places in vertebrate embryos and have been implicated in numerous functions, such as somitogenesis, neurogenesis, and endoc ...
Interplay between copy number, dosage compensation and
Interplay between copy number, dosage compensation and

... In contrast to work with single cell organisms, the impact of gene dosage on expression variability in metazoans is less well studied. However, a full understanding of the effect of gene copy deletions is fundamental for better understanding of diseases that originate from gene copy number changes. ...
(a) (b)
(a) (b)

alpha-thalassemia-pdf
alpha-thalassemia-pdf

... An individual with one abnormal alpha globin gene is said to be a silent carrier of alpha thalassemia. This condition, in which one of the four alpha globin genes is missing or defective, generally causes no health problems because the lack of alpha globin protein is so small that there is no anemia ...
Lecture9_10_extra2 - Welcome to people.pharmacy.purdue.edu!
Lecture9_10_extra2 - Welcome to people.pharmacy.purdue.edu!

Characterisation of the diol dehydratase pdu operon of Lactobacillus
Characterisation of the diol dehydratase pdu operon of Lactobacillus

... This result suggests that pduCDE are regulated via the 346-bp region upstream of pduA (Fig. 1B). Analysis of this region exhibited an average G+C of 30% in comparison to 45% normally found in the chromosome of L. collinoides. Three imperfect inverted repeats with the following consensus TTTtAAAnTAAT ...
GUEST COMMENTARY
GUEST COMMENTARY

... and lacY, must be relatively close to one another in the chromosome, and they must be transcribed from the same DNA strand. These requirements severely limited the general utility of the method, and it left many people thinking that fusions were very interesting but esoteric. In order to make geneti ...
Jeopardy - Spring2012edu625
Jeopardy - Spring2012edu625

... They are used to show all of the combinations of alleles that might result from a cross and the likelihood that each might occur. ...
Genome-wide histone modification patterns in
Genome-wide histone modification patterns in

< 1 ... 66 67 68 69 70 71 72 73 74 ... 401 >

Ridge (biology)

Ridges (regions of increased gene expression) are domains of the genome with a high gene expression; the opposite of ridges are antiridges. The term was first used by Caron et al. in 2001. Characteristics of ridges are:Gene denseContain many C and G nucleobasesGenes have short intronshigh SINE repeat densitylow LINE repeat density↑ 1.0 1.1
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