Gene targeting by hybridization-hydrolysis process
... A new technology used to specifically target any transcript from a complex population of single-strand cDNA molecules was applied to dramatically decrease the abundance of selected genes in cDNA libraries. This innovative procedure offers new alternatives to previous efforts focused on normalizing t ...
... A new technology used to specifically target any transcript from a complex population of single-strand cDNA molecules was applied to dramatically decrease the abundance of selected genes in cDNA libraries. This innovative procedure offers new alternatives to previous efforts focused on normalizing t ...
XSL Formatter - H:\XML
... instructions are provided for several common biological research problems that can be addressed by exploiting the whole-genome and positional perspectives of Map Viewer. Please be aware that the examples in these tutorials may return different results when you execute them, because the underlying da ...
... instructions are provided for several common biological research problems that can be addressed by exploiting the whole-genome and positional perspectives of Map Viewer. Please be aware that the examples in these tutorials may return different results when you execute them, because the underlying da ...
Gene Rearrangement Analysis and Ancestral Order Inference from
... Mutations in a genome consist of not only base pair level changes but also events that alter the chromosome structure, such as inversions, duplications or deletions [1]. Ancestral gene sequence inference has led to significant predictions of protein functional shift and positive selection [2]. For e ...
... Mutations in a genome consist of not only base pair level changes but also events that alter the chromosome structure, such as inversions, duplications or deletions [1]. Ancestral gene sequence inference has led to significant predictions of protein functional shift and positive selection [2]. For e ...
Prediction and Validation of Gene-Disease Associations
... phenotypes that share a higher than expected number of orthologous genes. In this way, a number of new, and often surprising, model systems were found for human diseases. For instance, the human neural crest related developmental disorder Waardenburg syndrome shares gene modules with gravitropism (t ...
... phenotypes that share a higher than expected number of orthologous genes. In this way, a number of new, and often surprising, model systems were found for human diseases. For instance, the human neural crest related developmental disorder Waardenburg syndrome shares gene modules with gravitropism (t ...
Bacterial physiological adaptations to contrasting edaphic
... Environmental factors relating to soil pH are widely known to be important in structuring soil bacterial communities, yet the relationship between taxonomic community composition and functional diversity remains to be determined. Here, we analyze geographically distributed soils spanning a wide pH g ...
... Environmental factors relating to soil pH are widely known to be important in structuring soil bacterial communities, yet the relationship between taxonomic community composition and functional diversity remains to be determined. Here, we analyze geographically distributed soils spanning a wide pH g ...
genstat - University of Illinois at Urbana
... http://www.bioalgorithms.info/slides.htm and Ying Xu’s lecture ...
... http://www.bioalgorithms.info/slides.htm and Ying Xu’s lecture ...
Codon usage in the Mycobacterium tuberculosis corn
... F,, is calculated as the number of occurrences of these 17 optimal codons, divided by the total number of occurrences of these 15 amino acids. The major trends in codon usage among genes were investigated using correspondence analysis (Greenacre, 1984). This is the most commonly used multivariate st ...
... F,, is calculated as the number of occurrences of these 17 optimal codons, divided by the total number of occurrences of these 15 amino acids. The major trends in codon usage among genes were investigated using correspondence analysis (Greenacre, 1984). This is the most commonly used multivariate st ...
toxicity in bread wheat - BMC Plant Biology
... and MATE1 were regulated by these transcription factors [18,19]. Recently, the contribution of ART1 locus to the variation for Al tolerance in rice has also been identified in QTL analysis [20]. The limited impact of single functional genes in plant stress tolerance has been associated with the poly ...
... and MATE1 were regulated by these transcription factors [18,19]. Recently, the contribution of ART1 locus to the variation for Al tolerance in rice has also been identified in QTL analysis [20]. The limited impact of single functional genes in plant stress tolerance has been associated with the poly ...
Oligogenic basis of isolated gonadotropin
... harbored a single, rare protein-altering variant, which was missense with one exception (nonsense; Fig. 1B and Table S3). Theoretically, such variants could be neutral, could contribute to isolated GnRH deficiency only in combination with other variants (oligogenicity), or could even be protective. I ...
... harbored a single, rare protein-altering variant, which was missense with one exception (nonsense; Fig. 1B and Table S3). Theoretically, such variants could be neutral, could contribute to isolated GnRH deficiency only in combination with other variants (oligogenicity), or could even be protective. I ...
Genetic Control of Meat Quality Traits
... These are major welfare problems as well as threatening productivity. In addition, the inadvertent selection for genetic defects linked to desirable production characteristics is a potential risk, especially when selection programes focus on a limited number of breeding individuals. The traits that ...
... These are major welfare problems as well as threatening productivity. In addition, the inadvertent selection for genetic defects linked to desirable production characteristics is a potential risk, especially when selection programes focus on a limited number of breeding individuals. The traits that ...
Microarray data normalization and data transformation
... • Density of fluors in the labeled hybridized molecules is high enough, interaction between the dye molecules can quench fluorescence • Poor labeling or hybridization can result in signals too faint to allow detection of certain expressed genes • Significant cross-hybridization • PCR oligonucleotide ...
... • Density of fluors in the labeled hybridized molecules is high enough, interaction between the dye molecules can quench fluorescence • Poor labeling or hybridization can result in signals too faint to allow detection of certain expressed genes • Significant cross-hybridization • PCR oligonucleotide ...
key
... (d) (2 pts) Which is generally worse, a big non-centromere-containing inversion or a small one? Why? The loop structure is not harmful in itself, but whenever a crossover occurs within it, half of the gametes are inviable. A large inversion is therefore worse than a small one because the chance that ...
... (d) (2 pts) Which is generally worse, a big non-centromere-containing inversion or a small one? Why? The loop structure is not harmful in itself, but whenever a crossover occurs within it, half of the gametes are inviable. A large inversion is therefore worse than a small one because the chance that ...
Advanced Genetics slides
... Chromosome Mapping § Since linked genes are only separated by crossing over events, then the higher the recombinant frequency of offspring…the greater the likelihood of there being a crossing over event between them. ...
... Chromosome Mapping § Since linked genes are only separated by crossing over events, then the higher the recombinant frequency of offspring…the greater the likelihood of there being a crossing over event between them. ...
The dual nature of homologous recombination in plants
... integrity of meiotic chromosomes. It is to be expected that more genes acting in mHR will be identified with time and that careful analyses of multiple mutations will decipher plant meiosis. For instance, some of the mutants isolated in a screen for X-ray sensitivity had also changed levels of meiot ...
... integrity of meiotic chromosomes. It is to be expected that more genes acting in mHR will be identified with time and that careful analyses of multiple mutations will decipher plant meiosis. For instance, some of the mutants isolated in a screen for X-ray sensitivity had also changed levels of meiot ...
S2 File.
... were harvested after 1 day of incubation, while wells with NaCl addition were harvested after 2 days, to ensure that cells in both conditions would be in their exponential growth phase. The pictures underneath the data bars show the corresponding stained biofilms, before extraction with methanol. Re ...
... were harvested after 1 day of incubation, while wells with NaCl addition were harvested after 2 days, to ensure that cells in both conditions would be in their exponential growth phase. The pictures underneath the data bars show the corresponding stained biofilms, before extraction with methanol. Re ...
Chp. 15
... inheritance has its physical basis in the behavior of chromosomes: Scientific inquiry The first solid evidence associating a specific gene with a specific chromosome came in the early 20th century from the work of Thomas Hunt Morgan These early experiments provided convincing evidence that the c ...
... inheritance has its physical basis in the behavior of chromosomes: Scientific inquiry The first solid evidence associating a specific gene with a specific chromosome came in the early 20th century from the work of Thomas Hunt Morgan These early experiments provided convincing evidence that the c ...
Document
... Where can phylogeny be used • For example, finding out about orthology versus paralogy • Predicting secondary structure of RNA • Predicting protein-protein interaction • Studying host-parasite relationships • Mapping cell-bound receptors onto their binding ligands • Multiple sequence alignment (e.g ...
... Where can phylogeny be used • For example, finding out about orthology versus paralogy • Predicting secondary structure of RNA • Predicting protein-protein interaction • Studying host-parasite relationships • Mapping cell-bound receptors onto their binding ligands • Multiple sequence alignment (e.g ...
Yet viruses cannot be included in the tree of life - Université Paris-Sud
... additional tree of the clamp loader protein from Mimivirus (MIMI_R395) and from Ectocarpus siliculosus virus-1 (ESV-1) with their cellular homologues. The viruses appear at the base of eukaryotes, which is taken as “evidence of deep Mimivirus gene ancestry” (Ref. 4). This kind of assertion can be te ...
... additional tree of the clamp loader protein from Mimivirus (MIMI_R395) and from Ectocarpus siliculosus virus-1 (ESV-1) with their cellular homologues. The viruses appear at the base of eukaryotes, which is taken as “evidence of deep Mimivirus gene ancestry” (Ref. 4). This kind of assertion can be te ...
