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14 Phylogenomic Approach to the Evolutionary Dynamics of Gene
14 Phylogenomic Approach to the Evolutionary Dynamics of Gene

... 200 olfactory receptor genes in the chicken genome. The expansions of these genes could conceivably be part of the genetic mechanism linking the immune and olfactory systems with mate choice, kin recognition, and social interactions in birds (Zelano and Edwards, 2002). Other gene expansions were pro ...
An Introduction to the Genetics and Molecular Biology of the F S
An Introduction to the Genetics and Molecular Biology of the F S

... equally important features, but is not as well characterized. The general principles of the numerous classical and modern approaches for investigating S. cerevisiae are described, and the explanation of terms and nomenclature used in current yeast studies are emphasized . This article should be part ...
Database of cattle candidate genes and genetic markers for
Database of cattle candidate genes and genetic markers for

... opened the possibility of exploiting heterologous animal models for comparative studies (Shook 2006). Targeted gene disruption in mice (gene knock-out experiments; KOs) revealed several mammary gland related phenotypes. The release of cattle genome sequence has enabled discovery of new markers and c ...
A Bayesian analysis of the chromosome architecture of
A Bayesian analysis of the chromosome architecture of

... the DISEASOME. In the meanwhile there are various applications of the DISEASOME that studied in detail the modular structure of the disease network14, improved algorithmic methods for predicting diseasegenes and modules15 or integrated additional data, e.g., in the form of PPI networks or metabolic ...
AtREM1, a Member of a New Family of B3 Domain
AtREM1, a Member of a New Family of B3 Domain

... DNA sequences from the Arabidopsis Genome Initiative have revealed the existence of at least 23 sequences characterized by the presence of duplicated REM domains (Table I; Fig. 2). Many of them also have acidic domains and/or the heptad hydrophobic repeats at their C-terminal regions. Fourteen of th ...
Identification and characterization of the ergochrome gene cluster in
Identification and characterization of the ergochrome gene cluster in

... nature [8]. Their concentration in the sclerotia is considerably higher (5  g/kg) than that of endocrocin and clavorubin (40 mg/kg) [8]. Ergochromes are known for their biological activity. Many of them show anti-inflammatory, cytostatic and anti-tumor activity or a neuroprotective effect [9–11]. Du ...
Recruitment of 5! Hoxa genes in the allantois is
Recruitment of 5! Hoxa genes in the allantois is

Alfred Henry Sturtevant - National Academy of Sciences
Alfred Henry Sturtevant - National Academy of Sciences

... age map. He and others had noticed, however, that excessive variation in the amount of crossing-over sometimes occurs. The factors responsible were isolated by Sturtevant and by Muller around 1915 and were shown to act as dominant cross-over suppressors. The first clue to the nature of these factors ...
Cell biology of carbohydrate metabolism
Cell biology of carbohydrate metabolism

... E-Box E-Box ...
the art and design of genetic screens
the art and design of genetic screens

Neutral and Non-Neutral Evolution of Duplicated Genes with Gene
Neutral and Non-Neutral Evolution of Duplicated Genes with Gene

development, the Linker histone H1 is essential for Drosophila
development, the Linker histone H1 is essential for Drosophila

... We generated mutant alleles of Drosophila melanogaster in which expression of the linker histone H1 can be down-regulated over a wide range by RNAi. When the H1 protein level is reduced to ;20% of the level in wildtype larvae, lethality occurs in the late larval – pupal stages of development. Here w ...
The landscape of microbial phenotypic traits and associated genes
The landscape of microbial phenotypic traits and associated genes

... occurring gene families are involved in genetic interactions conditional on at least one phenotype, suggesting that epistasis has a major role in shaping microbial gene content. ...
1 Sequential elimination of major-effect contributors
1 Sequential elimination of major-effect contributors

... Several quantitative trait loci (QTL) mapping strategies have successfully identified major-effect loci based on their strong association with the phenotype in segregating populations. Although mapping strategies have been designed to detect minor-effect loci, many of these strategies have had poor ...
Etiology : cytogenetics and microdeletions - HAL
Etiology : cytogenetics and microdeletions - HAL

... and research of mutations in these genes. Beyond these technical pitfalls, array CGH has been shown to be a powerful tool that significantly helped in the identification of genes involved in various pathologic conditions. The first instance was the identification of the gene responsible for CHARGE s ...
Function of lanI in regulation of landomycin A biosynthesis in
Function of lanI in regulation of landomycin A biosynthesis in

... depends on function of complicated, sensitive and Xexible network of diverse regulatory elements (Bibb 2005). The Wnal decision about onset of antibiotic production is made by transcriptional factors which genes are clustered with the respective antibiotic biosynthesis genes. Members of this big gro ...
A Mathematical Theory of Natural and Artificial Selection Part X
A Mathematical Theory of Natural and Artificial Selection Part X

... that after F3 the proportion of homozygous dominants is increased by inbreeding, that of heterozygotes diminished. However the proportion of recessives between Fa and Fll inclusive is higher when inbreeding is practiced than when mating is a t random. It may be remarked that there is no advantage in ...
Involvement of HLS1 in Sugar and Auxin
Involvement of HLS1 in Sugar and Auxin

... affecting a common part of the signaling pathways for both sugar-induced and sugar-repressed gene expression. HLS1 expression in vegetative and reproductive tissues was much lower (20-fold less) than that in etiolated seedlings in the dark (Lehman et al. 1996). hls1-1 and hls1-7 genes have base subs ...
Hemoglobin - Wikispaces
Hemoglobin - Wikispaces

... 1- As b-globin gene is not expressed until late fetal gestation, the physical manifestations of b- thalassemias appear only after birth. 2- Individuals with b - thalassemias minor, make some b-chains, and usually require no specific treatment. 3- Infants born with b - thalassemias major seem healthy ...
pdf
pdf

... binding site of RNA polymerase on the promoter, e.g. electrophoretic mobility shift assays (does the DNA fragment bind?), DNase footprints (where does the protein bind?) and methylation interference assays (methylation of which purines will prevent binding?). Alternative schemes will allow one to id ...
Multiple testing
Multiple testing

... Image generated with TMeV ...
Meiosis I
Meiosis I

... • First, each chromosome has groups of linked genes. • Second, it is the chromosomes that assort independently, not individual genes. • Alleles of different genes tend to be inherited together when those genes are located on the same chromosome. ...
Microsoft Word - Mapping-Traits-in-Dogs
Microsoft Word - Mapping-Traits-in-Dogs

... genome (Figure 2). Not all single-nucleotide changes are SNPs. To be classified as a SNP, the change must occur in more than 1% of the population. Figure 2. Example of a common SNP in dogs. This illustration shows three short segments of DNA sequence from chromosome 37 of the dog genome. There are t ...
A.3.1.5SecretsInGenes - Life Science Academy
A.3.1.5SecretsInGenes - Life Science Academy

Control of the acetamidase gene of Mycobacterium smegmatis by
Control of the acetamidase gene of Mycobacterium smegmatis by

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Ridge (biology)

Ridges (regions of increased gene expression) are domains of the genome with a high gene expression; the opposite of ridges are antiridges. The term was first used by Caron et al. in 2001. Characteristics of ridges are:Gene denseContain many C and G nucleobasesGenes have short intronshigh SINE repeat densitylow LINE repeat density↑ 1.0 1.1
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