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THE EVOLUTION OF DUPLICATED GENES
THE EVOLUTION OF DUPLICATED GENES

... that when Ω = 1 we have completely neutral evolution. This process was executed 1000 times for the purpose of maintaining a constant population. To make the model more stochastic, Ω was chosen from a modified Poisson distribution. When selecting a number from a Poisson process with average Λ, there ...
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... c. As we discussed in class, 5BU causes transitions and HA is specific for the CG to TA transition. You decide to isolate revertants of the original amber mutant #1. If you used 5BU as the mutagen, would you expect to isolate mutagen-induced revertants (assume only 1 mutation per phage chromosome)? ...
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90459 Genetic Variation answers-08

... • May mention that currently neutral mutations may become positive or negative as the conditions of the environment change over time. OR • That the frequency of the allele can change through chance especially if the population is / becomes small (genetic drift NOT bottleneck unless in small populati ...
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Epistasis



Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.
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