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Ch - Ranger College
Ch - Ranger College

... How can a dominant lethal allele survive in a species? How can a lethal allele be both harmful and beneficial? What percentage of human DNA is translated (codes for protein or RNA)? What is meant by the term “gene expression”? If all of the cells in an individual’s body have the same DNA why are the ...
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Epistasis



Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.
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