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1 X chromosome crossover formation and genome stability in
1 X chromosome crossover formation and genome stability in

... xnd-1(ok709); LG IV, ced-3(n717); LG V, mys-1(n3681), him-5(ok1896). Some strains were provided by the Caenorhabditis Genetics Center. xnd-1(ok709) was outcrossed multiple times for these studies due to long-term maintenance problems of the strain. Double and triple mutants were generated using sta ...
Sample pages 1 PDF
Sample pages 1 PDF

... physical length, only slightly bigger than chromosome 21, and harbors 742 genes (National Center for Biotechnology Information, Map Viewer, build 36). ...
Pulling forces acting on Hox gene clusters cause expression
Pulling forces acting on Hox gene clusters cause expression

... hypothesis that the chromatin deforming forces in the cluster may be responsible for the expression pattern of Hox genes. I think therefore that the mechanistic nature of collinearity phenomena requires a geometrodynamical approach. I have put forward a broad framework of physical principles combine ...
Peter Kunzmann Metaphors in the Language of Darwinism
Peter Kunzmann Metaphors in the Language of Darwinism

... funny won’t be told again and will „die out”. A theory that doesn’t work will be abandoned and replaced (die out) and so on. Like viruses, myriads of memes roam the internet, looking for new hosts they can „infect”. „They compete for the occupa­ tion of minds which, apart from being hosts to memes, ...
Imprinted Genes and Human Disease
Imprinted Genes and Human Disease

... of mutations of imprinted genes. We ask whether we should expect that imprinted genes are particularly fragile. That is, are they more likely to undergo mutation and/or are mutations of imprinted genes particularly likely to result in human disease? In general we consider how the field of evolutiona ...
15_Lecture_Presentation
15_Lecture_Presentation

... Recombination of Linked Genes: Crossing Over • Morgan discovered that genes can be linked, but the linkage was incomplete, as evident from recombinant phenotypes • Morgan proposed that some process must sometimes break the physical connection between genes on the same chromosome • That mechanism wa ...
Genetic Evidence that the Operator Locus is Distinct from the z gene
Genetic Evidence that the Operator Locus is Distinct from the z gene

... transposed in a @Odlac lysogen (Signer & Beckwith, 1966; Beckwith, Signer & Epstein, 1966) to the a&,, site near the tryptophan operon (trip) on the E. coli chromosome (Fig. 1). Between lac and trp is a locus determining sensitivity to the bacteriophages Tl and 480 and colicins V and B. Selection fo ...
Vertebrate DNA Transposon as a Natural Mutator
Vertebrate DNA Transposon as a Natural Mutator

... element by excision. However, mutations caused by insertion are also expected to occur. Because new mutations are presumed to be mostly recessive to wild-type genes, the possibility of revealing new mutations was low in the experimental system we used. However, we have a fish strain that is homozygo ...
EXECUTIVE SUMMARY of THE RISK ASSESSMENT AND RISK
EXECUTIVE SUMMARY of THE RISK ASSESSMENT AND RISK

... kanamycin. The marker gene was used in the laboratory during the development of the GMOs for identification and selection of plant tissues in which the serine PI genes were also present. Short regulatory sequences are also present in the GM cottons that control the expression of the introduced genes ...
Distinct and stage specific nuclear factors regulate the expression of
Distinct and stage specific nuclear factors regulate the expression of

... repression in developing and mature gametocytes [11]. Based on these studies, it has been proposed that the developmental stages of malaria parasite require coordinated modulation of expression of distinct sets of genes, which could be achieved by transcriptional and/or posttranscriptional control. ...
gene duplication in the evolution of sexual dimorphism
gene duplication in the evolution of sexual dimorphism

... whole-body hybridizations. The detection of sex-bias depends on the statistical approach and power of a given experimental design, which may partly explain differences among studies in the number of sex-biased genes identified. Furthermore, because evolutionarily recent gene duplicates are expected ...
what is galls
what is galls

... formation at noninfected sites has been described. The presence of bacteria is required for the multiplication of the shoots and also for gall persistence (126, 150). The inhibition of shoot outgrowth has been interpreted as an extreme form of apical dominance whereby the shoot primordia mutually ex ...
Genomic imprinting effects on brain development and function
Genomic imprinting effects on brain development and function

... the spatial expression patterns of individual imprinted genes have accumulated, it has become apparent that, although for many genes the pattern of imprinting corresponds to that seen in the chimaeras, there are several exceptions2. This discrepancy might arise from the ‘few genes, large effects’ ca ...
Gabriel Jimenez-Medina - Mainstream Eugenics: A Moral Imperative?
Gabriel Jimenez-Medina - Mainstream Eugenics: A Moral Imperative?

... because some parents have more discretionary income than others, but one would be hard-pressed to argue that it should be prohibited on moral grounds. Such practices occur all the time and are generally accepted. These previous arguments, regarding procreative liberty and the argument by analogy, f ...
Gene expression profiles in rice gametes and zygotes: identification
Gene expression profiles in rice gametes and zygotes: identification

... feature of zygote development is remodelling of cell polarity. For example, the vacuole in Arabidopsis zygotes becomes fragmented after fertilization, and the zygote elongates 2- to 3-fold before a large vacuole is re-assembled (Faure et  al., 2002). In rice zygotes, the vacuoles and nucleus, which ...
Conclude chromosomes and inheritance - April 9
Conclude chromosomes and inheritance - April 9

... • Inheritance of fragile X is complex, but the syndrome is more common when the abnormal chromosome is inherited from the mother. ...
The molecular genetics of head development in Drosophila
The molecular genetics of head development in Drosophila

... 'It would be too bad if the question of head segmentation ever should be finally settled; it has been for so long such fertile ground for theorizing that arthropodists would miss it as a field for mental exercise'. Snodgrass, 1960 (cited by Rempel, 1975) The development of the Drosophila embryo has ...
Pathways - Bioinformatics.ca
Pathways - Bioinformatics.ca

... – We choose the start/finish points based on “important” or easily understood compounds – Gives us the ability to conceptualize the mapping of genotype  phenotype ...
Linkage, Crossing Over, and Chromosome Mapping
Linkage, Crossing Over, and Chromosome Mapping

... Contains genetic information of an individual ...
Genetics of Asthma – Paul E. Moore MD
Genetics of Asthma – Paul E. Moore MD

... linked to asthma: ORMDL3, DENND1B, HHIP • Suggestion of link between lung development, affecting COPD and asthma ...
Ch15-Computational_Approaches_in_Comparative_Genomics
Ch15-Computational_Approaches_in_Comparative_Genomics

...  Often the differences may be more important than the similarities  E.g. Humans and chimpanzees share 98.8% overall sequence identity  Chimpanzees are not susceptible to a number of diseases that humans are, such as malaria and AIDS  Understanding the 1.2% difference may be the clues ...
BMC Genomics 10
BMC Genomics 10

... 18. The HSA 22q12-qter, which mapped to SSC 5 [19], was also not present on our map. In addition to the absence of these regions, segments from four human chromosomes were missing on SSC 2 (HSA 1), SSC3 (HSA 9) and SSC 17 (HSA 4 and 8) when comparing to the comparative segments identified by Meyers ...
Inheritance of Organelle DNA Sequences in a Citrus–Poncirus
Inheritance of Organelle DNA Sequences in a Citrus–Poncirus

... configurations. The Yates-corrected chisquared test ( Yates 1934) for a 1:1 segregation in this population was 1.9 (P ⬎ .1). This hypothesis cannot be confirmed directly because the paternal tree is no longer living. Given that P. trifoliata trees are naturally outcrossing and highly heterozygous ( ...
pr - vg
pr - vg

... Gametes (mostly) have the same allele combinations as the homologs in the parent Recombination can give rise to gametes with non-parental ...
Document
Document

... Step 8B: Gene Expression Using CuffDiff For both alignments, de-novo (Run 1A) and informed (Run 1B), we aim to collected the abundances of the expressed genes. To do this, we will utilize the CuffDiff program. ...
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Minimal genome

The concept of minimal genome assumes that genomes can be reduced to a bare minimum, given that they contain many non-essential genes of limited or situational importance to the organism. Therefore, if a collection of all the essential genes were put together, a minimum genome could be created artificially in a stable environment. By adding more genes, the creation of an organism of desired properties is possible. The concept of minimal genome arose from the observations that many genes do not appear to be necessary for survival. In order to create a new organism a scientist must determine the minimal set of genes required for metabolism and replication. This can be achieved by experimental and computational analysis of the biochemical pathways needed to carry out basic metabolism and reproduction. A good model for a minimal genome is Mycoplasma genitalium, the organism with the smallest known genome. Most genes that are used by this organism are usually considered essential for survival; based on this concept a minimal set of 256 genes has been proposed.
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