Leukaemia Section t(5;9)(q14.1;p24) SSBP2/JAK2 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... PAX5 (Nebral et al., 2009), BCR and STRN3 (Roberts et al., 2012). It is thought that these fusions result in constitutive JAK2 tyrosine kinase activity, and it is predicted that patients with BALL exhibiting one of these fusions may respond to JAK2 inhibitors (Lacronique et al., 1997; Roberts et al. ...
... PAX5 (Nebral et al., 2009), BCR and STRN3 (Roberts et al., 2012). It is thought that these fusions result in constitutive JAK2 tyrosine kinase activity, and it is predicted that patients with BALL exhibiting one of these fusions may respond to JAK2 inhibitors (Lacronique et al., 1997; Roberts et al. ...
final1-eu-marie-curie-final-report
... assay. Studies by Gerwick and co-workers on the near complete genome of Moorea producens (L. majuscula), assert that the cyanobacterium does not contain niFH genes in its genome but is endowed with substantial amount of genes for microbial association. In our study we hypothesized that if any genes ...
... assay. Studies by Gerwick and co-workers on the near complete genome of Moorea producens (L. majuscula), assert that the cyanobacterium does not contain niFH genes in its genome but is endowed with substantial amount of genes for microbial association. In our study we hypothesized that if any genes ...
1_Genbank
... Sequence databases are great tools because they offer a unique window on the past. They make it possible to answer today’s biological questions by enabling us to analyze sequences that may have been determined as many as 25 years ago, when the whole technology emerged. By doing this, they connect pa ...
... Sequence databases are great tools because they offer a unique window on the past. They make it possible to answer today’s biological questions by enabling us to analyze sequences that may have been determined as many as 25 years ago, when the whole technology emerged. By doing this, they connect pa ...
Voiumon Numberi7i983 NucleicAcids Research
... alogy of Tn1721 [2,20] and the near identity of the tet determinants of RP1 and Tn1721. In subsequent discussions results pertaining to the tet genes of RP1 and Tn1721 will be taken to be equally applicable to either determinant. Open reading frames Bennett and Shales [21] used insertional inactivat ...
... alogy of Tn1721 [2,20] and the near identity of the tet determinants of RP1 and Tn1721. In subsequent discussions results pertaining to the tet genes of RP1 and Tn1721 will be taken to be equally applicable to either determinant. Open reading frames Bennett and Shales [21] used insertional inactivat ...
Chromosomal mutations
... chromosomes in the nucleus of a eukaryotic cell – Each organism have a specific karyotype ...
... chromosomes in the nucleus of a eukaryotic cell – Each organism have a specific karyotype ...
Is targeted modification of cytokinin regulatory gene activity in Rapid
... affected by manipulation of cytokinin levels. We hypothesised that we could identify specific cytokinin regulatory genes as targets for breeders. As both cytokinin biosynthesis and metabolism are controlled by multigene families, our target was to see if specific gene family members expressed in spe ...
... affected by manipulation of cytokinin levels. We hypothesised that we could identify specific cytokinin regulatory genes as targets for breeders. As both cytokinin biosynthesis and metabolism are controlled by multigene families, our target was to see if specific gene family members expressed in spe ...
Defects in Protein Glycosylation Cause SHO1-Dependent
... for protein glycosylation. Double-mutant studies argue that a distinct signaling pathway that begins with the membrane protein Sho1 for the HOG pathway and culminates at Ste12 from the pheromone response pathway is required for enhanced FUS1 transcription. In addition, we found that mutations that d ...
... for protein glycosylation. Double-mutant studies argue that a distinct signaling pathway that begins with the membrane protein Sho1 for the HOG pathway and culminates at Ste12 from the pheromone response pathway is required for enhanced FUS1 transcription. In addition, we found that mutations that d ...
X r Y
... – The factors separated when the gametes were formed during meiosis, each gamete would get either the tall or short gene. – When random fusion of the gametes occurred during fertilization, the combinations were brought together in a 3:1 ratio, as indicated by the Punnett square. ...
... – The factors separated when the gametes were formed during meiosis, each gamete would get either the tall or short gene. – When random fusion of the gametes occurred during fertilization, the combinations were brought together in a 3:1 ratio, as indicated by the Punnett square. ...
L-Lysin-Production with Corynebacterium glutamicum
... Metabolite sensors as a high-throughput tool. a)The principle of the L-lysine sensor is based on the transcription factor LysG recognizing its effector L-lysine and the fusion of the LysG-target gene with eYFP asreporter. b)Cells accumulating higher intracellular L-lysine concentrations and carrying ...
... Metabolite sensors as a high-throughput tool. a)The principle of the L-lysine sensor is based on the transcription factor LysG recognizing its effector L-lysine and the fusion of the LysG-target gene with eYFP asreporter. b)Cells accumulating higher intracellular L-lysine concentrations and carrying ...
A statistical framework for genome
... phenotypes we observed in the nature. Pathway-based analyses can capture the differential activity of an entire structure associated with a binary trait and the interaction between distinct components thus more accurately measuring the impact of these genetic structures on traits. Second, it can det ...
... phenotypes we observed in the nature. Pathway-based analyses can capture the differential activity of an entire structure associated with a binary trait and the interaction between distinct components thus more accurately measuring the impact of these genetic structures on traits. Second, it can det ...
User Manual
... budding yeast. However, analysis of large-scale datasets continues to be overwhelmingly challenging for biologists despite recent progresses in systems biology. For example, how can one find out which complexes are enriched with aggravating/alleviating genetic interactions? How can one use genetic i ...
... budding yeast. However, analysis of large-scale datasets continues to be overwhelmingly challenging for biologists despite recent progresses in systems biology. For example, how can one find out which complexes are enriched with aggravating/alleviating genetic interactions? How can one use genetic i ...
PDF
... the case in that the proportion of haploid spermatids increased significantly (P = 0.01219) from 17.4% to 47.2% (Figure 3B). Based on their DNA sequences, Zfy1 and Zfy2 are expected to produce transcription factors that will bind to the same target genes. We therefore also generated XEY*XSry males t ...
... the case in that the proportion of haploid spermatids increased significantly (P = 0.01219) from 17.4% to 47.2% (Figure 3B). Based on their DNA sequences, Zfy1 and Zfy2 are expected to produce transcription factors that will bind to the same target genes. We therefore also generated XEY*XSry males t ...
7.1 Chromosomes and Phenotype
... 7.1 Chromosomes and Phenotype • Many human genetic disorders are caused by autosomal genes, and can be predicted the same as flower color, or Pea shape • Autosomal genetic disorders: disorders that have no relation to the sex of an individual • Can be male or female in equal porportions Ex: Albinis ...
... 7.1 Chromosomes and Phenotype • Many human genetic disorders are caused by autosomal genes, and can be predicted the same as flower color, or Pea shape • Autosomal genetic disorders: disorders that have no relation to the sex of an individual • Can be male or female in equal porportions Ex: Albinis ...
Essential Bioinformatics and Biocomputing (LSM2104
... After the discovery of a new gene or protein related to a disease, these questions are usually asked: • What is its function and structure? – Is it similar in sequence to a known gene or protein? (sequence similarity search) – Does it contain sequence pattern similar to that of a group of known gene ...
... After the discovery of a new gene or protein related to a disease, these questions are usually asked: • What is its function and structure? – Is it similar in sequence to a known gene or protein? (sequence similarity search) – Does it contain sequence pattern similar to that of a group of known gene ...
... regulatory differences are due to divergent evolution of the target structural genes. Although several regulatory anthocyanin genes have now been isolated from Antirrhinum and Petunia spp, the data are too incomplete to exclude either of these two possibilities. Molecular analysis of the an11 locus ...
Simulating the morphology of barley spike phenotypes using
... development and simulate the phenology of various crops under different conditions of growth. Examples are models for maize [5], for wheat [3] or for sunflower, rapeseed and winter wheat [33]. The relevant variables in these approaches are environmental, with genetic factors not being explicitly con ...
... development and simulate the phenology of various crops under different conditions of growth. Examples are models for maize [5], for wheat [3] or for sunflower, rapeseed and winter wheat [33]. The relevant variables in these approaches are environmental, with genetic factors not being explicitly con ...
The importance of alternative splicing in the drug discovery process
... If, on the other hand, one is interested in the complete one splice variant is desired, the oligonucleotides/siRNAs expression level of a gene, arrays could be designed that should be selected from the region unique to this variant. will detect all the variants of a specific gene with one Antisense ...
... If, on the other hand, one is interested in the complete one splice variant is desired, the oligonucleotides/siRNAs expression level of a gene, arrays could be designed that should be selected from the region unique to this variant. will detect all the variants of a specific gene with one Antisense ...
Evolutionary Origin of Recombination during Meiosis
... (or parts of chromosomes) originating from different parent cells align and undergo genetic recombination. The recombined DNA is passed on to a progeny bacterium. The core genes for meiosis were very likely present in the common ancestor of all eukaryotes Sexual reproduction involving meiosis is wid ...
... (or parts of chromosomes) originating from different parent cells align and undergo genetic recombination. The recombined DNA is passed on to a progeny bacterium. The core genes for meiosis were very likely present in the common ancestor of all eukaryotes Sexual reproduction involving meiosis is wid ...
Survey of Conserved Alternative Splicing Events
... examined Arabidopsis genes encoding SR proteins. SR protein studies in Arabidopsis are quite advanced (Kalyna and Barta 2004; Wang and Brendel 2004); in the Arabidopsis genome, there are 19 known genes encoding SR protein family members. These members are classified into seven subfamilies (table 1). ...
... examined Arabidopsis genes encoding SR proteins. SR protein studies in Arabidopsis are quite advanced (Kalyna and Barta 2004; Wang and Brendel 2004); in the Arabidopsis genome, there are 19 known genes encoding SR protein family members. These members are classified into seven subfamilies (table 1). ...
“There is no doubt that man, as an animal, inherits characteristics
... and their location on chromosomes helped transform ...
... and their location on chromosomes helped transform ...
hindlimb - bthsresearch
... • Radical change to the body plan • No Limbs! – Lost them through evolution – First the forelimb and then the hindlimb! – Fossils have been found of snakes w/ hindlimb, but no forelimb! – Primitive snakes develop a rudimentary femur (pythons) • Don’t continue to form (no SHH to extend limb - we’ll s ...
... • Radical change to the body plan • No Limbs! – Lost them through evolution – First the forelimb and then the hindlimb! – Fossils have been found of snakes w/ hindlimb, but no forelimb! – Primitive snakes develop a rudimentary femur (pythons) • Don’t continue to form (no SHH to extend limb - we’ll s ...
Dominant and Recessive Genes
... dominant gene from on parent unites with the gamete carrying the dominant gene from the other parent, the offspring produced are homozygous dominant. If the gamete carrying the dominant gene from one parent unites with the gamete carrying the recessive gene form the other parent, the offspring are h ...
... dominant gene from on parent unites with the gamete carrying the dominant gene from the other parent, the offspring produced are homozygous dominant. If the gamete carrying the dominant gene from one parent unites with the gamete carrying the recessive gene form the other parent, the offspring are h ...