SelectedJournalAsthm..
... Hakonarson H, Bjornsdottir US, Halapi E, et al. A major susceptibility gene for asthma maps to chromosome 14q24. Am J Hum Genet 2002;71:483-91. Laitinen T, Daly MJ, Rioux JD, et al. A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. ...
... Hakonarson H, Bjornsdottir US, Halapi E, et al. A major susceptibility gene for asthma maps to chromosome 14q24. Am J Hum Genet 2002;71:483-91. Laitinen T, Daly MJ, Rioux JD, et al. A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. ...
From DNA to diversity: molecular genetics and the evolution of
... history of animals and on animal developmental genetics and regulatory mechanisms. We first examine some of the major trends in animal design and evolution illustrated in the fossil record and by modern forms (Chapter 1). Next, we take an inventory of the genetic toolkit for the development of model ...
... history of animals and on animal developmental genetics and regulatory mechanisms. We first examine some of the major trends in animal design and evolution illustrated in the fossil record and by modern forms (Chapter 1). Next, we take an inventory of the genetic toolkit for the development of model ...
VegT activates Bix4 to specify endodermal
... the middle T-box site (Tm) resulted in the most striking change in expression pattern; transgenic embryos containing this reporter construct lacked expression in the endoderm even after prolonged staining. In contrast, mutation of the distal or proximal sites (Td or Tp) did not affect the strong end ...
... the middle T-box site (Tm) resulted in the most striking change in expression pattern; transgenic embryos containing this reporter construct lacked expression in the endoderm even after prolonged staining. In contrast, mutation of the distal or proximal sites (Td or Tp) did not affect the strong end ...
Boundary elements and nuclear organization
... blocking the spread of heterochromatin has been described for a variety of identified insulator elements (for a list of such elements, see West et al., 2002), suggestive of their role in preserving the separation between heterochromatin and euchromatin. Recently, the heterochromatic repressive chrom ...
... blocking the spread of heterochromatin has been described for a variety of identified insulator elements (for a list of such elements, see West et al., 2002), suggestive of their role in preserving the separation between heterochromatin and euchromatin. Recently, the heterochromatic repressive chrom ...
It`s All In the Family
... Please tell your relatives about Alpha-1 and encourage them to be tested. This will help to identify the many undiagnosed people with Alpha-1. Understanding one’s genetic risk for liver and lung disease may result in an improved life and more informed health choices. ...
... Please tell your relatives about Alpha-1 and encourage them to be tested. This will help to identify the many undiagnosed people with Alpha-1. Understanding one’s genetic risk for liver and lung disease may result in an improved life and more informed health choices. ...
Parallel Evolution of Copy-Number Variation across Continents in
... variation on both continents, lending support to the idea that they are influenced by spatially varying selection. These findings support the idea that polymorphic CNVs contribute to local adaptation in D. melanogaster. In contrast, we find very few CNVs in D. simulans that are geographically differ ...
... variation on both continents, lending support to the idea that they are influenced by spatially varying selection. These findings support the idea that polymorphic CNVs contribute to local adaptation in D. melanogaster. In contrast, we find very few CNVs in D. simulans that are geographically differ ...
chicken.db - Bioconductor
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
Genetic Homologies between Flagellar Antigens of
... present paper designate E . coli flagellar antigens in an unorthodox way by a small roman letter h plus the figure indicating specificity and the word ' coli ' to emphasize the origin of these antigens: e.g. h2coli instead of H 2. The flagellar antigens of Salmonella abony used in the experiments ar ...
... present paper designate E . coli flagellar antigens in an unorthodox way by a small roman letter h plus the figure indicating specificity and the word ' coli ' to emphasize the origin of these antigens: e.g. h2coli instead of H 2. The flagellar antigens of Salmonella abony used in the experiments ar ...
Stanford Encyclopedia of Philosophy
... several alleles at a locus where each allele contributes more height to the organism. For example, allele A could contribute .5 units to an organism's height, allele a another .5 units and so on. A contrast with additive genetic variance is dominance variance (V D ). In this case, say two alleles (A ...
... several alleles at a locus where each allele contributes more height to the organism. For example, allele A could contribute .5 units to an organism's height, allele a another .5 units and so on. A contrast with additive genetic variance is dominance variance (V D ). In this case, say two alleles (A ...
NCBI Molecular Biology Resources
... COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M17755.2 and AW874082.1. On Feb 25, 2003 this sequence version replaced gi:21361188. ...
... COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M17755.2 and AW874082.1. On Feb 25, 2003 this sequence version replaced gi:21361188. ...
Dynamic Changes in Aromatic Hydrocarbon Associated Catabolic
... extraction [14]. Total microbial DNA was quantified by UV absorption at 260 nm [15]. Primer pair BZAQ4F/R [16] were used to amplify a 484bp fragment from the, α subunit of the bcr gene. The bcr products generated were used to prepare standards for use in qPCR assays with primer BZAQ4F and PFR1 (5`TC ...
... extraction [14]. Total microbial DNA was quantified by UV absorption at 260 nm [15]. Primer pair BZAQ4F/R [16] were used to amplify a 484bp fragment from the, α subunit of the bcr gene. The bcr products generated were used to prepare standards for use in qPCR assays with primer BZAQ4F and PFR1 (5`TC ...
Congenital hereditary cataracts
... Maf, Sox, Fox and Eya There are some other genes coding for transcription factors important for eye and lens development, Maf, Sox1, Sox2, FoxC1 and FoxE3. Particularly, Maf and Sox1 act as transcription factors on the promoters of the γ-crystallin encoding genes (Cryg). The Fox-transcription factor ...
... Maf, Sox, Fox and Eya There are some other genes coding for transcription factors important for eye and lens development, Maf, Sox1, Sox2, FoxC1 and FoxE3. Particularly, Maf and Sox1 act as transcription factors on the promoters of the γ-crystallin encoding genes (Cryg). The Fox-transcription factor ...
the evolution of genomic base composition in bacteria
... codon/), which provides codon usage and GC content information based on the protein-coding genes available in GenBank (Table 1, Fig. 1). To ensure that the genomic estimates were accurate, species for which less than 30 kilobases were available were excluded from the analysis. In most comparisons, w ...
... codon/), which provides codon usage and GC content information based on the protein-coding genes available in GenBank (Table 1, Fig. 1). To ensure that the genomic estimates were accurate, species for which less than 30 kilobases were available were excluded from the analysis. In most comparisons, w ...
The University of Chicago Genetic Services Laboratories
... performed by oligonucleotide array-CGH. Partial exonic copy number changes and rearrangements of less than 400 bp may not be detected by array-CGH. Array-CGH will not detect low-level mosaicism, balanced translocations, inversions, or point mutations that may be responsible for the clinical phenotyp ...
... performed by oligonucleotide array-CGH. Partial exonic copy number changes and rearrangements of less than 400 bp may not be detected by array-CGH. Array-CGH will not detect low-level mosaicism, balanced translocations, inversions, or point mutations that may be responsible for the clinical phenotyp ...
Telomereled bouquet formation facilitates homologous chromosome
... reduction of recombination activity; therefore the observed reduction in recombination might not be a result of the problem in chromosome pairing. Chikashige et al. (1997) reported that a ®ssion yeast linear minichromosome (Ch16) was always located near the tip of the horse tail nucleus. This observ ...
... reduction of recombination activity; therefore the observed reduction in recombination might not be a result of the problem in chromosome pairing. Chikashige et al. (1997) reported that a ®ssion yeast linear minichromosome (Ch16) was always located near the tip of the horse tail nucleus. This observ ...
M2 RNA Pol Ⅰ genes
... They typically lie upstream of the gene and can have regulatory elements several kilobases away from the transcriptional start site. (Fig.11.19) ...
... They typically lie upstream of the gene and can have regulatory elements several kilobases away from the transcriptional start site. (Fig.11.19) ...
UNIVERSITAT ROVIRA I VIRGILI CODON USAGE ADAPTATION IN PROKARYOTIC GENOMES
... widely accepted that mitochondrion had a single origin, arising from a bacterial symbiont whose closest contemporary relatives are found within the a-proteobacteria (33, 34). Since its origin, the mitochondrial genome has undergone a streamlining process of genome reduction with intense periods of l ...
... widely accepted that mitochondrion had a single origin, arising from a bacterial symbiont whose closest contemporary relatives are found within the a-proteobacteria (33, 34). Since its origin, the mitochondrial genome has undergone a streamlining process of genome reduction with intense periods of l ...
Polygenes and Modifier Genes for Tetracycline and
... As a result of transformation experiments using SDS-extracted DNA, three phenotypic classes of Pen-resistant transformants were observed by Maier et al. (19756). The representative strains 4B10, 7P16 and MP81 are listed in Table 1. Identical transformants were also obtained when phenol-extracted DNA ...
... As a result of transformation experiments using SDS-extracted DNA, three phenotypic classes of Pen-resistant transformants were observed by Maier et al. (19756). The representative strains 4B10, 7P16 and MP81 are listed in Table 1. Identical transformants were also obtained when phenol-extracted DNA ...
Detection and identification of bacteria in clinical samples by 16S
... It has been reported that Gram-positive bacteria are not detected as efficiently as Gram-negative bacteria, because the Gram-positive cell wall is difficult to break down during extraction (Harris & Hartley, 2003; Schuurman et al., 2004; Rantakokko-Jalava et al., 2000; Welinder-Olsson et al., 2007). ...
... It has been reported that Gram-positive bacteria are not detected as efficiently as Gram-negative bacteria, because the Gram-positive cell wall is difficult to break down during extraction (Harris & Hartley, 2003; Schuurman et al., 2004; Rantakokko-Jalava et al., 2000; Welinder-Olsson et al., 2007). ...
"Tooth Agenesis". - Thimios Mitsiadis
... cases of tooth agenesis can help to elucidate mechanisms involved in human odontogenesis, when phenotypes are carefully evaluated and correlated with associated genotypes. Phenotypes can be restricted to the dentition or include also defects in other tissues or organs, most frequently clefts of the ...
... cases of tooth agenesis can help to elucidate mechanisms involved in human odontogenesis, when phenotypes are carefully evaluated and correlated with associated genotypes. Phenotypes can be restricted to the dentition or include also defects in other tissues or organs, most frequently clefts of the ...
12 | mendel`s experiments and heredity
... original parental traits were lost or absorbed by the blending in the offspring, but we now know that this is not the case. Mendel was the first researcher to see it. Instead of continuous characteristics, Mendel worked with traits that were inherited in distinct classes (specifically, violet versus ...
... original parental traits were lost or absorbed by the blending in the offspring, but we now know that this is not the case. Mendel was the first researcher to see it. Instead of continuous characteristics, Mendel worked with traits that were inherited in distinct classes (specifically, violet versus ...
GENETICS accepted
... incubating for 10 minutes at 70°C and slow cooling to room temperature. dsRNA was injected at a total RNA concentration of 20ng/µl into one day old adult worms which were transferred every 24 hours for 3 days to new plates. The presence of male progeny was assessed 3-5 days later. A subset of F1 pro ...
... incubating for 10 minutes at 70°C and slow cooling to room temperature. dsRNA was injected at a total RNA concentration of 20ng/µl into one day old adult worms which were transferred every 24 hours for 3 days to new plates. The presence of male progeny was assessed 3-5 days later. A subset of F1 pro ...
Population genetics by Knud Christensen
... 14. Genetic calculation applets and other programs ............................................................................................ 101 Critical Values of the Chi-Square Distribution ................................................................................................ 101 2. ...
... 14. Genetic calculation applets and other programs ............................................................................................ 101 Critical Values of the Chi-Square Distribution ................................................................................................ 101 2. ...
Fulltext - Jultika
... spectrum of the phenotypes caused by mutations in the COL2A1 gene coding for collagen II, the main cartilage collagen, is relatively well defined, but there is little data on the phenotypes caused by collagen IX and XI mutations. The structure of the human COL11A1 gene coding for the α1 chain of col ...
... spectrum of the phenotypes caused by mutations in the COL2A1 gene coding for collagen II, the main cartilage collagen, is relatively well defined, but there is little data on the phenotypes caused by collagen IX and XI mutations. The structure of the human COL11A1 gene coding for the α1 chain of col ...
Sporadic Hypertrophic Cardiomyopathy Due to De Novo Myosin
... characterized the alleles found in father (I-I), mother (1-2), son (II-1), and daughter (II-2) at eight polymorphic STRs spread throughout the genome (Methods). At each locus the children have inherited alleles present in the father's genome, rather than other alleles that exist in the general popul ...
... characterized the alleles found in father (I-I), mother (1-2), son (II-1), and daughter (II-2) at eight polymorphic STRs spread throughout the genome (Methods). At each locus the children have inherited alleles present in the father's genome, rather than other alleles that exist in the general popul ...
Genome evolution
Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.