Robust gene silencing mediated by antisense small RNAs in the
... the mechanism of silencing revealed that the newly generated AS sRNAs possess 50 -polyphosphate termini, map to introns indicating that they can be derived from nascent mRNA, are dependent on transcription of the trigger-gene fusion construct and persist after removal of the trigger plasmid, suggest ...
... the mechanism of silencing revealed that the newly generated AS sRNAs possess 50 -polyphosphate termini, map to introns indicating that they can be derived from nascent mRNA, are dependent on transcription of the trigger-gene fusion construct and persist after removal of the trigger plasmid, suggest ...
Stage- and Tissue-Specific Expression of Ethylene Receptor
... ETR1 and ERS1 are expressed ubiquitously in Arabidopsis plants, but each gene has its particular expression pattern in each tissue (Hua et al., 1998). Three genes in tomato are also differentially regulated throughout plant development (Lashbrook et al., 1998). The expression of ERS1 (Hua et al., 19 ...
... ETR1 and ERS1 are expressed ubiquitously in Arabidopsis plants, but each gene has its particular expression pattern in each tissue (Hua et al., 1998). Three genes in tomato are also differentially regulated throughout plant development (Lashbrook et al., 1998). The expression of ERS1 (Hua et al., 19 ...
MicroRNA Analysis
... NONCODE or RNAdb, Argonaute hosts additional information on the origin of an miRNA, i.e. in which host gene it is encoded, its expression in different tissues and its known or proposed function, its potential target genes including Gene Ontology annotation, as well as miRNA families and proteins kno ...
... NONCODE or RNAdb, Argonaute hosts additional information on the origin of an miRNA, i.e. in which host gene it is encoded, its expression in different tissues and its known or proposed function, its potential target genes including Gene Ontology annotation, as well as miRNA families and proteins kno ...
The Coat of Many Colors
... of two or more alternative forms of a gene at the same site on a chromosome that determine alternative characteristics in inheritance. SILV, a term in the title of Dr. Clark’s paper excerpted later in this article, is a gene that is important in pigmentation because it produces a protein that forms ...
... of two or more alternative forms of a gene at the same site on a chromosome that determine alternative characteristics in inheritance. SILV, a term in the title of Dr. Clark’s paper excerpted later in this article, is a gene that is important in pigmentation because it produces a protein that forms ...
Exam 2 Answer Key Spring 1996 Mcbio 316 - page 1
... As described above FO-1 and FO-3 complement each other, so every cell coinfected with both phage will be lysed. In contrast, the results indcate that FO-1 and FO-2 cannot complement each other, so the rare plaques observed are probably due to recombination between the two phage to produce wild-type ...
... As described above FO-1 and FO-3 complement each other, so every cell coinfected with both phage will be lysed. In contrast, the results indcate that FO-1 and FO-2 cannot complement each other, so the rare plaques observed are probably due to recombination between the two phage to produce wild-type ...
Entering the second century of maize quantitative genetics
... flavor but negatively affects germination. Conclusions about a general trait such as fitness may not be directly applicable to other, more specific traits, yet the fact that over half of the maize genome showed a detectable fitness effect implies that a large number of genes are not only involved in ...
... flavor but negatively affects germination. Conclusions about a general trait such as fitness may not be directly applicable to other, more specific traits, yet the fact that over half of the maize genome showed a detectable fitness effect implies that a large number of genes are not only involved in ...
Hox patterning of the vertebrate rib cage
... expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al., 1991). As a result of this colinear expression, more-posterior axial regions initially express greater numbers of Hox genes. The existence of a vertebrate ‘Hox code’ was proposed that would assign morphologies ...
... expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al., 1991). As a result of this colinear expression, more-posterior axial regions initially express greater numbers of Hox genes. The existence of a vertebrate ‘Hox code’ was proposed that would assign morphologies ...
Hox patterning of the vertebrate rib cage
... expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al., 1991). As a result of this colinear expression, more-posterior axial regions initially express greater numbers of Hox genes. The existence of a vertebrate ‘Hox code’ was proposed that would assign morphologies ...
... expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al., 1991). As a result of this colinear expression, more-posterior axial regions initially express greater numbers of Hox genes. The existence of a vertebrate ‘Hox code’ was proposed that would assign morphologies ...
Chapter 12 Patterns of Inheritance
... and female sexual organs are enclosed within each pea flower (see figure 12.3), and gametes produced by the male and female parts of the same flower can fuse to form viable offspring, a process termed self-fertilization. This self-fertilization takes place automatically within an individual flower ...
... and female sexual organs are enclosed within each pea flower (see figure 12.3), and gametes produced by the male and female parts of the same flower can fuse to form viable offspring, a process termed self-fertilization. This self-fertilization takes place automatically within an individual flower ...
Understanding the pathological manifestations of aromatase excess
... Aromatase excess syndrome (AEXS; Mendelian Inheritance in Man database no. 139300), formerly known as familial gynecomastia, is a rare genetic disease characterized by the preor peripubertal onset of gynecomastia. Symptoms are exclusively related to estrogen excess and are not life-threatening unlik ...
... Aromatase excess syndrome (AEXS; Mendelian Inheritance in Man database no. 139300), formerly known as familial gynecomastia, is a rare genetic disease characterized by the preor peripubertal onset of gynecomastia. Symptoms are exclusively related to estrogen excess and are not life-threatening unlik ...
The Influence of Anticodon–Codon Interactions and Modified Bases
... which all tRNA types translate the codon. This is an important part of our model of selection on codon usage. In addition to the above, there are a few cases where tRNAs with an A at the wobble position occur in four-codon families, and the A is modified to inosine (I). These tRNAs are not included ...
... which all tRNA types translate the codon. This is an important part of our model of selection on codon usage. In addition to the above, there are a few cases where tRNAs with an A at the wobble position occur in four-codon families, and the A is modified to inosine (I). These tRNAs are not included ...
Unified display of Arabidopsis thaliana physical maps from AtDB, the
... of coalescing Arabidopsis genomic sequences to build segments of contiguous sequence that will be placed on the physical map. Sequencing is being conducted at a rapid rate by the Arabidopsis Genome Initiative (AGI), which comprises six main groups: three US, one Japanese, one French and one European ...
... of coalescing Arabidopsis genomic sequences to build segments of contiguous sequence that will be placed on the physical map. Sequencing is being conducted at a rapid rate by the Arabidopsis Genome Initiative (AGI), which comprises six main groups: three US, one Japanese, one French and one European ...
SPT3 interacts with TFIID to allow normal transcription in
... To study the defects caused by sptl5-21 by a genetic approach, a selection for suppressors was carried out. The selection for sptl 5-21 suppressors relied on the phenotypes of an sptl 5-21 strain carrying the insertion mutations his4-9173 and lys2-173R2. An SPT15 + strain that contains these inserti ...
... To study the defects caused by sptl5-21 by a genetic approach, a selection for suppressors was carried out. The selection for sptl 5-21 suppressors relied on the phenotypes of an sptl 5-21 strain carrying the insertion mutations his4-9173 and lys2-173R2. An SPT15 + strain that contains these inserti ...
Structural and Functional Studies of Insertion Element IS200
... histidinol as a histidine source). The diploid remains hid”- and will not grow on minimal medium. Therefore. selection can be made for HisC+ revertants. Among these are the chromosomal deletion mutant,s that affect IS200 and are described in this paper. (i) Construction of strains containing hisG : ...
... histidinol as a histidine source). The diploid remains hid”- and will not grow on minimal medium. Therefore. selection can be made for HisC+ revertants. Among these are the chromosomal deletion mutant,s that affect IS200 and are described in this paper. (i) Construction of strains containing hisG : ...
Notch activity induces Nodal expression and mediates the
... To investigate whether these elements are functional in vivo, we utilized a transgenic approach in mice. A 355-bp fragment of the mouse Nodal promoter containing the RBPjk-binding sites was fused to a lacZ-reporter cassette to create a transgene similar to others previously shown to drive expression ...
... To investigate whether these elements are functional in vivo, we utilized a transgenic approach in mice. A 355-bp fragment of the mouse Nodal promoter containing the RBPjk-binding sites was fused to a lacZ-reporter cassette to create a transgene similar to others previously shown to drive expression ...
A genome-wide analysis of DNA methylation in buccal - VU-DARE
... restricting to the most variable CpG sites (for the top 10% CpGs of which methylation level varied most between subjects, the average heritability was 37%) 34. It was also found that gene body and intergenic regions showed higher average methylation levels, more variation between subjects, and highe ...
... restricting to the most variable CpG sites (for the top 10% CpGs of which methylation level varied most between subjects, the average heritability was 37%) 34. It was also found that gene body and intergenic regions showed higher average methylation levels, more variation between subjects, and highe ...
Recurrent Pregnancy Loss and Its Relation to Combined Parental
... Just 2 % of pregnant women experience two consecutive pregnancy losses and only 0.4 to 1% have three consecutive pregnancy losses. ...
... Just 2 % of pregnant women experience two consecutive pregnancy losses and only 0.4 to 1% have three consecutive pregnancy losses. ...
K 2
... predominant in human infections but is very rarely identified in the natural environment. In addition to that, three isolates were found to have K1, and K2 and these isolates are considered as h[18] and the presence of both antigen may be due to gene transfer mechanisms [12] Furthermore, no specific ...
... predominant in human infections but is very rarely identified in the natural environment. In addition to that, three isolates were found to have K1, and K2 and these isolates are considered as h[18] and the presence of both antigen may be due to gene transfer mechanisms [12] Furthermore, no specific ...
... on the basis of the known distribution of Mendelian genes. The word “heter osis” was chosen in the same spirit as JOHANNSEN’S word “gene,” namely that it should be free from every hypothesis. It represented a group of observable phenomena for which any subsequent student was free to propose his own ...
Primers BSHG06 - National Genetics Reference Laboratories
... This system has been used to design primers for BRCA mutation scanning in the SCOBEC High Throughput Screening facility. The BRCA primer set comprises 79 fragments ranging form 258bp to 509bp covering the entire coding regions of the two genes. To date the primers ...
... This system has been used to design primers for BRCA mutation scanning in the SCOBEC High Throughput Screening facility. The BRCA primer set comprises 79 fragments ranging form 258bp to 509bp covering the entire coding regions of the two genes. To date the primers ...
Reproductive isolation and introgression between sympatric
... differentiation inside than outside chromosomal rearrangements between recently diverged species (Michel et al. 2006; Noor et al. 2007; McGaugh et al. 2012; Barb et al. 2014; Lohse et al. 2015). Even in the absence of rearrangements, interspecific gene flow might be reduced in regions of relatively ...
... differentiation inside than outside chromosomal rearrangements between recently diverged species (Michel et al. 2006; Noor et al. 2007; McGaugh et al. 2012; Barb et al. 2014; Lohse et al. 2015). Even in the absence of rearrangements, interspecific gene flow might be reduced in regions of relatively ...
Fragile X-associated disorders (FXd)
... genes determine eye and hair color, while others determine blood type. ...
... genes determine eye and hair color, while others determine blood type. ...
Epistasis Quantitative Trait Loci and Evidence for 4 Region into
... isotype, demonstrating a qualitative effect on the autoimmune response (8, 21). A high-resolution mapping of MOG-EAE was performed in an advanced intercross line (AIL), which allows the separation of closely situated QTLs as well as detection of gene-gene interactions using a pairscan analysis (25–2 ...
... isotype, demonstrating a qualitative effect on the autoimmune response (8, 21). A high-resolution mapping of MOG-EAE was performed in an advanced intercross line (AIL), which allows the separation of closely situated QTLs as well as detection of gene-gene interactions using a pairscan analysis (25–2 ...
Pitx1 and Pitx2 are required for development of hindlimb buds
... greater penetrance of the Pitx1 null phenotype on the right than left side. In view of the predominant expression of Pitx2, a factor closely related to Pitx1, in left-side lpm, we put forward the hypothesis of a partial redundancy between these two Pitx genes. In order to ascertain the putative redu ...
... greater penetrance of the Pitx1 null phenotype on the right than left side. In view of the predominant expression of Pitx2, a factor closely related to Pitx1, in left-side lpm, we put forward the hypothesis of a partial redundancy between these two Pitx genes. In order to ascertain the putative redu ...
the kinship theory of genomic imprinting - Fischer Lab
... δai and δbj can be represented by a differentiable function of the total level of gene expression X. Then the kinship theory predicts that the evolutionarily stable strategy (ESS) at the locus will be either ‘symmetric’ or ‘asymmetric’ (21). A symmetric ESS occurs when maternally derived and paterna ...
... δai and δbj can be represented by a differentiable function of the total level of gene expression X. Then the kinship theory predicts that the evolutionarily stable strategy (ESS) at the locus will be either ‘symmetric’ or ‘asymmetric’ (21). A symmetric ESS occurs when maternally derived and paterna ...
Genome evolution
Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.