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Chromosomes
Chromosomes

... Dominant alleles: always expressed. Recessive alleles: only expressed in absence of a dominant allele. ...
Bio 30 Unit D1 Population GeneticsTAR
Bio 30 Unit D1 Population GeneticsTAR

... • Apply the Hardy-Weinberg principle to published data. ...
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Why are recessive disorders more common than dominant ones?

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scheme for the human species is illustrated in ` Vestigial structures
scheme for the human species is illustrated in ` Vestigial structures

... ' fl,ogical inf,erence. Modern evolutionary theory evolution to occur, only two processes are required. One is mutation a change in the ...
Association of the polymorphism g.8514CT in the osteopontin gene
Association of the polymorphism g.8514CT in the osteopontin gene

... daughters were used. The positive effects of an additional allele are necessarily additive, so the model used to analyse the effect of allelic substitution in PTAM data included: fixed effects of bull, the regression coefficient of number of alleles C (0, 1 or 2) at the SPP1 gene locus, and the resi ...
IS IT GENETIC? How do genes, environment and chance interact to
IS IT GENETIC? How do genes, environment and chance interact to

... multifactorial: a character that is determined by some unspecified combination of genetic and environmental factors polygenic: a character determined by the combined action of a number of different genetic loci; mathematical polygenic theory assumes there are very many loci, each with a small, addit ...
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Slide 1

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Recent Discoveres in Human Genetics
Recent Discoveres in Human Genetics

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Name

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C-13 Part II Non-Mendelian inheritance
C-13 Part II Non-Mendelian inheritance

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Down load Lecture as PowerPoint
Down load Lecture as PowerPoint

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Natural selection can only occur in the presence of
Natural selection can only occur in the presence of

... example, flight has evolved in both bats and insects; they both have structures we refer to as wings, which are adaptations to flight. However, the wings of bats and insects have evolved from very different original structures. This phenomenon is called convergent evolution, where similar traits evo ...
Class Presentation Questions 12
Class Presentation Questions 12

... 9. A half shaded circle or square on a pedigree indicates that the organism is a _______________ for a trait. It is very unlikely to ever see a pedigree with all symbols half shaded! 10. What is meant by the statement ‘the phenotype of an organism is only partially determined by its genotype? 11. En ...
Mechanisms of Evolution
Mechanisms of Evolution

... Selection- favors both extreme variations of a trait; resulting eventually in no intermediate form of the trait & leads to evolution of 2 new species For example, imagine a plant of extremely variable height that is pollinated by three different pollinators, one that was attracted to short plants, a ...
Applied Genetics
Applied Genetics

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CH-14 Sect 14

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Final Take-Home Exam

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separate PDF document
separate PDF document

... water). In biology, the building blocks are cells and genes, the latter are the primary units of inheritance. Genetics involves chromosomes, genes, alleles, and germ cells. The nucleus of each cell in the body contains chromosomes. Each chromosome is composed primarily of DNA which has thousands of ...
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Mendel`s work
Mendel`s work

... The molecular mechanism of recombination ...
Mendel`s work
Mendel`s work

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Chapter 11 ppt student notes pt 1
Chapter 11 ppt student notes pt 1

... genetic condition that is a deviation for the usual (or average) and is not life-threatening  Rare or less common version of a trait  Genetic ______________ is used to describe conditions that cause medical problems  ______________ is a recognized set of symptoms that characterize an abnormality ...
HW 2 key
HW 2 key

... 1) What does the above figure illustrate about soapberry bug evolution? How do natural selection, mutation, gene flow, and descent with modification each play a role in this system? There is natural variation in soapberry beak length. Natural selection imposed by pod size drives increased (or decrea ...
DNA FRQ practice
DNA FRQ practice

... ______Kinetochores structure: disc-shaped proteins ______Kinetochores function: spindle attachment/ alignment ______Genes or DNA structure: brief DNA description ______Genes or DNA function: codes for proteins or for RNA ______Telomeres structure: Tips, ends, noncoding repetitive sequences ______Tel ...
Evolutionary Creation: From Death to Life!
Evolutionary Creation: From Death to Life!

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Human genetic variation



Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.
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