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What is Population Genetics?
What is Population Genetics?

... Frequencies of genotypes AA, Aa, and aa relative to the frequencies of alleles A and a in populations at HardyWeinberg equilibrium ...
Chapter 4 - Modern GENETICS
Chapter 4 - Modern GENETICS

CHAPTER 11 QUICK LAB
CHAPTER 11 QUICK LAB

... 1. Shuffle the cards and hold the deck face down. Turn over 40 cards to represent the alleles of 20 offspring produced by random matings in the initial population. 2. Separate the 40 cards by suit. Find the allele frequencies for the offspring by calculating the percentage of each suit. 3. Suppose a ...
Lecture 9
Lecture 9

... For religious, geographical (spatial, e.g., due to islands, mountains, and glaciers that isolate local populations), tribal or other reasons a small group of individuals may become genetically isolated from the rest of the population (genetic isolates). By chance one allele may fail to be passed on ...
handouts
handouts

... – variations occur purely by chance – variations are the real fabric of evolution – natural selection acts on these variations ...
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Natural Selection
Natural Selection

... selection, these traits of survival accumulated in a population of a species and therefore allowed the species to adapt and flourish in its environment. ...
Evolution Notes Prt II
Evolution Notes Prt II

... – Adaptation – the better adapted individuals in any population live longer and pass their successful genes to their offspring – Descent with modification – over time, natural selection will result in species with adaptations that make them well suited for survival and reproduction in that particula ...
How many chromosomes do humans have?
How many chromosomes do humans have?

... son is colorblind. How was this possible? • First, figure out the genotypes of the parents. Mom = XBXb because she has to be carrier Dad = XBY because we know he is normal • Will any of their daughters be colorblind? Will any of their daughters be carriers? • Do the Punnett square to find out!! ...
APS Science Curriculum Unit Planner
APS Science Curriculum Unit Planner

... 7.1 The chromosomes on which genes are located can affect the expression of traits. Quick lab: Sexlinked Inheritance p. 202  7.2 Phenotype is affected by many different factors. Codominance lab p. 208.Other possibilities: Genetic word problems or a simulated blood typing lab.  7.4 Interpreting and ...
Jeopardy
Jeopardy

... segregation and independent assortment. ...
DISRUPTING GENETIC EQUILIBRIUM
DISRUPTING GENETIC EQUILIBRIUM

... II. Migration/ Gene Flow ...
2.5 Genetics - Elaine Galvin
2.5 Genetics - Elaine Galvin

... (Matching) RNA production (notion of both DNA and RNA must be given) The process of making a protein using the mRNA code a template A haploid sex cell which is capable of fusion The fusion of 2[haploid] gametes to form a [diploid] zygote An alternative form of a gene Has identical alleles [for a tra ...
Lecture notes for lecture 4. This lecture covers chapters 6 and 7 in
Lecture notes for lecture 4. This lecture covers chapters 6 and 7 in

... - For example, he found many fossils, including fossils resembling, but different from animals currently living in the same area. - He noticed that many animals have “vestigial” features, attributes that don’t currently have a function. For example, humans have a tail bone; salamanders that live in ...
Punnett Squares & Probability
Punnett Squares & Probability

...  Each offspring has two copies of a gene (alleles), one from each parent because they are segregated during gamete formation  The allele for different genes usually segregate independently of one another ...
APBio Feb7 PopGen
APBio Feb7 PopGen

... •There is variations among the alleles in our genotypes (some differences we can see in our phenotype) •Thus, there is genetic variation within our population ...
1. Molecular basis of human genetics a) Structure and function of the
1. Molecular basis of human genetics a) Structure and function of the

... conditions applying the Hardy-Weinberg rule; requirements for the assumption of Hardy-Weinberg equilibrium and important reasons for deviations from theoretical expectations iii. Gene frequency differences among different populations: selection, isolation, genetic drift, migration, founder effects, ...
what is mutation?
what is mutation?

... INSERTION: when genetic material is put into another region of DNA. This may be the insertion of 1 or more bases, or it can be part of one chromosome being inserted into another, non-homologous chromosome MISSENSE: a change in DNA sequence that changes the codon to be different amino acid. Not all m ...
TT2007 Lecture 8 HB
TT2007 Lecture 8 HB

... Genetic code- three base codons … at least one for each amino acid (degenerate code) ...
PeDRA Study Approval Form
PeDRA Study Approval Form

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Title:  P.I.’s :
Title: P.I.’s :

... phenotypes under different environmental conditions. Genetic differences determine much of this phenotypic variability. It is increasingly becoming clear that this variability cannot be completely explained by genetic mechanisms alone. Recent studies suggest that environmental factors cause epigenet ...
The way light is extracted from the butterfly`s system is more than an
The way light is extracted from the butterfly`s system is more than an

... development and has experienced positive selection in the lineage leading to Homo sapiens,” the researchers wrote. Positive selection means the gene conferred some sort of advantage, so that people who had it were more likely to have descendants than people who did not. Lahn's team estimated that 70 ...
Basic principles of DT40
Basic principles of DT40

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Study Island
Study Island

... Development of the cell theory was made possible by advances in _______. A. physics B. chemistry C. microscopy D. anatomy 2. All living organisms use energy. They also grow and reproduce. What is another characteristic of all living organisms? A. All living organisms must consume food in order to ac ...
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Human genetic variation



Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.
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