Selection in backcross programmes
... unclear how to assess the latter observation. It should be considered as more than successful from the breeder’s perspective. However, would someone concerned with a more fundamental understanding of the genetic bases of quantitative traits consider such unexpected results ‘successful’? Probably the ...
... unclear how to assess the latter observation. It should be considered as more than successful from the breeder’s perspective. However, would someone concerned with a more fundamental understanding of the genetic bases of quantitative traits consider such unexpected results ‘successful’? Probably the ...
Consulta: subjectFacets:"Phenotype" Registros recuperados: 25
... Significant advances recently occurred in Coffea canephora research, such as the completion of its full genome sequencing. The information generated can be used in advanced molecular approaches for genetic improvement, like genome-wide selection programs (GWS). The purpose of this study was the phen ...
... Significant advances recently occurred in Coffea canephora research, such as the completion of its full genome sequencing. The information generated can be used in advanced molecular approaches for genetic improvement, like genome-wide selection programs (GWS). The purpose of this study was the phen ...
- Stabilis Fitness
... Polymorphism: 577 R/X Function: Alpha-actinins are a family of actin-binding proteins that maintain the cytoskeleton. The ACTN3 gene encodes alpha-actinin 3, which is only present in type II (fast) muscle fibres and also has a low expression in brain tissue. Alpha-actinins are found at the Z-line of ...
... Polymorphism: 577 R/X Function: Alpha-actinins are a family of actin-binding proteins that maintain the cytoskeleton. The ACTN3 gene encodes alpha-actinin 3, which is only present in type II (fast) muscle fibres and also has a low expression in brain tissue. Alpha-actinins are found at the Z-line of ...
MOLECULAR PROFILING OF RICE (Oryza sativa L
... many characteristics, making a particular variety more popular in one region of the world than another. Rice can have a short, medium or long grain size. It can also be waxy (sticky) or non-waxy. Some rice varieties are considered aromatic. Rice also comes in many different colours including brown, ...
... many characteristics, making a particular variety more popular in one region of the world than another. Rice can have a short, medium or long grain size. It can also be waxy (sticky) or non-waxy. Some rice varieties are considered aromatic. Rice also comes in many different colours including brown, ...
Laboratory 4 Patterns of Inheritance (human)
... All members of the class will participate in the collection of the data for items 1113. One group will be assigned to summarize the class data and to present the data and background information to the class 11. Index and ring fingers (extra information in Appendix A) Some work has been done measurin ...
... All members of the class will participate in the collection of the data for items 1113. One group will be assigned to summarize the class data and to present the data and background information to the class 11. Index and ring fingers (extra information in Appendix A) Some work has been done measurin ...
Mutation Accumulation in Populations of Varying Size
... (see Degtyareva et al. 2002 for details). This procedure produced a strain with minimal residual levels of transposition, within which the msh-2 allele occurred in a nearly entirely N2 genetic background. Prior to this experiment, the strain was further backcrossed to N2 and inbred by self-fertiliza ...
... (see Degtyareva et al. 2002 for details). This procedure produced a strain with minimal residual levels of transposition, within which the msh-2 allele occurred in a nearly entirely N2 genetic background. Prior to this experiment, the strain was further backcrossed to N2 and inbred by self-fertiliza ...
Gene conversion and purifying selection shape nucleotide variation
... M opsin genes of both DNA strands from a sample of a male as only one X-chromosome is present. We sequenced only one strand for other samples if there was no nucleotide difference from the ones for which both strands were sequenced. When we found nucleotide differences in two or more individuals at ...
... M opsin genes of both DNA strands from a sample of a male as only one X-chromosome is present. We sequenced only one strand for other samples if there was no nucleotide difference from the ones for which both strands were sequenced. When we found nucleotide differences in two or more individuals at ...
Symbiotic Sympatric Speciation: Compliance with Interaction
... phenotypes of individuals with identical genotypes split into a few groups, according to instability in the developmental dynamics that are triggered with the competitive interaction among individuals. Then, through mutational change of genes, the phenotypic differences are fixed to genes, until the ...
... phenotypes of individuals with identical genotypes split into a few groups, according to instability in the developmental dynamics that are triggered with the competitive interaction among individuals. Then, through mutational change of genes, the phenotypic differences are fixed to genes, until the ...
me-6 - Genetics
... the paired region. The Fixed Pairing Region model predicts that among prototrophic recombinants selected as random spores, the more frequent class having flanking markers of parental combination represents conversion of the mutant site further from an end of the pairing region; the hybrid-DNA model, ...
... the paired region. The Fixed Pairing Region model predicts that among prototrophic recombinants selected as random spores, the more frequent class having flanking markers of parental combination represents conversion of the mutant site further from an end of the pairing region; the hybrid-DNA model, ...
Proceedings as -file
... Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
... Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
Chapter 4: Quantitative genetics I
... Most phenotypic traits have this continuous distribution in spite of the fact that all genetic variation is discrete, not continuous; for example, there are three distinct genotypes at a locus with two alleles. This continuous distribution of most traits occurs for two reasons -- most traits have mo ...
... Most phenotypic traits have this continuous distribution in spite of the fact that all genetic variation is discrete, not continuous; for example, there are three distinct genotypes at a locus with two alleles. This continuous distribution of most traits occurs for two reasons -- most traits have mo ...
Genetic Control of X Chromosome Inactivation in Mice: Definition of
... 1973; Russell and Cacheiro 1978; Rastan 1983) hypothesize that it serves as a binding site for trans-acting factors that in turn regulate the expression of other loci in the Xic, such as Xist or Tsix. The various Xce alleles are thus predicted to have differential binding affinities for this factor ...
... 1973; Russell and Cacheiro 1978; Rastan 1983) hypothesize that it serves as a binding site for trans-acting factors that in turn regulate the expression of other loci in the Xic, such as Xist or Tsix. The various Xce alleles are thus predicted to have differential binding affinities for this factor ...
evolution - Santa Fe Institute
... selection). Moreover, variation in the number of genes encoding the various traits could cause a similar correlation (cf. section Comparative Approach: Genetic Robustness, paragraph beginning ‘‘Lack of reference and control’’). Because environmental robustness confers stability to a phenotype in a v ...
... selection). Moreover, variation in the number of genes encoding the various traits could cause a similar correlation (cf. section Comparative Approach: Genetic Robustness, paragraph beginning ‘‘Lack of reference and control’’). Because environmental robustness confers stability to a phenotype in a v ...
Epigenetics for behavioral ecologists
... Second, phenotypic variation might also reflect environmentally induced epigenetic variation inherited between generations (Scoville et al. 2011). Third, the ability of an organism to produce epiallelic variation may depend on the genotype of the individual (Figure 1; Scoville et al. 2011). Still, t ...
... Second, phenotypic variation might also reflect environmentally induced epigenetic variation inherited between generations (Scoville et al. 2011). Third, the ability of an organism to produce epiallelic variation may depend on the genotype of the individual (Figure 1; Scoville et al. 2011). Still, t ...
Mar19
... Quote from Darwin: "Variation is a feature of natural populations and every population produces more progeny than its environment can manage. The consequences of this overproduction is that those individuals with the best genetic fitness for the environment will produce offspring that can more succ ...
... Quote from Darwin: "Variation is a feature of natural populations and every population produces more progeny than its environment can manage. The consequences of this overproduction is that those individuals with the best genetic fitness for the environment will produce offspring that can more succ ...
Storage cells in the bone marrow
... RARA and the leukaemia cell of M3-like/t(15;17)/PLZFRARA AML • PLZF is a transfer factor that binds to co-repressors • PLZF-RAR therefore binds to corepressors through two binding sites —dependent on RARA and independent of it • Pharmacological doses of ATRA don’t break the second bond and therefor ...
... RARA and the leukaemia cell of M3-like/t(15;17)/PLZFRARA AML • PLZF is a transfer factor that binds to co-repressors • PLZF-RAR therefore binds to corepressors through two binding sites —dependent on RARA and independent of it • Pharmacological doses of ATRA don’t break the second bond and therefor ...
LESSON 4 Understanding Genetic Tests to Detect BRCA1
... molecules, or to compare a single sequence to a collection of sequences in a database. Additional information about BLAST can be found in the Appendix. 20. Specifically, students will be performing a Nucleotide BLAST, comparing Lawler family BRCA1 DNA sequences to a DNA reference sequence from the N ...
... molecules, or to compare a single sequence to a collection of sequences in a database. Additional information about BLAST can be found in the Appendix. 20. Specifically, students will be performing a Nucleotide BLAST, comparing Lawler family BRCA1 DNA sequences to a DNA reference sequence from the N ...
Twin Studies in Psychiatry and Psychology
... burden of proof for demonstrating this on the shoulders of twin method critics. Bouchard has called this “a very difficult task” (9, p. 33). Therefore, since critics often are unable to pinpoint the “traitrelevant” environmental factors for a given condition, the twin method remains, in the view of ...
... burden of proof for demonstrating this on the shoulders of twin method critics. Bouchard has called this “a very difficult task” (9, p. 33). Therefore, since critics often are unable to pinpoint the “traitrelevant” environmental factors for a given condition, the twin method remains, in the view of ...
Morgan and Linkage
... It is easy to think of k in units of 1,000 base pairs, i.e. a kilobase or kb. The probability that recombination will occur within 1 kb downstream of our chosen nucleotide is 7(1000) ⇥ 10 9 = 7 ⇥ 10 6 . The probability of a recombination 10 kb downstream of the nucleotide is 7 ⇥ 10 5 ; 100 kb downst ...
... It is easy to think of k in units of 1,000 base pairs, i.e. a kilobase or kb. The probability that recombination will occur within 1 kb downstream of our chosen nucleotide is 7(1000) ⇥ 10 9 = 7 ⇥ 10 6 . The probability of a recombination 10 kb downstream of the nucleotide is 7 ⇥ 10 5 ; 100 kb downst ...
Fundamentals of Genetics
... passed from one parental generation to the next. The delivery of characteristics from parent to offspring is called ...
... passed from one parental generation to the next. The delivery of characteristics from parent to offspring is called ...
Drafts Disorders - NewbornScreening.info
... Most babies do not have symptoms right away because they are protected by their mother’s thyroid hormone for a few weeks after birth. After about three to four weeks of age babies must rely solely on their own thyroid hormone. If they don’t make enough, symptoms will show up at that time. A small nu ...
... Most babies do not have symptoms right away because they are protected by their mother’s thyroid hormone for a few weeks after birth. After about three to four weeks of age babies must rely solely on their own thyroid hormone. If they don’t make enough, symptoms will show up at that time. A small nu ...
Development and implementation of genomic predictions in beef cattle
... limited. Because countries like Brazil and Argentina have their own breeding strategies for taurine breeds, which are different from North America, combining genotypic and phenotypic information to improve outcomes on genomic selection has not been considered. Research by Igenity and Pfizer Animal H ...
... limited. Because countries like Brazil and Argentina have their own breeding strategies for taurine breeds, which are different from North America, combining genotypic and phenotypic information to improve outcomes on genomic selection has not been considered. Research by Igenity and Pfizer Animal H ...
Exploring Genetics Across the Middle School Science
... Credit for the activities contained within this project goes to science teacher Dr. Jeff Batten at Hawley Middle School (Granville County, N.C.) and to math teacher Rob Caine at Franklin Academy (Wake County, N.C.) for development, testing and scrutiny from a teacher’s point of view of each activity ...
... Credit for the activities contained within this project goes to science teacher Dr. Jeff Batten at Hawley Middle School (Granville County, N.C.) and to math teacher Rob Caine at Franklin Academy (Wake County, N.C.) for development, testing and scrutiny from a teacher’s point of view of each activity ...
Abundant Genetic Overlap between Blood Lipids and Immune
... To visualize the localization of the pleiotropic genetic variants associated with both blood lipids and immune-mediated diseases, we used a ‘Conjunction FDR Manhattan plot’, showing all SNPs with a significant conjunction FDR within an LD block in relation to their chromosomal location. As illustrat ...
... To visualize the localization of the pleiotropic genetic variants associated with both blood lipids and immune-mediated diseases, we used a ‘Conjunction FDR Manhattan plot’, showing all SNPs with a significant conjunction FDR within an LD block in relation to their chromosomal location. As illustrat ...
Human genetic variation
Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.