Disruption and aberrant expression of HMGA2 as a
... and HMGA2 comprise a subgroup of nonhistone chromatin accessory proteins, often referred to as architectural transcription factors. 1–3 They are low molecular mass nuclear proteins of about 100 amino acids, which each possess three copies of a nine amino-acid motif (AT-hook) that interacts with the ...
... and HMGA2 comprise a subgroup of nonhistone chromatin accessory proteins, often referred to as architectural transcription factors. 1–3 They are low molecular mass nuclear proteins of about 100 amino acids, which each possess three copies of a nine amino-acid motif (AT-hook) that interacts with the ...
Foundations of Biology
... Pharming is the use of recombinant domestic animals to produce proteins and other bioactive compounds One of the most common strategies in pharming involves engineering mammals to produce desired proteins in their milk This strategy was first used to produce t-PA in the milk of goats It is not coinc ...
... Pharming is the use of recombinant domestic animals to produce proteins and other bioactive compounds One of the most common strategies in pharming involves engineering mammals to produce desired proteins in their milk This strategy was first used to produce t-PA in the milk of goats It is not coinc ...
Bridging the transgenerational gap with epigenetic memory
... revealed that exposure of parents to environmental stimuli could affect the phenotype of several generations of descendants, suggesting that changes in epigenetic modifications induced by environmental stimuli might be passed on to descendants via the gametes. Importantly, the field has recently mad ...
... revealed that exposure of parents to environmental stimuli could affect the phenotype of several generations of descendants, suggesting that changes in epigenetic modifications induced by environmental stimuli might be passed on to descendants via the gametes. Importantly, the field has recently mad ...
THE GENETICS AND REPRODUCTIVE ISOLATING MECHANISMS
... generation or back-crosses such a decision could not be reached. In fact, nearly all previous breeders, as well as some recent ones, suffered great losses caused by diseases, owing to the faulty breeding methods, so that the poor F ~ broods were not sufficient for an accurate genetical analysis. One ...
... generation or back-crosses such a decision could not be reached. In fact, nearly all previous breeders, as well as some recent ones, suffered great losses caused by diseases, owing to the faulty breeding methods, so that the poor F ~ broods were not sufficient for an accurate genetical analysis. One ...
Basic Principles of Heredity
... the tree’s genotype still imposes some limits on its height: an oak tree will never grow to be 300 meters (almost 1000 feet) tall no matter how much sunlight, water, and fertilizer are provided. Thus, even the height of an oak tree is determined to some degree by genes. For many characteristics, bot ...
... the tree’s genotype still imposes some limits on its height: an oak tree will never grow to be 300 meters (almost 1000 feet) tall no matter how much sunlight, water, and fertilizer are provided. Thus, even the height of an oak tree is determined to some degree by genes. For many characteristics, bot ...
Vocabulary Definitions
... circulatory system the system of blood vessels and organs that transports blood to all the cells in the body (SRB, IG) classification the process by which scientists identify and organize objects and organisms, such as plants (SRB) classify to identify and organize according to similar properties o ...
... circulatory system the system of blood vessels and organs that transports blood to all the cells in the body (SRB, IG) classification the process by which scientists identify and organize objects and organisms, such as plants (SRB) classify to identify and organize according to similar properties o ...
Evolving genetic code - J
... lethal, or at least very strongly selected against. This is because in all organisms (with the possible exception of certain viruses) the code determines (by reading the mRNA) the amino acid sequences of so many highly evolved protein molecules that any change to these would be highly disadvantageou ...
... lethal, or at least very strongly selected against. This is because in all organisms (with the possible exception of certain viruses) the code determines (by reading the mRNA) the amino acid sequences of so many highly evolved protein molecules that any change to these would be highly disadvantageou ...
Chapter 1: What is PKU?
... after three or four years we saw that our daughter's quality of life was no different from that of our other children. She was quite early walking and talking, she is athletic, and lovely. She was just as normal as her siblings." ...
... after three or four years we saw that our daughter's quality of life was no different from that of our other children. She was quite early walking and talking, she is athletic, and lovely. She was just as normal as her siblings." ...
The Nicotiana tabacum genome encodes two cytoplasmic
... KpnI (three bands). Copy number reconstruction with DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thiored ...
... KpnI (three bands). Copy number reconstruction with DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thiored ...
What is p53
... allowing DNA repair to occur before replicating the genome; hence, p53 prevents the transmission of damaged genetic information from one cell generation to the next initiates apoptosis if the damage to the cell is severe (this protects the organism from the growth of damaged cells, and so loss of p5 ...
... allowing DNA repair to occur before replicating the genome; hence, p53 prevents the transmission of damaged genetic information from one cell generation to the next initiates apoptosis if the damage to the cell is severe (this protects the organism from the growth of damaged cells, and so loss of p5 ...
Plant and Soil
... modification of one subunit of dinitrogenase reductase by dinitrogenase reductase ADP-ribosyltransferase ( D R A T ) . The system can be reactivated when NH~- is exhausted, by dinitrogenase reductase activating glycohydrolase ( D R A G ) which removes the inactivating group. It is fascinating that s ...
... modification of one subunit of dinitrogenase reductase by dinitrogenase reductase ADP-ribosyltransferase ( D R A T ) . The system can be reactivated when NH~- is exhausted, by dinitrogenase reductase activating glycohydrolase ( D R A G ) which removes the inactivating group. It is fascinating that s ...
Carriers of Hemophilia What you need to know
... »» Hemophilia carriers more commonly have heavy menstrual periods, bruising, and nosebleeds. They may also bleed more during surgery, after an injury or after delivering a baby. Treatment can minimize symptoms and prevent bleeding complications. »» If desired, a carrier can learn if her fetus is aff ...
... »» Hemophilia carriers more commonly have heavy menstrual periods, bruising, and nosebleeds. They may also bleed more during surgery, after an injury or after delivering a baby. Treatment can minimize symptoms and prevent bleeding complications. »» If desired, a carrier can learn if her fetus is aff ...
Evolving genetic code
... lethal, or at least very strongly selected against. This is because in all organisms (with the possible exception of certain viruses) the code determines (by reading the mRNA) the amino acid sequences of so many highly evolved protein molecules that any change to these would be highly disadvantageou ...
... lethal, or at least very strongly selected against. This is because in all organisms (with the possible exception of certain viruses) the code determines (by reading the mRNA) the amino acid sequences of so many highly evolved protein molecules that any change to these would be highly disadvantageou ...
International Agency for Research on Cancer (IARC)
... A large number of experiments have been carried out in which aflatoxins were administered in combination (prior to, during and following) with diets, viruses, parasites, known carcinogens and a number of different chemicals in order to study the modulating effects, including chemoprevention, of the ...
... A large number of experiments have been carried out in which aflatoxins were administered in combination (prior to, during and following) with diets, viruses, parasites, known carcinogens and a number of different chemicals in order to study the modulating effects, including chemoprevention, of the ...
A glucagon-like endocrine pathway in Drosophila
... the intriguing possibility that they will provide insight into genetic determinants of human obesity and energy homeostasis (Kulkarni and Perrimon, 2005; Murphy and Bloom, 2006). In mammals, the energy storage function of the fat body is performed in separate tissues (such as liver and adipose). Bec ...
... the intriguing possibility that they will provide insight into genetic determinants of human obesity and energy homeostasis (Kulkarni and Perrimon, 2005; Murphy and Bloom, 2006). In mammals, the energy storage function of the fat body is performed in separate tissues (such as liver and adipose). Bec ...
A glucagon-like endocrine pathway in Drosophila modulates both
... the intriguing possibility that they will provide insight into genetic determinants of human obesity and energy homeostasis (Kulkarni and Perrimon, 2005; Murphy and Bloom, 2006). In mammals, the energy storage function of the fat body is performed in separate tissues (such as liver and adipose). Bec ...
... the intriguing possibility that they will provide insight into genetic determinants of human obesity and energy homeostasis (Kulkarni and Perrimon, 2005; Murphy and Bloom, 2006). In mammals, the energy storage function of the fat body is performed in separate tissues (such as liver and adipose). Bec ...
the frequency of the factor v leiden (f5)1691g>a allele among sri
... lifetime risk of developing a DVT is approximately 10%, but may be higher when having close family members who have had DVT (15). In people with homozygous Factor V Leiden or with combined inherited thrombophilia, the risk of venous thromboembolism is increased to 20 to 50 times higher although whet ...
... lifetime risk of developing a DVT is approximately 10%, but may be higher when having close family members who have had DVT (15). In people with homozygous Factor V Leiden or with combined inherited thrombophilia, the risk of venous thromboembolism is increased to 20 to 50 times higher although whet ...
De novo production of resveratrol from glucose or
... medium with 2.46 g L 1 p-coumaric acid and using a genetically engineered industrial Brazilian S. cerevisiae strain that overexpressed 4CL1 and STS (stilbene synthase) genes (Sydor et al., 2010). In the present study, we aimed to achieve de novo biosynthesis of resveratrol from cheap carbon sources, ...
... medium with 2.46 g L 1 p-coumaric acid and using a genetically engineered industrial Brazilian S. cerevisiae strain that overexpressed 4CL1 and STS (stilbene synthase) genes (Sydor et al., 2010). In the present study, we aimed to achieve de novo biosynthesis of resveratrol from cheap carbon sources, ...
BT314 Virology
... genetically manipulated to make them efficient producers of these substances. The biotechnology industry employs molecular genetic techniques to develop and mass-produce substances of commercial value. Growth hormone, insulin, and clotting factor are now produced commercially by genetically engineer ...
... genetically manipulated to make them efficient producers of these substances. The biotechnology industry employs molecular genetic techniques to develop and mass-produce substances of commercial value. Growth hormone, insulin, and clotting factor are now produced commercially by genetically engineer ...
Introduction to Genetics
... genetically manipulated to make them efficient producers of these substances. The biotechnology industry employs molecular genetic techniques to develop and mass-produce substances of commercial value. Growth hormone, insulin, and clotting factor are now produced commercially by genetically engineer ...
... genetically manipulated to make them efficient producers of these substances. The biotechnology industry employs molecular genetic techniques to develop and mass-produce substances of commercial value. Growth hormone, insulin, and clotting factor are now produced commercially by genetically engineer ...
The importance of genetic influences in asthma REVIEW H. Los* , G.H. Koppelman*
... important in the pathogenesis of asthma. Familial aggregation of asthma was probably first described by Sennertus in 1650 [26]. At the beginning of this century, R. Cooke performed two large studies on the inheritance of atopy, one in 1916 and the other in 1924 [27, 28]. The first study examined ast ...
... important in the pathogenesis of asthma. Familial aggregation of asthma was probably first described by Sennertus in 1650 [26]. At the beginning of this century, R. Cooke performed two large studies on the inheritance of atopy, one in 1916 and the other in 1924 [27, 28]. The first study examined ast ...
AN ABSTRACT OF THE THESIS OF
... resistance genes, little is known about the structure and function of quantitative resistance ...
... resistance genes, little is known about the structure and function of quantitative resistance ...
GSEA - Bioinformatics Unit
... use HUGO gene symbols to identify the genes in the gene sets. 2. Choose false to use your expression dataset "as is." In this case, you are using the probe identifiers that are in your expression dataset for the analysis. The gene sets that you use for the analysis must also use these probe identifi ...
... use HUGO gene symbols to identify the genes in the gene sets. 2. Choose false to use your expression dataset "as is." In this case, you are using the probe identifiers that are in your expression dataset for the analysis. The gene sets that you use for the analysis must also use these probe identifi ...
Chapter 2 Biological Beginnings CHAPTER 2: BIOLOGICAL
... contains genetic information. a. RNA b. Chromosome c. DNA d. Ribosome Answer: c Difficulty Level: Easy Blooms: Remember Page(s): 55 16. _____, the units of hereditary information, are short segments of DNA. They direct cells to reproduce themselves and to assemble proteins. a. Genes b. Chromosomes c ...
... contains genetic information. a. RNA b. Chromosome c. DNA d. Ribosome Answer: c Difficulty Level: Easy Blooms: Remember Page(s): 55 16. _____, the units of hereditary information, are short segments of DNA. They direct cells to reproduce themselves and to assemble proteins. a. Genes b. Chromosomes c ...
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... Page(s): 58 42. Emma and Anna are identical twins who were adopted by different families a few weeks after birth. Although genetically identical, they grew up with different physical and psychological characteristics. For example, though both inherited a tendency to grow large, Anna was slim and ath ...
... Page(s): 58 42. Emma and Anna are identical twins who were adopted by different families a few weeks after birth. Although genetically identical, they grew up with different physical and psychological characteristics. For example, though both inherited a tendency to grow large, Anna was slim and ath ...
Genetic engineering
Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is therefore a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or ""knocked out"", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. Glofish, the first GMO designed as a pet, was first sold in the United States December in 2003.Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.