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The American University in Cairo  School of Science and Engineering
The American University in Cairo School of Science and Engineering

... et al. (1983) there are three main characteristics that cause result in resistance to betalactam antibiotics: (1) production of beta-lactamases from chromosomal or plasmid genes; (2) changes in the active site(s) resulting in the loss of the ability to bind with the DQWLELRWLFV DQG   ³7UDSSLQJ ...
Mendel PowerPoint - the Bee
Mendel PowerPoint - the Bee

... Had he done so, he would have been just an obscure monk who died a long time ago in a faraway country. Fortunately, he saw the opportunity in this relatively menial task, and he became one of the founders of modern biology. Now, 150 years later we are still studying his work. ...
Standard PDF - Wiley Online Library
Standard PDF - Wiley Online Library

... about 8 million base pairs of DNA (8.5 fg) per nucleus. The genome of P. carinii f.sp. carinii is divided into 13^15 linear chromosomes that range from 300 to 700 kb in size. Eight different P. carinii f.sp. carinii karyotypes have been observed. The karyotypes of P. carinii f.sp. carinii differ due ...
Human pigmentation variation: Evolution, genetic basis, and
Human pigmentation variation: Evolution, genetic basis, and

... highly melanogenic melanocytes transfer melanosomes to surrounding immature precortical keratinocytes that will eventually differentiate and migrate to form the pigmented hair shaft (Slominski et al., 2005). The epidermal-melanin unit (skin) and the follicular-melanin unit (hair) differ in some impo ...
Human pigmentation variation: Evolution, genetic basis, and
Human pigmentation variation: Evolution, genetic basis, and

... highly melanogenic melanocytes transfer melanosomes to surrounding immature precortical keratinocytes that will eventually differentiate and migrate to form the pigmented hair shaft (Slominski et al., 2005). The epidermal-melanin unit (skin) and the follicular-melanin unit (hair) differ in some impo ...
Leukaemia Section MLL amplification in leukemia  Atlas of Genetics and Cytogenetics
Leukaemia Section MLL amplification in leukemia Atlas of Genetics and Cytogenetics

... 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies. Blood. 2004 Jan ...
Auxin signals — turning genes on and turning cells around
Auxin signals — turning genes on and turning cells around

... As is the case for auxin perception, the molecular understanding of auxin transport is far from comprehensive. Nevertheless, the past two years have seen the detailed characterization of several new members of the PIN family of putative auxin-efflux membrane proteins and the revelation of further de ...
Quantitative analysis of SMN1 and SMN2 genes based on DHPLC
Quantitative analysis of SMN1 and SMN2 genes based on DHPLC

... patients gaining the ability to walk. A locus for the three clinical types of SMA was mapped to chromosome 5q13 by linkage analysis [Scheffer et al., 2001; Wirth, 2000] and was refined to the location of the survival motor neuron (SMN) gene [Lefebvre et al., 1995]. Two almost identical copies of the ...
The Deletion Stocks of Common Wheat
The Deletion Stocks of Common Wheat

... Chromosomal breaks occurred in the progeny of a common wheat (Tritlcum aestlvum L. em Thell; 2n = 6x = 42, genome formula AABBDD) cultivar Chinese Spring with a monosomic addition of an alien chromosome from Aegllops cyllndrlca Host (2n = 4x = 28, CCDD) or A. trlunclalls L. (2n = 4x = 28, UUCC) or a ...
Resolving Individuals Contributing Trace Amounts of DNA to Highly
Resolving Individuals Contributing Trace Amounts of DNA to Highly

... components of the mixture [8]. Nevertheless, these methods based on STRs expectedly suffer from limited power when using severely degraded DNA [8,9]. Mitochondrial DNA (mtDNA) based on hypervariable region sequencing is useful when analyzing degraded DNA due to its high copy number and improved stab ...
Control of DNA excision efficiency in Paramecium
Control of DNA excision efficiency in Paramecium

... name, of the macronuclei (1,2). In Paramecium, IESs are excised from the micronuclear genome every 1000 bp on average. Since their first identification in 1994, some 80 Paramecium IESs have been characterized. IESs are usually short (26–882 bp), AT-rich (80%) DNA segments. They are invariably surrou ...
50-State Survey of Laws Regulating the
50-State Survey of Laws Regulating the

... State laws affecting the use of tissue and associated data in scientific research are found in a variety of sources, including medical records laws, privacy and health privacy laws, genetic testing/genetic information laws, and laws on human subject protection. State laws may require researchers to ...
Completion of a parasexual cycle in Candida
Completion of a parasexual cycle in Candida

... cycle could be completed via a sexual process, via a parasexual mechanism, or by both mechanisms. Here we describe conditions in which growth of a tetraploid strain of C.albicans on Saccharomyces cerevisiae `pre-sporulation' medium induced ef®cient, random chromosome loss in the tetraploid. The prod ...
hirota - Genetics
hirota - Genetics

... containing these mutations were pili+ and others were pili-. That such phenotypically similar mutants were obtained as deletion mutations may suggest the presence of subunits in cistron C which probably control piliation. The pili+ mutants having deletions for all of cistron A and at the same time, ...
Human RIF1 and protein phosphatase 1 stimulate DNA replication
Human RIF1 and protein phosphatase 1 stimulate DNA replication

... accompanied by a change in replication fork progression as reported in other instances of reduced origin frequency, or was there a different effect due to the concomitant effects on replication timing? This point should at least be discussed. Minor issues: 1/ It seems from the Methodology section th ...
Limb Girdle Muscular Dystrophy - Muscular Dystrophy Foundation of
Limb Girdle Muscular Dystrophy - Muscular Dystrophy Foundation of

... a. Some individuals earlier diagnosed as having LGMD did not have muscular dystrophy at all, but one of several clinically similar disorders such as spinal muscular atrophy (an inherited disorder of spinal nerve cells) or polymyositis (an inflammation of muscles which is not inherited). b. There are ...
Environmentally Induced Plasticity of Root Hair
Environmentally Induced Plasticity of Root Hair

... epidermal cells that lie over the clefs of underlying cortical cells (H position) form root hairs, in the aging primary root and in laterals, the number of root hair files is considerably reduced (Table I). In cross sections of primary roots, only three epidermal cells in the H position develop into ...
File - Full Spectrum Learning
File - Full Spectrum Learning

... and advocacy organization, and an international consortium of researchers, along with participating families, joined together to announce new autism genetic discoveries from the second phase of its collaborative study: the Autism Genome Project. The results were published today in the journal Nature ...
Standards and guidelines for the interpretation of sequence
Standards and guidelines for the interpretation of sequence

... significance, particularly for internal use), and this practice is not considered inconsistent with these recommendations. It should also be noted that the terms recommended here differ somewhat from the current recommendations for classifying copy-number variants detected by cytogenetic microarray. ...
PDF
PDF

... for the genitalia; sources of descriptions of thoracic structures are as previously cited (Ingham, ...
An Update on the Hereditary Spastic Paraplegias: New Genes and
An Update on the Hereditary Spastic Paraplegias: New Genes and

... “HSPome.” Many of the newly reported genes cause rare, complicated, autosomal recessive forms of HSP. NGS also has important clinical applications by facilitating the molecular diagnosis of HSP. Furthermore, common genetic forms of HSP have been studied using new disease models, such as neurons deri ...
molecular marker-based characterization of barley powdery mildew
molecular marker-based characterization of barley powdery mildew

... salinity (Stanca, 2003), as well as biotic stresses, such as fungal pathogens (Weibull et al., 2003). The control of pathogens is usually achieved by the application of fungicides during the growing season, but such practice has associated cost penalties as well as often unpredictable effects on wil ...
- DairyNZ
- DairyNZ

... Mastitis in dairy cows compromises animal welfare and results in significant economic loss. The likelihood of mastitis occurring is influenced by environmental and genetic factors. As discussed in the previous article on mastitis phenotypes (see pg 3), DairyNZ studies1 show clear links between masti ...
Inheritance involved in the pathogenesis of idiopathic scoliosis
Inheritance involved in the pathogenesis of idiopathic scoliosis

... idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree construction between human studies, an arbitrary consensus threshold for proband curve magnitude that may obscure true heritability, and the lack of a genetic model. I ...
Comparison of the Detection Limits of the Culture and PCR Methods
Comparison of the Detection Limits of the Culture and PCR Methods

... laborious, requiring prolonged incubation, selective enrichment, and reduction of the background flora, which should be followed by biochemical identification tests (12, 13). Most laboratories are unable to diagnose the anaerobic, microaerophilic, and fastidious bacteria responsible for human gastro ...
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History of genetic engineering

Genetic modification caused by human activity has been occurring since around 12,000 BC, when humans first began to domesticate organisms. Genetic engineering as the direct transfer of DNA from one organism to another was first accomplished by Herbert Boyer and Stanley Cohen in 1973. Advances have allowed scientists to manipulate and add genes to a variety of different organism and induce a range of different effects. Since 1976 the technology has been commercialised, with companies producing and selling genetically modified food and medicine.
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