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1 - European Society for Immunodeficiencies
1 - European Society for Immunodeficiencies

... granuloma, lymphoproliferation and malignancies. The most common malignancy in adult PAD is lymphoma occurring in ~4-8% of patients. Hematopoietic stem cell transplantation (HSCT) has been used for single PAD patients with secondary malignancy or suspected combined immunodeficiency, however, its ris ...
Oxford BioMedica Announces Publication of TroVax Phase II
Oxford BioMedica Announces Publication of TroVax Phase II

... TroVax (MVA-5T4) is a therapeutic cancer vaccine designed to stimulate the immune system to destroy cancerous cells expressing the 5T4 tumour antigen, which is broadly distributed throughout a wide range of solid tumours. The paper, entitled “Vaccination of castration-resistant prostate cancer patie ...
AH 120 Human Diseases
AH 120 Human Diseases

... exercise, etc Palliative treatment: Treating symptoms only without affecting the outcome  Surgery for pain relief with a terminal disease ...
Методические разработки
Методические разработки

... There have been a number of clinical studies that have tested cancer vaccines. Thus far, there is only one cancer vaccine found to improve overall survival. Sipuleucel-T (Provenge®) is approved for use in some men with metastatic prostate cancer. It stimulates an immune response to prostatic acid ph ...
Guillain-Barre Syndrome
Guillain-Barre Syndrome

... • Abs are Ig molecules that recognize, bind, neutralize and opsonize Ag for phagocytosis. They activate complement(membrane attack complex) & induce target cells to activate the inflammatory response ...
Common Sports Medicine Medical Conditions
Common Sports Medicine Medical Conditions

...  High arched palate  Aortic insufficiency murmur  Mitral valve prolapse  Lens dislocation  Myopia ...
Common Sports Medicine Medical Conditions
Common Sports Medicine Medical Conditions

...  High arched palate  Aortic insufficiency murmur  Mitral valve prolapse  Lens dislocation  Myopia ...
11 Acut inflammation BA
11 Acut inflammation BA

... Macrophages respond to pathogens by using different receptors to stimulate phagocytosis and cytokine secretion ...
impressive eradication of cherry angiomas with a long
impressive eradication of cherry angiomas with a long

... Fifty patients (14 male; 36 female) with Fitzpatrick Skin Types I - III underwent 940 nm laser treatment to remove 5,419 cosmetically objectionable cherry angiomas. The overwhelming majority of lesions (98.2%) were located on the trunk & extremities with 99 (1.8%) lesions located on the face. The 94 ...
Tomato - Late blight
Tomato - Late blight

... On leaves: Late blight lesions usually appear first as irregular, small pale to dark green water-soaked spots that are surrounded by a zone of yellowish tissue. Lesions may expand rapidly and become brown to purplish black. White spores of the fungus may be observed at the periphery of lesions, prin ...
Hypersensitivities
Hypersensitivities

...  Mom makes IgG, binds to fetal Rh+ blood, newborn born with anemia because RBCs were destroyed by fetal immune system (also hyperbilirubinemia)  Graves’ disease – antibody binds to TSH receptors and activates them  Myasthenia Gravis – antibody binds to Ach receptor (AChR) on muscle and destroys r ...
Immunology of CELIAC DISEASE
Immunology of CELIAC DISEASE

... system responds by damaging the small intestine 1 out of every 250 people may have CD; only 1 out of 10 people may be actually diagnosed and are aware of their condition because the body's own immune system causes the damage, celiac disease is considered an autoimmune disorder ...
Hemophagocytic Lymphohistiocytosis (HLH)
Hemophagocytic Lymphohistiocytosis (HLH)

... The male-to-female ratio is 4:3, with a higher prevalence in blacks than in whites. Fever, weight loss, malaise, joint pain, and night sweats may be present. Cervical lymph nodes Other areas, including extranodal regions, can be affected. These disorders can manifest with only rash or bone involveme ...
Prefixes
Prefixes

... prevents mom from making RH+ antibodies  Bilirubin- (jaundice) produced when liver breaks down RBCs; Bilibubin is a brownish yellow substance found in bile; phototherapy lamp which changes bilirubin in a form to be excreted ...
Inflammation
Inflammation

... and other mediators that is intended to eliminate the initial cause of cell injury, as well as the necrotic cells and tissues resulting from the original insult, and to initiate the process of repair. ...
Viralytics Update on CALM and STORM Clinical Trials at American
Viralytics Update on CALM and STORM Clinical Trials at American

... Phase II CALM study: Changes in the tumor micro-environment induced by the immunotherapeutic agent, Coxsackievirus A21, delivered intratumorally in patients with advanced melanoma In the second poster presentation, Viralytics Chief Scientific Officer Dr Darren Shafren reported on the intravenous del ...
Immunological investigation in Czech patients with
Immunological investigation in Czech patients with

... possible shift to Th2 type of immune reactivity. The significance of the difference between the girls with APECED and controls was tested using Man-Whitney test. The result showed clear trend, but did not reach statistical significance. The borderline pvalue is surely influenced by low number of pat ...
Hertoghe sign: an hallmark of lepromatous leprosy
Hertoghe sign: an hallmark of lepromatous leprosy

... A 56-year-old Italian man presented with diffuse erythematous lesions on his face and bilateral Hertoghe sign (Figure 1). He reported numbness of his hands and feet. He had been prisoner in Venezuela for 25 years. Physical examination revealed similar lesions on his chest, arms, feet, knees and scr ...
behcet`s disease study status report 2012final(2)
behcet`s disease study status report 2012final(2)

... limited availability of patient samples. A high school student, KGI professor and the American Behçet’s Disease Association (ABDA) used social networking to obtain patient samples to identify unrecognized differences in serum proteins between patients and controls. ABDA obtains signed informed conse ...
Hospital-acquired and community
Hospital-acquired and community

... PVL, in combination with staphylococcal protein A, destroys respiratory tissue and bacteria-engulfing immune cells. ...
Immunity
Immunity

... Phagocytes and Granulocytes Phagocytes are large white cells that can engulf and digest foreign invaders. They include monocytes, which circulate in the blood, and macrophages, which are found in tissues throughout the body, as well as neutrophils, cells that circulate in the blood but move into tis ...
PPT Version - OMICS International
PPT Version - OMICS International

... Various cofactors have been implicated in the pathogenesis of KS, including genetic susceptibility, immunologic alterations, and endocrine factors. Human herpes virus 8 (HHV-8) also known as Kaposi sarcoma-associated herpes virus (KSHV) is believed to be a major causative factor for all clinical var ...
Pathophys - Renal - Systemic_vascular_hereditary
Pathophys - Renal - Systemic_vascular_hereditary

... Clinical ...
Targeted, systemic nanotherapies for neuroinflammation
Targeted, systemic nanotherapies for neuroinflammation

... Microglia and Astrocytes • Microglia: Microglia are immune system cells that act as ...
pathology_lesions
pathology_lesions

... allergic skin reaction, red border ...
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Pathophysiology of multiple sclerosis

Multiple sclerosis (MS) is a condition where the CNS of a person present a special kind of distributed glial scars (sclerosis) which are a remaining of a previous inflammatory demyelination. MS pathophysiology is complex and still under investigation and there is no agreement about its scope. Some authors consider it a pathological entity, while others consider it a clinical entity. From a pathological point of view, the demyelinating lesions can be classified as encephalomyelitis, and sometimes the disease is known as encephalomyelitis disseminata.There are two phases for how an unknown underlying condition may cause damage in MS: First some MRI-abnormal areas with hidden damage appear in the brain and spine (NAWM, NAGM, DAWM). Second, there are leaks in the blood–brain barrier where immune cells infiltrate causing the known demyelination and axon destruction. Some clusters of activated microglia, transection of axons and myelin degeneration is present before the BBB breaks down and the immune attack beginsPathophysiology is a convergence of pathology with physiology. Pathology is the medical discipline that describes conditions typically observed during a disease state; whereas physiology is the biological discipline that describes processes or mechanisms operating within an organism. Referring to MS, the physiology refers to the different processes that lead to the development of the lesions and the pathology refers to the condition associated with the lesions.
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