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03 PACE Inflammatory process and CV - pace

... Adverse events were common and included infection, neutropenia, and increased aminotransferase levels. ...
Lipozenčić, J., Wolf, R. (2007) Atopic dermatitis: an update
Lipozenčić, J., Wolf, R. (2007) Atopic dermatitis: an update

... flexural areas and severe pruritus (1, 2). AD affects 2-5% of the general population, with ≥1020% occurrences in infants and children and 1-3% in adults (3). There is a wide variation in the prevalence of AD in different populations of the world, and it appears to increasing (4, 5). Eczematous skin ...
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LANDREAU HID a Maquet

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Complement in skin diseases

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Natural HPV immunity and vaccination strategies

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Infections in the dialysis population: A major communicable disease

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Immunological and antimicrobial molecules in human tears: a
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Chronic ulcerative stomatitis and lichen planus:
Chronic ulcerative stomatitis and lichen planus:

... Lee et al. characterized the CUS protein autoantigen and showed it to be a variant of the p53-like KET gene [6]. The CUS protein seems to be very important for epithelial development and regeneration. Anti-CUS protein antibodies may interfere with normal CUS protein function leading to chronic ulcer ...
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Pathophysiology of multiple sclerosis

Multiple sclerosis (MS) is a condition where the CNS of a person present a special kind of distributed glial scars (sclerosis) which are a remaining of a previous inflammatory demyelination. MS pathophysiology is complex and still under investigation and there is no agreement about its scope. Some authors consider it a pathological entity, while others consider it a clinical entity. From a pathological point of view, the demyelinating lesions can be classified as encephalomyelitis, and sometimes the disease is known as encephalomyelitis disseminata.There are two phases for how an unknown underlying condition may cause damage in MS: First some MRI-abnormal areas with hidden damage appear in the brain and spine (NAWM, NAGM, DAWM). Second, there are leaks in the blood–brain barrier where immune cells infiltrate causing the known demyelination and axon destruction. Some clusters of activated microglia, transection of axons and myelin degeneration is present before the BBB breaks down and the immune attack beginsPathophysiology is a convergence of pathology with physiology. Pathology is the medical discipline that describes conditions typically observed during a disease state; whereas physiology is the biological discipline that describes processes or mechanisms operating within an organism. Referring to MS, the physiology refers to the different processes that lead to the development of the lesions and the pathology refers to the condition associated with the lesions.
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