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... determination of human IFN-γ and IL-10 in serum of patient and control groups. Serum IFN-gamma level showed the distribution of serum levels of IFN-gamma in patients with VL and control group. The levels in the pretreated VL group were (60.87± 3.6) pg/ml higher than control (5.12± 0.98) pg/ml with a ...
... determination of human IFN-γ and IL-10 in serum of patient and control groups. Serum IFN-gamma level showed the distribution of serum levels of IFN-gamma in patients with VL and control group. The levels in the pretreated VL group were (60.87± 3.6) pg/ml higher than control (5.12± 0.98) pg/ml with a ...
Novel pebbles in the mosaic of autoimmunity Open Access Carlo Perricone
... be an inducer of dendritic cells and complement activation, which is capable of increasing the levels of chemokine secretion at the injection site and of enhancing the secretion of key T-helper (Th)1 and Th17-cell polarizing cytokines such as interleukin-12 [28]. All these effects lead to developmen ...
... be an inducer of dendritic cells and complement activation, which is capable of increasing the levels of chemokine secretion at the injection site and of enhancing the secretion of key T-helper (Th)1 and Th17-cell polarizing cytokines such as interleukin-12 [28]. All these effects lead to developmen ...
The Diagnosis, Staging, and Treatment Options for Mycosis Fungoides
... bone marrow donors.29 Other implicated risk factors include genetic predisposition, radiation exposure, and preexisting malignancies, although there are little supporting data.30 Some evidence suggests immunosuppression as a risk factor for MF, including cases of documented MF arising in patients in ...
... bone marrow donors.29 Other implicated risk factors include genetic predisposition, radiation exposure, and preexisting malignancies, although there are little supporting data.30 Some evidence suggests immunosuppression as a risk factor for MF, including cases of documented MF arising in patients in ...
REVIEW: THE ROLE OF INFLAMMATION IN DEPRESSION
... the Borna virus) in MDD, lipopolysaccharides (LPS) and endotoxin have been shown to induce symptoms of MDD through peripheral immune activation (Steiner et al. 2012). TLRs activate nuclear factor–κB (NF-κB) which induces an innate inflammatory response involving the release of pro-inflammatory cytok ...
... the Borna virus) in MDD, lipopolysaccharides (LPS) and endotoxin have been shown to induce symptoms of MDD through peripheral immune activation (Steiner et al. 2012). TLRs activate nuclear factor–κB (NF-κB) which induces an innate inflammatory response involving the release of pro-inflammatory cytok ...
psoriasis associated with chronic periodontitis: a rare
... Psoriasis is a relatively common chronic dermatological disease characterized by epithelial hyperplasia presenting clinically as cutaneous erythematous papules and plaques covered by whitish scales commonly observed on the extensor-dorsal cutaneous surfaces.1 Usually it develops first in young adult ...
... Psoriasis is a relatively common chronic dermatological disease characterized by epithelial hyperplasia presenting clinically as cutaneous erythematous papules and plaques covered by whitish scales commonly observed on the extensor-dorsal cutaneous surfaces.1 Usually it develops first in young adult ...
Original Research Article
... gland interacting with the thyroid cells and the apoptotic pathways are activated by certain cytokines produced locally by the T lymphocytes. It is likely that the regulation of apoptosis during this interaction between the invading lymphocytes and the defending thyroid cells, may play an important ...
... gland interacting with the thyroid cells and the apoptotic pathways are activated by certain cytokines produced locally by the T lymphocytes. It is likely that the regulation of apoptosis during this interaction between the invading lymphocytes and the defending thyroid cells, may play an important ...
Methodological Instruction to Practical Lesson № 15
... Knowlege of clinical features of inflammation is necessary for differential diagnostic of inflammational illnesses. It is necessary to remember that appearance of all five classical features is typical only for acute inflammation of the skin and mucous membranes. If inflammation arises in the inner ...
... Knowlege of clinical features of inflammation is necessary for differential diagnostic of inflammational illnesses. It is necessary to remember that appearance of all five classical features is typical only for acute inflammation of the skin and mucous membranes. If inflammation arises in the inner ...
Is a single positive blood culture for Enterococcus species
... without a positive peripheral blood culture and no signs or symptoms of infection. To determine the source of enterococcal BSI and to distinguish between true BSI and an episode of BSI with uncertain clinical significance or central line colonization, one investigator independently assessed the docu ...
... without a positive peripheral blood culture and no signs or symptoms of infection. To determine the source of enterococcal BSI and to distinguish between true BSI and an episode of BSI with uncertain clinical significance or central line colonization, one investigator independently assessed the docu ...
anaesthesia related effects on immune function
... and increases with repeat antigen exposure. Lymphocytes are its main component; they produce antibodies which can control elements of the innate immune system. 2 Lymphocytes can be divided into T lymphocytes and B lymphocytes. T lymphocytes are predominately responsible for cellular immunity and B l ...
... and increases with repeat antigen exposure. Lymphocytes are its main component; they produce antibodies which can control elements of the innate immune system. 2 Lymphocytes can be divided into T lymphocytes and B lymphocytes. T lymphocytes are predominately responsible for cellular immunity and B l ...
INTRODUCTION - HAL
... expressing the memory T cell marker, CD45RO [34]. The CD25 antigen is mainly expressed by two sets of CD4+ T cells: a large population (~50%) that expresses CD25 following activation by an immunogenic stimulus, and a minor population (~10%) that constitutively expresses CD25 and CTLA 4, a negative ...
... expressing the memory T cell marker, CD45RO [34]. The CD25 antigen is mainly expressed by two sets of CD4+ T cells: a large population (~50%) that expresses CD25 following activation by an immunogenic stimulus, and a minor population (~10%) that constitutively expresses CD25 and CTLA 4, a negative ...
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... DHEA, in parallel to modest increases in the concentrations of cortisol, estradiol, prolactin, and thyroid hormones with no changes in insulin-like growth factor-1 [11]. We have further demonstrated that the weight loss in TB patients was related to the immune and endocrine disturbances, since the b ...
... DHEA, in parallel to modest increases in the concentrations of cortisol, estradiol, prolactin, and thyroid hormones with no changes in insulin-like growth factor-1 [11]. We have further demonstrated that the weight loss in TB patients was related to the immune and endocrine disturbances, since the b ...
Biologic response modifiers in retinal vasculitis Sandeep Saxena
... irreversible destruction of the photoreceptor cells of the retina[5]. The CD4 interacts directly with major histocompatibility complex (MHC) class Ⅱ molecules on the surface of the antigen-presenting cell. Recognition of the MHC peptide complex by CD4 + T cells leads to secretion of cytokines. T Hel ...
... irreversible destruction of the photoreceptor cells of the retina[5]. The CD4 interacts directly with major histocompatibility complex (MHC) class Ⅱ molecules on the surface of the antigen-presenting cell. Recognition of the MHC peptide complex by CD4 + T cells leads to secretion of cytokines. T Hel ...
Variations in Dinitrochlorobenzene Responsivity in Untreated Leprosy
... by in vitro equivalents of CMI such as antigen-induced lymphocyte transformation ( 1 "); and by in vitro indices of CMI responsivity such as lectin-induced lymphocyte transformation ( 5 • 1 ".'") or peripheral blood T-lymphocyte enumeration (") and classification (E9. The anergic state has been more ...
... by in vitro equivalents of CMI such as antigen-induced lymphocyte transformation ( 1 "); and by in vitro indices of CMI responsivity such as lectin-induced lymphocyte transformation ( 5 • 1 ".'") or peripheral blood T-lymphocyte enumeration (") and classification (E9. The anergic state has been more ...
Review Bacteria as the cause of ulcerative colitis
... Bacteria as the cause of ulcerative colitis Ulcerative colitis (UC) is a chronic inflammatory condition of the large bowel of unknown aetiology, characterised by the presence of bloody diarrhoea and mucus associated with a negative stool culture for bacteria, ova, or parasites. This definition finds ...
... Bacteria as the cause of ulcerative colitis Ulcerative colitis (UC) is a chronic inflammatory condition of the large bowel of unknown aetiology, characterised by the presence of bloody diarrhoea and mucus associated with a negative stool culture for bacteria, ova, or parasites. This definition finds ...
ulcerative colitis
... Bacteria as the cause of ulcerative colitis Ulcerative colitis (UC) is a chronic inflammatory condition of the large bowel of unknown aetiology, characterised by the presence of bloody diarrhoea and mucus associated with a negative stool culture for bacteria, ova, or parasites. This definition finds ...
... Bacteria as the cause of ulcerative colitis Ulcerative colitis (UC) is a chronic inflammatory condition of the large bowel of unknown aetiology, characterised by the presence of bloody diarrhoea and mucus associated with a negative stool culture for bacteria, ova, or parasites. This definition finds ...
Nontuberculous mycobacteria in cystic fibrosis associated with allergic bronchopulmonary aspergillosis and
... expiratory volume in one second dropped 18–46%. Despite prolonged triple antibiotic therapy, M. abscessus was not eradicated, and four out of six did not return to baseline clinically. In conclusion, severe nontuberculous mycobacterial lung disease, particularly with Mycobacterium abscessus, is beco ...
... expiratory volume in one second dropped 18–46%. Despite prolonged triple antibiotic therapy, M. abscessus was not eradicated, and four out of six did not return to baseline clinically. In conclusion, severe nontuberculous mycobacterial lung disease, particularly with Mycobacterium abscessus, is beco ...
Pediatr Infect Dis J 2007 Aug 26(8) 728 32
... and TNF-a mRNA are raised in lesional tissue of RAS, whereas concentrations of IL-10 mRNA are reduced in the normal mucosa of RAS patients when compared with that of control subjects. Local amounts of IFN-g are higher in the mucosa of RAS patients than in controls; whereas in contrast IL-10 values r ...
... and TNF-a mRNA are raised in lesional tissue of RAS, whereas concentrations of IL-10 mRNA are reduced in the normal mucosa of RAS patients when compared with that of control subjects. Local amounts of IFN-g are higher in the mucosa of RAS patients than in controls; whereas in contrast IL-10 values r ...
Immunologic Aspects of Hypoplastic Myelodysplastic Syndrome
... overexpressed in MDS.28 TRAIL, usually not present in healthy marrows, induces apoptosis by activating agonistic receptors 1 and 2 and decoy receptors 3 and 4.9 In MDS, TRAIL preferentially targets abnormal clonal cells with aberrant chromosomes, inducing apoptosis.28 The expression of TRAIL agonist ...
... overexpressed in MDS.28 TRAIL, usually not present in healthy marrows, induces apoptosis by activating agonistic receptors 1 and 2 and decoy receptors 3 and 4.9 In MDS, TRAIL preferentially targets abnormal clonal cells with aberrant chromosomes, inducing apoptosis.28 The expression of TRAIL agonist ...
Immunopathogenesis of chronic periapical
... among other cells, the presenceof macrophages,lymphocytes, plasma cells, PMNs, and mast cells. All of the above cells have been implicated in various types of immune response,and their presencein the periapical lesions would lend support to the contention that egress of antigens from the root canal ...
... among other cells, the presenceof macrophages,lymphocytes, plasma cells, PMNs, and mast cells. All of the above cells have been implicated in various types of immune response,and their presencein the periapical lesions would lend support to the contention that egress of antigens from the root canal ...
Ribosomes in platelets protect the messenger
... frequent expression of programmed death ligand 1 (PDL1) and immunosuppressive cytokines by NK/T lymphoma cells could inhibit T-cell cytotoxicity.8,9 Indeed, in most cases, an immune deficiency is not observed in patients with NK/T-cell lymphoma, strongly suggesting that tumor cells have developed str ...
... frequent expression of programmed death ligand 1 (PDL1) and immunosuppressive cytokines by NK/T lymphoma cells could inhibit T-cell cytotoxicity.8,9 Indeed, in most cases, an immune deficiency is not observed in patients with NK/T-cell lymphoma, strongly suggesting that tumor cells have developed str ...
Substance P and Antagonists of the Neurokinin
... tissue invasion of blood-derived leukocytes of the adaptive immune system (T and B lymphocytes) is prominent in MS and widely accepted to be disease-promoting31. In contrast, the pathogeneses of PD and AD are thought to be naturally occurring processes that involve innate components such as microgli ...
... tissue invasion of blood-derived leukocytes of the adaptive immune system (T and B lymphocytes) is prominent in MS and widely accepted to be disease-promoting31. In contrast, the pathogeneses of PD and AD are thought to be naturally occurring processes that involve innate components such as microgli ...
Anti-IgE: Beyond Asthma
... Various antigen-presenting cells are also involved in this immunologic process Langerhans cells, dendritic cells, and macrophages Langerhans cells are increased in number in chronic AD lesions, express FcRII and FcRI (high affinity) IgE receptors, and have been found to be carrying IgE antibodies De ...
... Various antigen-presenting cells are also involved in this immunologic process Langerhans cells, dendritic cells, and macrophages Langerhans cells are increased in number in chronic AD lesions, express FcRII and FcRI (high affinity) IgE receptors, and have been found to be carrying IgE antibodies De ...
A1988P838400001
... lieved that prolactin did not exist as a human pitu- made to shrink in over 80 percent of such cases, and itary hormone separate from growth hormone, medical treatment now often replaces surgery. which was thought to be responsible for all the piWhen first introduced, wedid not know how bratuitary l ...
... lieved that prolactin did not exist as a human pitu- made to shrink in over 80 percent of such cases, and itary hormone separate from growth hormone, medical treatment now often replaces surgery. which was thought to be responsible for all the piWhen first introduced, wedid not know how bratuitary l ...
Allergy in the Management of Chronic Rhinosinusitis
... size – only helps maintain size or prevent enlargement • Allergy immunotherapy has no direct impact on this disease, however, if concomitant allergy there may still be some improvement in patient symptoms and quality of life ...
... size – only helps maintain size or prevent enlargement • Allergy immunotherapy has no direct impact on this disease, however, if concomitant allergy there may still be some improvement in patient symptoms and quality of life ...