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... large and approximately equimolar quantities. The formation of these products involves two exclusively cytoplasmic NADH2-requiring reductions, catalysed by lactate dehydrogenase and triose phosphate dehydrogenase. From the rates of glucose and lactate formation it can be calculated that over 1000 μm ...
... large and approximately equimolar quantities. The formation of these products involves two exclusively cytoplasmic NADH2-requiring reductions, catalysed by lactate dehydrogenase and triose phosphate dehydrogenase. From the rates of glucose and lactate formation it can be calculated that over 1000 μm ...
Events at the Host-Microbial Interface of the Gastrointestinal Tract III
... with the host itself to coordinate various processes. The observation that the human bacterial flora is extremely important to development, as well as in shaping the innate immune system, further reinforces this suggestion (8). Eukaryotes have a mixed existence with prokaryotes, having amicable and ...
... with the host itself to coordinate various processes. The observation that the human bacterial flora is extremely important to development, as well as in shaping the innate immune system, further reinforces this suggestion (8). Eukaryotes have a mixed existence with prokaryotes, having amicable and ...
Truncated N-glycans affect protein folding in the ER of CHO
... alkaline phosphatase (SeAP) and of H-2Kd MHC class I proteins is differentially affected in the MadIA214 cell line: secretion of SeAP is thermosensitive in this mutant, while H-2Kd maturation is restricted in a temperature independent way. Here, we study in more detail the fate of glycoproteins in t ...
... alkaline phosphatase (SeAP) and of H-2Kd MHC class I proteins is differentially affected in the MadIA214 cell line: secretion of SeAP is thermosensitive in this mutant, while H-2Kd maturation is restricted in a temperature independent way. Here, we study in more detail the fate of glycoproteins in t ...
Control and Integration of Metabolism
... This is not so important for the major metabolic pathways but does play part in some of the minor pathway. e.g. pyruvate → lactate in muscle goes to lactate in blood. As the product is removed from muscle more pyruvate could change to lactate. ...
... This is not so important for the major metabolic pathways but does play part in some of the minor pathway. e.g. pyruvate → lactate in muscle goes to lactate in blood. As the product is removed from muscle more pyruvate could change to lactate. ...
Columbus County Schools Science Curriculum Guide SUBJECT
... to an understanding of the topic. CCSS.ELA-Literacy.RST.6-8.7 Integrate quantitative or technical information expressed in words in a text with a version of that information expressed visually (e.g., in a flowchart, diagram, model, graph, or table). CCSS.ELA-Literacy.RST.6-8.9 Compare and contrast t ...
... to an understanding of the topic. CCSS.ELA-Literacy.RST.6-8.7 Integrate quantitative or technical information expressed in words in a text with a version of that information expressed visually (e.g., in a flowchart, diagram, model, graph, or table). CCSS.ELA-Literacy.RST.6-8.9 Compare and contrast t ...
Proteomics and Mass Spectroscopy
... there are far fewer protein-coding genes in the human genome than proteins in the human proteome – 20,000 to 25,000 genes coding for proteins. – about 1,000,000 proteins. • The human body may contain more than 2 million proteins, each having different functions. • The discrepancy implies that protei ...
... there are far fewer protein-coding genes in the human genome than proteins in the human proteome – 20,000 to 25,000 genes coding for proteins. – about 1,000,000 proteins. • The human body may contain more than 2 million proteins, each having different functions. • The discrepancy implies that protei ...
Nitrogen catabolite repressible GAP1 promoter, a new tool for
... ammonium, etc.). The role of Gap1 under these conditions is to scavenge external amino acids in order to be used as nitrogen sources or directly as building blocks for protein synthesis. Transcription of the GAP1 gene is promoted by two GATA-family factors, Gln3 and Gat1, which are mostly active whe ...
... ammonium, etc.). The role of Gap1 under these conditions is to scavenge external amino acids in order to be used as nitrogen sources or directly as building blocks for protein synthesis. Transcription of the GAP1 gene is promoted by two GATA-family factors, Gln3 and Gat1, which are mostly active whe ...
lectSides10
... CNS axons can regrow, but… Growth is impeded by negative elements in the environment -extracelluar matrix (laminin) is sparse; inhibitory proteoglycans increase -growth factors have different distributions compared to young brain Intracellular growth elements such as GAP-43 (important for intracellu ...
... CNS axons can regrow, but… Growth is impeded by negative elements in the environment -extracelluar matrix (laminin) is sparse; inhibitory proteoglycans increase -growth factors have different distributions compared to young brain Intracellular growth elements such as GAP-43 (important for intracellu ...
Effect of osmotic shrinkage and hormones on the expression of Na+/
... a constant intracellular osmotic conditions is critical for normal cell functioning. As the gill is one of the major osmoregulatory organs in fish, the ability of the gill epithelial cells to recover from osmotic shrinkage/swelling, may relate to fish euryhalinity. In vertebrates, hormones and growt ...
... a constant intracellular osmotic conditions is critical for normal cell functioning. As the gill is one of the major osmoregulatory organs in fish, the ability of the gill epithelial cells to recover from osmotic shrinkage/swelling, may relate to fish euryhalinity. In vertebrates, hormones and growt ...
Macromolecular Transport between the Nucleus and the Cytoplasm
... The NPC is composed of a central core that mediates transit across the NE as well as peripheral components comprised of cytoplasmic filaments and a nuclear basket that mediate transport receptor–cargo docking (Fig. 1). The proteins that make up the NPC, collectively termed nucleoporins or Nups, ancho ...
... The NPC is composed of a central core that mediates transit across the NE as well as peripheral components comprised of cytoplasmic filaments and a nuclear basket that mediate transport receptor–cargo docking (Fig. 1). The proteins that make up the NPC, collectively termed nucleoporins or Nups, ancho ...
Most Human Proteins Made in Both Nucleus and Cytoplasm Turn
... cytoplasm and nucleus (Fig. 1Aii). Pre-incubation with the translational inhibitor, anisomycin [20], reduces Aha incorporation (Fig. 1Aiii; see also the legend to Fig. S1). [The anisomycin concentration and pre-incubation time applied here are routinely used to inhibit translation to the levels we s ...
... cytoplasm and nucleus (Fig. 1Aii). Pre-incubation with the translational inhibitor, anisomycin [20], reduces Aha incorporation (Fig. 1Aiii; see also the legend to Fig. S1). [The anisomycin concentration and pre-incubation time applied here are routinely used to inhibit translation to the levels we s ...
Allantoin transport protein, PucI, from Bacillus subtilis
... and membrane proteins of the nucleobase-cation-symport-1 family of secondary active transporters. These include the sodium-coupled hydantoin transport protein, Mhp1, from Microbacterium liquefaciens, and related proteins from bacteria, fungi and plants. Membrane topology predictions for PucI were co ...
... and membrane proteins of the nucleobase-cation-symport-1 family of secondary active transporters. These include the sodium-coupled hydantoin transport protein, Mhp1, from Microbacterium liquefaciens, and related proteins from bacteria, fungi and plants. Membrane topology predictions for PucI were co ...
Structure analysis of FAAP24 reveals single-stranded DNA
... to damaged DNA or stalled replication forks. However, the DNA-binding activity of this complex was not clearly defined. We investigated how FAAP24 contributes to the DNA-interacting functions of the FANCM/FAAP24 complex by acquiring the N-terminal and C-terminal solution structures of human FAAP24. ...
... to damaged DNA or stalled replication forks. However, the DNA-binding activity of this complex was not clearly defined. We investigated how FAAP24 contributes to the DNA-interacting functions of the FANCM/FAAP24 complex by acquiring the N-terminal and C-terminal solution structures of human FAAP24. ...
Biochemistry of Signal Transduction and Regulation - Beck-Shop
... – Storage and secretion of the hormone. There are signals (electrical signals, Ca2+ signals) to trigger the secretion of stored hormones. – Transport of the hormone to the target cell. The distribution of a hormone via the circulation contributes to the accessibility of that hormone at a particular ...
... – Storage and secretion of the hormone. There are signals (electrical signals, Ca2+ signals) to trigger the secretion of stored hormones. – Transport of the hormone to the target cell. The distribution of a hormone via the circulation contributes to the accessibility of that hormone at a particular ...
Diffusion Modeling of snRNP Dynamics
... measured area from the photoactivated CB. In the first approximation, a dependence of D(x) on the radial distance x can be obtained by a linear regression D ( x) = D0 + ΔD ⋅ x , where D0 = (4.7±5.4)×10-14 m2/s and ΔD =(3.7±0.6)×10-8 m/s. Similar effect was observed when evaluating the diffusion coef ...
... measured area from the photoactivated CB. In the first approximation, a dependence of D(x) on the radial distance x can be obtained by a linear regression D ( x) = D0 + ΔD ⋅ x , where D0 = (4.7±5.4)×10-14 m2/s and ΔD =(3.7±0.6)×10-8 m/s. Similar effect was observed when evaluating the diffusion coef ...
The Origin of Primary Plastids: A Pas de Deux or a
... simplistically, rather than viewing the endosymbiotic origin of plastids as a dance of two partners, Ball et al. suggest it was a more complex, ménage à trois. The Ball et al. model has some compelling features. It provides an explanation for why primary plastids have evolved so rarely and why Arc ...
... simplistically, rather than viewing the endosymbiotic origin of plastids as a dance of two partners, Ball et al. suggest it was a more complex, ménage à trois. The Ball et al. model has some compelling features. It provides an explanation for why primary plastids have evolved so rarely and why Arc ...
pLV-RNAi - Biosettia
... RNA interference (RNAi) refers to a mechanism by which double-strand RNAs (e.g. siRNA, shRNA, and miRNA) inhibit gene expression via nucleotide sequences complementary to the targeted messenger RNA, leading to mRNA degradation or translational repression (for reviews, see [1-7]). The discovery that ...
... RNA interference (RNAi) refers to a mechanism by which double-strand RNAs (e.g. siRNA, shRNA, and miRNA) inhibit gene expression via nucleotide sequences complementary to the targeted messenger RNA, leading to mRNA degradation or translational repression (for reviews, see [1-7]). The discovery that ...
Towards High-Throughput Flim for Protein
... centre of each core was identified and stored by the operator. Each region was then imaged in an automated fashion: firstly, autofocus was performed by a software algorithm based on the Fibonacci series in widefield fluorescence mode; the region was imaged using 3 different fluorescence cubes (G-2A ...
... centre of each core was identified and stored by the operator. Each region was then imaged in an automated fashion: firstly, autofocus was performed by a software algorithm based on the Fibonacci series in widefield fluorescence mode; the region was imaged using 3 different fluorescence cubes (G-2A ...
Effects of tubulin assembly inhibitors on cell division in prokaryotes
... rod-like in shape and are typically 2^5 Wm long. Insertional inactivation of the ftsZ gene with a kanamycin cassette in this cyanobacterial strain resulted in the elongation of the cells. The maximum cell size observed increased from 4 Wm to 9 Wm and the mean cell length increased from 3.1 to 4.0 Wm ...
... rod-like in shape and are typically 2^5 Wm long. Insertional inactivation of the ftsZ gene with a kanamycin cassette in this cyanobacterial strain resulted in the elongation of the cells. The maximum cell size observed increased from 4 Wm to 9 Wm and the mean cell length increased from 3.1 to 4.0 Wm ...
C 3 Cellular Structure and Function
... able to quickly pass substances into and out of the cell. For example, it must be able to pass nutrients and oxygen into the cell and waste products out of the cell. Anything that enters or leaves a cell must cross its outer surface. It is this need to pass substances across the surface that limits ...
... able to quickly pass substances into and out of the cell. For example, it must be able to pass nutrients and oxygen into the cell and waste products out of the cell. Anything that enters or leaves a cell must cross its outer surface. It is this need to pass substances across the surface that limits ...
Are nonessential amino acids not so redundant for Chinese hamster
... behavior during fed-batch processes by clarifying the biological responses of the cells during starvation for the two nonessential amino acids that are frequently depleted [12] . Specifically, we demonstrate that depletion of either Asn or Gln leads to induction of AAR on the transcriptional level. ...
... behavior during fed-batch processes by clarifying the biological responses of the cells during starvation for the two nonessential amino acids that are frequently depleted [12] . Specifically, we demonstrate that depletion of either Asn or Gln leads to induction of AAR on the transcriptional level. ...
1: Nervous System II: Anatomy Review
... The neuron conducting the impulse toward the synapse is called the __________________ neuron. The axon terminal contains ___________ ____________ filled with ______________________. An action potential in the axon terminal of the _____________ neuron causes the chemical transmitter, also known as a ...
... The neuron conducting the impulse toward the synapse is called the __________________ neuron. The axon terminal contains ___________ ____________ filled with ______________________. An action potential in the axon terminal of the _____________ neuron causes the chemical transmitter, also known as a ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.